Chimeric Enzyme | List of Frontiers open access articles

Study Protocol

Published on 06 Nov 2025

Modifying feeding protocols in critically ill patients based on a predictive model of feeding intolerance: protocol for a multicenter cluster randomized controlled trial (the mNEED study)

in Intensive Care Medicine and Anesthesiology

Youquan Wang
Yanhua Li
Ying Chen
Yuhan Zhang
Xuewen Feng
Dongfang Lv
Yumeng Chen
Xu Bi
Yongfu Yu
Yuwei Peng

Frontiers in Medicine

doi 10.3389/fmed.2025.1649983

364 views

Original Research

Published on 06 Nov 2025

Functional analysis of a novel variant in the COL5A1 gene in a Polish patient with the classical type of Ehlers–Danlos syndrome

in Genetics of Common and Rare Diseases

Anna Junkiert-Czarnecka
Karolina Maciak
Magdalena M. Kacprzak
Agnieszka Łobodzińska
Agnieszka Sobczyńska-Tomaszewska
Aneta Jurkiewicz
Monika Gora
Beata Burzynska
Maria Pilarska-Deltow
Olga Haus

Frontiers in Genetics

doi 10.3389/fgene.2025.1689587

254 views

Systematic Review

Published on 06 Nov 2025

Effects of gut microbiota interventions on patients with schizophrenia: a systematic review and meta-analysis

in Microorganisms in Vertebrate Digestive Systems

Nianhua Ye
Xin Song
Jing Yu
Xiaolei Bao
Minghua Ye
Lisheng Jiang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1681559

346 views

Systematic Review

Published on 06 Nov 2025

A systematic review and meta-analysis of the association between arterial carbon dioxide tension and patient outcomes after cardiac arrest

in Intensive Care Medicine and Anesthesiology

Dandi Wang
Zhimao Li
Gerui Qin
Liping Cai
Ting Zhang
Hui Zhang
Yecheng Liu
Huadong Zhu

Frontiers in Medicine

doi 10.3389/fmed.2025.1687522

170 views

Original Research

Published on 06 Nov 2025

LLMCARE: early detection of cognitive impairment via transformer models enhanced by LLM-generated synthetic data

in Medicine and Public Health

Ali Zolnour
Hossein Azadmaleki
Yasaman Haghbin
Fatemeh Taherinezhad
Mohamad Javad Momeni Nezhad
Sina Rashidi
Masoud Khani
AmirSajjad Taleban
Samin Mahdizadeh Sani
Maryam Dadkhah

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1669896

317 views

Brief Research Report

Published on 06 Nov 2025

Improvements in physical activity and depression symptoms: an observational study of users of a multi-modal digital mental health platform

in Digital Mental Health

Camille E. Welcome Chamberlain
Shannon Lindsay
Brooke J. Smith
Sara Sagui Henson
Cynthia Castro Sweet
Sara M. Levens

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1394647

181 views

Original Research

Published on 06 Nov 2025

A method for analyzing interwell connectivity based on gated recurrent network with knowledge interaction

in Georeservoirs

Yingchun Ji
Liming Zhang

Frontiers in Earth Science

doi 10.3389/feart.2025.1678611

258 views

Review

Published on 06 Nov 2025

The therapeutic potential of phytochemicals in morphine tolerance: targeting microglia-mediated neuroinflammation

in Ethnopharmacology

Ruizhen Shi
Tingting Jin
Weilong Xu
Yongxin Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669257

109 views

Original Research

Published on 06 Nov 2025

Impaired and restored CD8+ T cell responses to a sequentially mutated spike epitope in Omicron variants

in Viral Immunology

Eun Joo Chung
Soyoung Park
Su-Hwan Kim
Ju-yeon Choi
Hye-Sook Jeong
Jae-Hoon Ko
Joon Young Song
Young Jae Lee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684193

475 views

Systematic Review

Published on 06 Nov 2025

Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis

in Cardiovascular Epidemiology and Prevention

Antonio Mutarelli
Alexandre N. Pantaleao
Pedro H. C. Melo
Wilson Nogueira
Alleh Nogueira
Nicole Felix
Giuliano Generoso
Rhanderson Cardoso
Adrien Lupieri
Elena Aikawa

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1615158

411 views

Systematic Review

Published on 06 Nov 2025

Efficacy of digital technology-based interventions for reducing caregiver burden and stress: a systematic review and meta-analysis

in Digital Mental Health

Maria José Lumini
Daniela França
Maria Rui Sousa
Fátima Araújo
Carla Cardoso
Marta Sá
Mafalda Lopes
Maria José Peixoto
Teresa Martins

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1636084

425 views

Review

Published on 06 Nov 2025

A scoping review of dialogic formative feedback practices in higher education

in Higher Education

Eirik Nedrehagen
Tove Sandvoll Vee
Janette Moland Stokstad
Stian Orm

Frontiers in Education

doi 10.3389/feduc.2025.1696703

131 views

Original Research

Published on 06 Nov 2025

Evaluating AI decision tools in Ecuador’s courts: efficiency, consistency, and uncertainty in legal judgments

in Technology and Law

Eliana Rodríguez-Salcedo
Carlos Martínez-Bonilla
Betty Pérez-Mayorga
Mónica Salame-Ortiz
Pamela Armas-Freire
Anita Espín-Miniguano
Eulalia Pino-Loza

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1688209

517 views

Original Research

Published on 06 Nov 2025

Safety profile of Japanese encephalitis vaccines: a comprehensive analysis of vaccine adverse event reports from 1993 to 2025

in Infectious Diseases: Epidemiology and Prevention

Fujun Liu
Qibo Ran
Huajin Zhang
Zhongyu Li
Jing Chen

Frontiers in Public Health

doi 10.3389/fpubh.2025.1647485

237 views

Original Research

Published on 06 Nov 2025

Simulated virtual reality experiences for predicting early treatment response in panic disorder

in Digital Mental Health

Byung-Hoon Kim
Jae-Jin Kim
Junhyung Kim
Jiook Cha
Sang-Won Jeon
Kang-Seob Oh
Dong-Won Shin
Sung Joon Cho

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1684001

151 views

Original Research

Published on 06 Nov 2025

Nootkatone mitigates LPS-induced acute lung injury by modulating the NF-κB and Nrf2 pathways in mice

in Veterinary Pharmacology and Toxicology

D. D. V. Hanuman
Anil Kumar Banothu
Kala Kumar Bharani
Ravi Kumar Yadala
Amit Khurana
Ambica Gadige
Nagarjuna Gandham

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1593919

154 views

Articles

Modifying feeding protocols in critically ill patients based on a predictive model of feeding intolerance: protocol for a multicenter cluster randomized controlled trial (the mNEED study)

Functional analysis of a novel variant in the COL5A1 gene in a Polish patient with the classical type of Ehlers–Danlos syndrome

Effects of gut microbiota interventions on patients with schizophrenia: a systematic review and meta-analysis

A systematic review and meta-analysis of the association between arterial carbon dioxide tension and patient outcomes after cardiac arrest

LLMCARE: early detection of cognitive impairment via transformer models enhanced by LLM-generated synthetic data

Improvements in physical activity and depression symptoms: an observational study of users of a multi-modal digital mental health platform

A method for analyzing interwell connectivity based on gated recurrent network with knowledge interaction

The therapeutic potential of phytochemicals in morphine tolerance: targeting microglia-mediated neuroinflammation

Impaired and restored CD8+ T cell responses to a sequentially mutated spike epitope in Omicron variants

Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis

Efficacy of digital technology-based interventions for reducing caregiver burden and stress: a systematic review and meta-analysis

A scoping review of dialogic formative feedback practices in higher education

Evaluating AI decision tools in Ecuador’s courts: efficiency, consistency, and uncertainty in legal judgments

Safety profile of Japanese encephalitis vaccines: a comprehensive analysis of vaccine adverse event reports from 1993 to 2025

Simulated virtual reality experiences for predicting early treatment response in panic disorder

Nootkatone mitigates LPS-induced acute lung injury by modulating the NF-κB and Nrf2 pathways in mice