Clinical High Risk | List of Frontiers open access articles

Study Protocol

Published on 02 Oct 2025

Effectiveness and safety of nurse-led early cognitive and sensory rehabilitation in patients with severe traumatic brain injury: a systematic review protocol

in Neurorehabilitation

Yandi Wen
Qiaoxia He
Lan Qin
Yuluo Du
Hongyan Yin
Xiaojuan Xiang
Yisong Xie

Frontiers in Neurology

doi 10.3389/fneur.2025.1659712

1,354 views

Original Research

Published on 02 Oct 2025

Retrospective analysis of diagnosis and treatment in 9 cases of childhood-onset methylmalonic acidemia in China

in Pediatric Neurology

Chao Fan
Li Xu
Siyi Gan
Liwen Wu
Haiyan Yang
Zeshu Ning

Frontiers in Neurology

doi 10.3389/fneur.2025.1639775

1,281 views

Case Report

Published on 02 Oct 2025

Case Report: First case of percutaneous transhepatic cholangioscopy guided triple bridge drainage between multiple bile ducts for malignant hilar biliary obstruction

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Gang Tang
Jie Zhang
Rui Chen
Jingyi Zhang
Rongxing Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1620937

504 views

Original Research

Published on 02 Oct 2025

Expression levels of interleukin-17 and interferon-γ in peripheral blood and relationship with thyroid function in patients with Hashimoto’s thyroiditis

in Micronutrient Biology

Zhiyong Huang
Jiaming Zhang
Si Chen
Mingfeng Mao
Boyong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1645736

789 views

Review

Published on 02 Oct 2025

Clinical characteristics, molecular mechanisms, and exploration of association with gastrointestinal symptoms in CHAMP1 gene variation-related neurodevelopmental disorders

in Neurogenetics

Ziming Xu
Yan Xu
Xiaoyou Tao
Chen Chen
Guojuan Dong

Frontiers in Neurology

doi 10.3389/fneur.2025.1664776

1,330 views

Review

Published on 02 Oct 2025

Role of novel protein acylation modifications in sepsis

in Inflammation

Jing Wang
Aifeng He
Lin Song
Wei Jiang
Lu Xu
Ruiqiang Zheng
Jiangquan Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657194

221 views

Original Research

Published on 02 Oct 2025

Temporal trends in malignancy incidence and outcomes among kidney transplantation recipients: a multi-center real-world evidence study using the TriNetX network (2000–2010 vs. 2010–2021)

in Alloimmunity and Transplantation

Gu-Shun Lai
Jian-Ri Li
Chuan-Shu Chen
Shian-Shiang Wang
Chia-Yen Lin
Che-Jui Yang
Hao-Chung Ho
Sheng-Chun Hung
Kun-Yuan Chiu
Cheng-Kuang Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626135

1,130 views

Case Report

Published on 02 Oct 2025

The role of radiotherapy for patients with primary tracheal carcinoma: two case reports of tracheal carina squamous cell carcinoma and literature review

in Radiation Oncology

Xiaojing Chang
Zhesen Tian
Yalei Zhao
Xiaohui Ge
Feng Li
Yu Yang
Huizhi Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1665645

600 views

Original Research

Published on 02 Oct 2025

Optimizing HLA desensitization: serum dilution strategies and platform-specific MFI thresholds for antibody-mediated rejection risk in kidney transplantation

in Alloimmunity and Transplantation

Dominique Bertrand
Céline Dard
Rangolie Kaveri
Thomas Jouve
Paolo Malvezzi
Lionel Rostaing
Dominique Guerrot
Mathilde Lemoine
Charlotte Laurent
Johan Noble

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661977

1,458 views

Core Concept

Published on 02 Oct 2025

How Skin Grafts are Used to Treat Burns

in Human Health

Omaike Sikder
Dhaarini Mahesh
Natalie Gendy
Subikshan Sathyamurthy
Tina Nia
Freddy Bishay
Tara M. Connelly

Frontiers for Young Minds

doi 10.3389/frym.2025.1513151

Original Research

Published on 02 Oct 2025

Primary adrenal lymphoma and its mimics: clinico-radiological differential diagnosis

in Adrenal Endocrinology

Przemysław Kłosowski
Natalia Brzezińska
Piotr Kmieć
Dominika Okroj
Sonia Zembrzuska
Mariusz Kujawa
Anna Babińska
Renata Świątkowska-Stodulska

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1639878

999 views

Original Research

Published on 02 Oct 2025

Analysis of current status and potential categories of nutritional literacy in elderly patients with chronic diseases: a single-center cross-sectional study

in Clinical Nutrition

Zhitong Wang
Wenxiu Jiang
Jialin Wang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1670339

266 views

Original Research

Published on 02 Oct 2025

Bulk and single-cell transcriptome profiling reveals the dynamic immune response in granulomatous amebic encephalitis caused by Balamuthia mandrillaris: a cohort study

in Comparative Immunology

Jingjia Zhang
Xinmiao Jia
Bin Yang
Ying Ge
Wei Jiang
Yang Cong
Huanwen Wu
Huifang Liu
Jingjing Tian
Yingchun Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677014

930 views

Original Research

Published on 02 Oct 2025

Noninvasive estimation of oxygenation index in pediatric critical care: an independent retrospective observational validation

in Pediatric Critical Care

Thomas E. Bachman
Christopher J. L. Newth
Nimesh Patel
Patrick A. Ross

Frontiers in Pediatrics

doi 10.3389/fped.2025.1675130

738 views

Original Research

Published on 02 Oct 2025

Germline targeted next-generation sequencing in patients with adrenal incidentalomas

in Adrenal Endocrinology

Erika Messina
Alessia Inglesi
Soraya Puglisi
Anja Barač Nekić
Valentina Morelli
Ylenia Alessi
Karin Zibar Tomsic
Serena Palmieri
Pasquale Tomaiuolo
Enrico Grosso

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1685220

597 views

Original Research

Published on 02 Oct 2025

Prediction of hemorrhagic transformation after thrombolysis based on machine learning models combined with platelet distribution width-to-count ratio

in Stroke

Xiaosheng Li
Chunyan Lei
Hongyun Xu
Churan Yuan
Yuzhen Zhou
Wen Jiang

Frontiers in Neurology

doi 10.3389/fneur.2025.1466543

180 views

Articles

Effectiveness and safety of nurse-led early cognitive and sensory rehabilitation in patients with severe traumatic brain injury: a systematic review protocol

Retrospective analysis of diagnosis and treatment in 9 cases of childhood-onset methylmalonic acidemia in China

Case Report: First case of percutaneous transhepatic cholangioscopy guided triple bridge drainage between multiple bile ducts for malignant hilar biliary obstruction

Expression levels of interleukin-17 and interferon-γ in peripheral blood and relationship with thyroid function in patients with Hashimoto’s thyroiditis

Clinical characteristics, molecular mechanisms, and exploration of association with gastrointestinal symptoms in CHAMP1 gene variation-related neurodevelopmental disorders

Role of novel protein acylation modifications in sepsis

Temporal trends in malignancy incidence and outcomes among kidney transplantation recipients: a multi-center real-world evidence study using the TriNetX network (2000–2010 vs. 2010–2021)

The role of radiotherapy for patients with primary tracheal carcinoma: two case reports of tracheal carina squamous cell carcinoma and literature review

Optimizing HLA desensitization: serum dilution strategies and platform-specific MFI thresholds for antibody-mediated rejection risk in kidney transplantation

How Skin Grafts are Used to Treat Burns

Primary adrenal lymphoma and its mimics: clinico-radiological differential diagnosis

Analysis of current status and potential categories of nutritional literacy in elderly patients with chronic diseases: a single-center cross-sectional study

Bulk and single-cell transcriptome profiling reveals the dynamic immune response in granulomatous amebic encephalitis caused by Balamuthia mandrillaris: a cohort study

Noninvasive estimation of oxygenation index in pediatric critical care: an independent retrospective observational validation

Germline targeted next-generation sequencing in patients with adrenal incidentalomas

Prediction of hemorrhagic transformation after thrombolysis based on machine learning models combined with platelet distribution width-to-count ratio