Creatine Transporter | List of Frontiers open access articles

Original Research

Published on 22 Jun 2018

A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism

in Striated Muscle Physiology

Malte Stockebrand
Ali Sasani
Devashish Das
Sönke Hornig
Irm Hermans-Borgmeyer
Hannah A. Lake
Dirk Isbrandt
Craig A. Lygate
Arend Heerschap
Axel Neu

Frontiers in Physiology

doi 10.3389/fphys.2018.00773

8,678 views
45 citations

Perspective

Published on 07 Jul 2025

An international questionnaire highlights and supports the case for including girls in Creatine Transporter Deficiency research

in Neurodevelopment

Carole Chehowah
Audrey Mittelman
Vincent des Portes

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1620586

2,724 views

Original Research

Published on 24 Mar 2023

Dodecyl creatine ester improves cognitive function and identifies key protein drivers including KIF1A and PLCB1 in a mouse model of creatine transporter deficiency

in Brain Disease Mechanisms

Aloïse Mabondzo
Rania Harati
Léa Broca-Brisson
Anne-Cécile Guyot
Narciso Costa
Francesco Cacciante
Elena Putignano
Laura Baroncelli
Matthew R. Skelton
Cathy Saab

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1118707

9,963 views
8 citations

Brief Research Report

Published on 17 Apr 2024

Epigenetic alterations in creatine transporter deficiency: a new marker for dodecyl creatine ester therapeutic efficacy monitoring

in Neuropharmacology

Léa Broca-Brisson
Clémence Disdier
Rania Harati
Rifat Hamoudi
Aloïse Mabondzo

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1362497

6,253 views
2 citations

Perspective

Published on 25 Feb 2025

How a patient-led advocacy organization supports the road to diagnosis and treatment of creatine transporter deficiency

in Neurodevelopment

Heidi Wallis
Sangeetha Iyer
Emily K. Reinhardt

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1548182

2,559 views

Review

Published on 23 Oct 2020

The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome

Clemens V. Farr
Ali El-Kasaby
Michael Freissmuth
Sonja Sucic

Frontiers in Synaptic Neuroscience

doi 10.3389/fnsyn.2020.588954

22,331 views
43 citations

Original Research

Published on 09 Aug 2022

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

in Nutrition and Metabolism

Craig A. Lygate
Hannah A. Lake
Debra J. McAndrew
Stefan Neubauer
Sevasti Zervou

Frontiers in Nutrition

doi 10.3389/fnut.2022.969702

5,413 views
4 citations

Original Research

Published on 26 Aug 2014

Creatine transporter (SLC6A8) knockout mice display an increased capacity for in vitro creatine biosynthesis in skeletal muscle

in Striated Muscle Physiology

Aaron P. Russell
Lobna Ghobrial
Craig R. Wright
Séverine Lamon
Erin L. Brown
Michihiro Kon
Matthew R. Skelton
Rodney J. Snow

Frontiers in Physiology

doi 10.3389/fphys.2014.00314

8,640 views
33 citations

Original Research

Published on 29 Apr 2025

Heterozygous females from a rat model for creatine transporter deficiency reveal altered behavioral response to stressors, normal body weight and slight metabolic changes

in Neurodevelopment

Lara Duran-Trio
Marc Lanzillo
Dunja Simicic
Clothilde Roux-Petronelli
Stephen J. Bruce
Carmen Sandi
Cristina Cudalbu
Olivier Braissant

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1520550

2,806 views

Original Research

Published on 28 Jun 2022

Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1

in Membrane Physiology and Membrane Biophysics

Clemens V. Farr
Ali El-Kasaby
Fatma A. Erdem
Sonja Sucic
Michael Freissmuth
Walter Sandtner

Frontiers in Physiology

doi 10.3389/fphys.2022.919439

3,947 views
13 citations

Brief Research Report

Published on 18 Aug 2023

Creatine supplementation enhances anti-tumor immunity by promoting adenosine triphosphate production in macrophages

in Nutritional Immunology

Zhenzi Peng
Suguru Saito

Frontiers in Immunology

doi 10.3389/fimmu.2023.1176956

32,715 views
16 citations

Brief Research Report

Published on 29 Mar 2023

Reduction in cardiolipin reduces expression of creatine transporter-1 and creatine transport in growing hCMEC/D3 human brain microvessel endothelial cells

in CNS Drug Delivery

Donald W. Miller
Grant M. Hatch

Frontiers in Drug Delivery

doi 10.3389/fddev.2023.1158369

2,765 views
1 citation

Articles

A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism

An international questionnaire highlights and supports the case for including girls in Creatine Transporter Deficiency research

Dodecyl creatine ester improves cognitive function and identifies key protein drivers including KIF1A and PLCB1 in a mouse model of creatine transporter deficiency

Epigenetic alterations in creatine transporter deficiency: a new marker for dodecyl creatine ester therapeutic efficacy monitoring

How a patient-led advocacy organization supports the road to diagnosis and treatment of creatine transporter deficiency

The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Creatine transporter (SLC6A8) knockout mice display an increased capacity for in vitro creatine biosynthesis in skeletal muscle

Heterozygous females from a rat model for creatine transporter deficiency reveal altered behavioral response to stressors, normal body weight and slight metabolic changes

Cooperative Binding of Substrate and Ions Drives Forward Cycling of the Human Creatine Transporter-1

Creatine supplementation enhances anti-tumor immunity by promoting adenosine triphosphate production in macrophages

Reduction in cardiolipin reduces expression of creatine transporter-1 and creatine transport in growing hCMEC/D3 human brain microvessel endothelial cells