ORIGINAL RESEARCH article

Front. Neurosci.

Sec. Neurodevelopment

Volume 19 - 2025 | doi: 10.3389/fnins.2025.1520550

This article is part of the Research TopicThink Rare: Current Advances on Understanding and Treatment of X-Linked Neurodevelopmental DisordersView all 4 articles

Heterozygous females from a rat model for Creatine Transporter Deficiency reveal altered behavioral response to stressors, normal body weight and slight metabolic changes

Provisionally accepted
Lara Duran-TrioLara Duran-Trio1*Marc LanzilloMarc Lanzillo1Dunja SimicicDunja Simicic2Clothilde Roux-PetronelliClothilde Roux-Petronelli1Stephen BruceStephen Bruce1Carmen SandiCarmen Sandi3Cristina CudalbuCristina Cudalbu2Olivier BraissantOlivier Braissant1*
  • 1Service of Clinical Chemistry, University of Lausanne and Lausanne University Hospital of Lausanne, Lausanne, Switzerland
  • 2Centre d’Imagerie Biomedicale (CIBM), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Geneva, Switzerland
  • 3Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Geneva, Switzerland

The final, formatted version of the article will be published soon.

Select one of your emails

You have multiple emails registered with Frontiers:

Notify me on publication

Please enter your email address:

If you already have an account, please login

You don't have a Frontiers account ? You can register here

Duran-Trio Lara: design and plan, body weight, liquids and sample extractions (and preparation to metabolites determination), data analysis, figures, first draft-writing, writing and corrections • Lanzillo Marc: liquids and sample extractions (and preparation to metabolites determination), 1 H-MRS and quantification, muscle histology and myocyte quantification, writing and corrections • Dunja: 1 H-MRS and quantification, writing and corrections • Clothilde Roux-Petronelli, Stephen J. Bruce: metabolites measure by tandem-MS • Cudalbu Cristina: 1 H-MRS, writing and corrections • Sandi Carmen: behavioral experiments support, writing and corrections • Braissant Olivier: design and plan, founding, draft-writing, writing and corrections

Keywords: 4792 (excl. abstract, bibliography, captions) Nº figures/ tables: 3 figs., 1 supp. fig, 1 supp. table

Received: 31 Oct 2024; Accepted: 24 Mar 2025.

Copyright: © 2025 Duran-Trio, Lanzillo, Simicic, Roux-Petronelli, Bruce, Sandi, Cudalbu and Braissant. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Lara Duran-Trio, Service of Clinical Chemistry, University of Lausanne and Lausanne University Hospital of Lausanne, Lausanne, Switzerland
Olivier Braissant, Service of Clinical Chemistry, University of Lausanne and Lausanne University Hospital of Lausanne, Lausanne, Switzerland

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Supplementary Material