Critical Discourse | List of Frontiers open access articles

Original Research

Published on 10 Nov 2025

A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure

in Cardiovascular and Smooth Muscle Pharmacology

Ambrish Kumar
Sarah Deloach
Lernix Williams
Donald J. DiPette
Jay D. Potts

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692472

373 views

Original Research

Published on 10 Nov 2025

Cross-disciplinary awareness of healthcare associated infections (HAIs): insights from a university-wide survey

in Healthcare Professions Education

Arianna Delicati
Dolores Catelan
Beatrice Marcante
Luciana Caenazzo
Pamela Tozzo

Frontiers in Medicine

doi 10.3389/fmed.2025.1642560

322 views

Original Research

Published on 10 Nov 2025

Decadal-scale urban footprints on seagrass blue carbon dynamics in Palk Bay, India: a remote sensing based framework

in Marine Biogeochemistry

Rajamohanan Pillai Ranith
Nandini N. Menon
E. P. Nobi
Farzana Haris
Roshin P. Raj
Lasse H. Pettersson

Frontiers in Marine Science

doi 10.3389/fmars.2025.1690700

415 views

Systematic Review

Published on 10 Nov 2025

Effect of different exercise interventions on metabolic syndrome risk factors in postmenopausal women: a network meta-analysis

in Exercise Physiology

Tongyan Zhang
Anastasiia V. Kabachkova
Zifu Deng
Yishu Liang
Meng Li
Wenxue Yuan

Frontiers in Physiology

doi 10.3389/fphys.2025.1703881

179 views

Original Research

Published on 10 Nov 2025

PHTFNet-RPM: a probabilistic hybrid network with RPM for tobacco root disease forecasting

in Machine Learning and Artificial Intelligence

Yunhong Bu
Tingshan Yao
Shaowu Geng
Renjie Huang

Frontiers in Big Data

doi 10.3389/fdata.2025.1705587

268 views

Original Research

Published on 10 Nov 2025

Association of systemic inflammatory biomarkers with prostate cancer risk: a population-based (NHANES) and clinical validation study

in Cancer Endocrinology

Guoqiang Huang
Kaiwen Xiao
Shuangquan Lin
Xiongbing Lu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1697617

355 views

Original Research

Published on 10 Nov 2025

A tumor immune microenvironment gene expression signature for predicting prognosis, immunotherapy efficacy, and drug candidates in triple-negative breast cancer

in Cancer Immunity and Immunotherapy

Li Bai
Ziyu Zhou
Qingqing Yu
Zhen Ye
Qingzhou Li
Shengrong Li
Congcong Li
Yu Hu
Yunjie Hu
Xinran Tai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1676768

404 views

Original Research

Published on 10 Nov 2025

Post-treatment to enhance the mechanical performance of printed Onyx

in Solid and Structural Mechanics

Moises Jimenez-Martinez
Julio Varela-Soriano
Rafael Carrera-Espinoza
Manuel Coca-Gonzalez

Frontiers in Mechanical Engineering

doi 10.3389/fmech.2025.1710902

187 views

Review

Published on 10 Nov 2025

Role of toll-like receptors in pulmonary immunity: mechanisms and therapeutic implications

in Inflammation

Zhuojian Qu
Zhiliang Guo
Chunjuan Yang
Xiumei Guan
Min Cheng
Pingping Wang
Donghua Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682649

Original Research

Published on 10 Nov 2025

Stereotactic body radiation therapy combined with cadonilimab and lenvatinib in the treatment of hepatocellular carcinoma with Vp3 or Vp4 portal vein tumor thrombus: a prospective, multicenter, single-arm, phase II clinical trial

in Cancer Immunity and Immunotherapy

Ning Mo
Kai Hu
Zhiming Zeng
Lihua Yang
Yeying Fang
Jie Zeng
Ye Li
Zhendong Yang
Jing Tang
Tingting Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1687344

176 views

Original Research

Published on 10 Nov 2025

Development of machine learning predictive model for type 2 diabetic retinopathy using the triglyceride-glucose index explained by SHAP method

in Clinical Diabetes

Xiaoqin Liu
Shuying Wu
Yue Yang
Yang Li
Xinting Zhang
Rihui Liu
Ling Qin
Fei Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1631647

257 views

Review

Published on 10 Nov 2025

Unveiling the gut-liver axis: the behind-the-scenes “manipulator” of human immune function

in Comparative Immunology

Peizhe Li
Yu Wang
Yanan Dong
Xin Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638197

154 views

Review

Published on 10 Nov 2025

Rewiring tumor visibility: The immunopeptidome as a dynamic interface between antigen processing, microenvironmental stress, and immune recognition

in Cancer Immunity and Immunotherapy

Kangkang Zhao
Yunlan Huang
Linlin Chang
Baiyu Wang
Mingshi Ye
Jinhong Qi

Frontiers in Oncology

doi 10.3389/fonc.2025.1691719

345 views

Original Research

Published on 10 Nov 2025

Revealing the oceanic spawning migrations of Australian long-finned eels (Anguilla reinhardtii) via satellite telemetry

in Marine Biology

Wayne M. Koster
Håkan Westerberg
David Dawson
Roland Kahsnitz
Kim Aarestrup
Ben Fanson

Frontiers in Marine Science

doi 10.3389/fmars.2025.1690502

852 views

Original Research

Published on 10 Nov 2025

Efficacy and safety of insulin degludec/aspart in patients with type 2 and type 1 diabetes mellitus: real-world evidence from Indonesia

in Clinical Diabetes

Hendra Zufry
Krishna Wardhana Sucipto
Agustia Sukri Ekadamayanti
Qanita Iqbal

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1690169

169 views

Original Research

Published on 10 Nov 2025

Pituitary hormone deficiencies in prolactinomas: prevalence, predictors, and functional recovery

in Cancer Endocrinology

Antonio Prinzi
Ginevra Fava
Ignazio Bacchi
Federica Spitali
Antonio Galvano
Giorgio Arnaldi
Francesco Frasca
Valentina Guarnotta
Pasqualino Malandrino

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1705300

186 views

Articles

A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure

Cross-disciplinary awareness of healthcare associated infections (HAIs): insights from a university-wide survey

Decadal-scale urban footprints on seagrass blue carbon dynamics in Palk Bay, India: a remote sensing based framework

Effect of different exercise interventions on metabolic syndrome risk factors in postmenopausal women: a network meta-analysis

PHTFNet-RPM: a probabilistic hybrid network with RPM for tobacco root disease forecasting

Association of systemic inflammatory biomarkers with prostate cancer risk: a population-based (NHANES) and clinical validation study

A tumor immune microenvironment gene expression signature for predicting prognosis, immunotherapy efficacy, and drug candidates in triple-negative breast cancer

Post-treatment to enhance the mechanical performance of printed Onyx

Role of toll-like receptors in pulmonary immunity: mechanisms and therapeutic implications

Stereotactic body radiation therapy combined with cadonilimab and lenvatinib in the treatment of hepatocellular carcinoma with Vp3 or Vp4 portal vein tumor thrombus: a prospective, multicenter, single-arm, phase II clinical trial

Development of machine learning predictive model for type 2 diabetic retinopathy using the triglyceride-glucose index explained by SHAP method

Unveiling the gut-liver axis: the behind-the-scenes “manipulator” of human immune function

Rewiring tumor visibility: The immunopeptidome as a dynamic interface between antigen processing, microenvironmental stress, and immune recognition

Revealing the oceanic spawning migrations of Australian long-finned eels (Anguilla reinhardtii) via satellite telemetry

Efficacy and safety of insulin degludec/aspart in patients with type 2 and type 1 diabetes mellitus: real-world evidence from Indonesia

Pituitary hormone deficiencies in prolactinomas: prevalence, predictors, and functional recovery