De Novo Organ Initiation | List of Frontiers open access articles

Original Research

Published on 13 Oct 2025

Colonization by Akkermansia muciniphila modulates central nervous system autoimmunity in an ecological context-dependent manner

in Multiple Sclerosis and Neuroimmunology

Daniel Peipert
Theresa L. Montgomery
Lucinda C. Toppen
Margaret Frances J. Lee
Matthew J. Scarborough
Dimitry N. Krementsov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655428

913 views

Original Research

Published on 13 Oct 2025

Machine learning algorithms for individualized prediction of prognosis in breast cancer liver metastases and the prognostic impact of primary tumor surgery: a multicenter study

in Cancer Endocrinology

Chunmei Chen
Jundong Wu
Bo Xu
Weiwen Li
Chengming Zhong
Zhibing Yan
Qipeng Zhong
Ronggang Li
Mingtao Shao
Yan Dong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1656191

781 views

Review

Published on 13 Oct 2025

Exosome-mediated repair of spinal cord injury: cellular sources, mechanisms of action, and combined therapeutic strategies

in Experimental Therapeutics

Zaihong Cha
Yu Li
Jianeng Pu
Yuansheng Zhang
Qixiong Lu
Wei Huang
Tao Li
Xiaoyang Lu

Frontiers in Neurology

doi 10.3389/fneur.2025.1645457

572 views

Original Research

Published on 13 Oct 2025

Analysis of the characteristics of endometrial fluid samples in recurrent pregnancy loss patients based on 16S rRNA gene sequencing technology

in Extra-intestinal Microbiome

Xiaoping Wang
Nan Ding
Xiaofeng Li
Menghao Lu
Peili Wang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1646125

566 views

Original Research

Published on 13 Oct 2025

The clinical validity of radiomics-based prediction of molecular subtypes in breast cancer from digital mammary tomosynthesis

in Breast Cancer

Jing Xue
Yilun Li
Tianyun Qu
Yidi Qin
Haoqi Wang
Xiaocui Rong
Jingliu Tian
Tao Wang
Jianhua Zhang
Zhigang Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1661116

315 views

Original Research

Published on 13 Oct 2025

Effectiveness of modified clear aligner designs in mesialization of permanent molars: a typodont model study

in Reconstructive Dentistry

Sara Mohamed Al Ali
Ahmed Ghoneima

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1645821

661 views

Original Research

Published on 13 Oct 2025

Sophora tonkinensis enhances activation of cGAS-STING pathway and restrains HBV replication

in Ethnopharmacology

Yuanyuan Guo
Jincai Wen
Xueting Wang
Xianling Wang
Yingjie Xu
Siqi Huang
Zongliang Lu
Xiaoyan Chen
Ang Huang
Zhijie Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630460

505 views

Brief Research Report

Published on 13 Oct 2025

Climate anxiety impairs sustained attention: objective evidence of a cognitive cost

in Environmental Psychology

Ekaterina Denkova
Taylor K. Tardibuono
Jason S. Tsukahara
Anthony P. Zanesco
Amishi P. Jha

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1624782

640 views

Original Research

Published on 13 Oct 2025

Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings

in Crop and Product Physiology

Mostafa M. Rady
Amr Elkelish
Nada M. Nady
Sebnem Kusvuran
Alpaslan Kusvuran
Ahmed Shaaban
Haifa A S Alhaithloul
Mohamed A. M. Ali
Abdelghafar M. Abu-Elsaoud
Tapsoba François

Frontiers in Plant Science

doi 10.3389/fpls.2025.1630537

813 views

Systematic Review

Published on 13 Oct 2025

Exploring fear in human-robot interaction: a scoping review of older adults’ experiences with social robots

in Human-Robot Interaction

Ahmed Elsheikh
Dena Al-Thani
Achraf Othman

Frontiers in Robotics and AI

doi 10.3389/frobt.2025.1626471

1,018 views

Original Research

Published on 13 Oct 2025

Physical activity partially mediating the social gradient in adolescent mental health

in Public Mental Health

Johan Dahlstrand
Qinyun Lin
Peter Friberg
Jonatan Fridolfsson
Yun Chen

Frontiers in Public Health

doi 10.3389/fpubh.2025.1622080

510 views

Original Research

Published on 13 Oct 2025

Anomaly detection and early risk identification in digital disaster response-based on deep learning in public health

in Disaster and Emergency Medicine

Wanxin Wu
Chun Pan

Frontiers in Public Health

doi 10.3389/fpubh.2025.1624345

405 views

Review

Published on 13 Oct 2025

Emerging therapeutic potential of glucagon-like Peptide-1 receptor agonists in knee osteoarthritis: a systematic review

in Experimental Pharmacology and Drug Discovery

Yapeng Li
Lanbo Yang
Feng Li
Jia Fu
Wangyu Zhao
Xiaolong Wu
Jiayi Guo
Chen Yue

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627691

535 views

Original Research

Published on 13 Oct 2025

Exploring molecular characteristics and interactions of blood stasis syndrome in ischemic heart failure by integrated multi-omics

in Molecular Diagnostics and Therapeutics

Aolong Wang
Jingjing Wei
Lijie Qiao
Xingyuan Li
Ming Li
Xinfeng Zhu
Yilin Zhang
Qifei Zhao
Rui Yu
Bin Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1627849

607 views

Original Research

Published on 13 Oct 2025

Propolis mitigates busulfan-induced testicular dysfunction in rats: insights into redox stabilization, PCNA modulation, and caspase-3 inhibition

in Ethnopharmacology

Elham A. AbdAllah
Basant A. Eid
Hassan A. Hussein
Nasser S. Abou khalil
Sohair M. M. Ragab
Asmaa Y. Wahman
Hailah M. Almohaimeed
Rehab H. Moneeb
Hanem S. Abdel-Tawab
Zuhair M. Mohammedsaleh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656541

512 views

Review

Published on 13 Oct 2025

Post-pandemic era: global trends, benefits, and barriers in integrating artificial intelligence into public health education

in Public Health Education and Promotion

Adewunmi Akingbola
Abiodun Adegbesan
Samuel Tundealao
Akpevwe Emmanuella Benson
Abdulfatai Olumide Makinde
Mayowa Shekoni
Khalid Animashaun
Tosin Fakiyesi

Frontiers in Public Health

doi 10.3389/fpubh.2025.1648970

885 views

Articles

Colonization by Akkermansia muciniphila modulates central nervous system autoimmunity in an ecological context-dependent manner

Machine learning algorithms for individualized prediction of prognosis in breast cancer liver metastases and the prognostic impact of primary tumor surgery: a multicenter study

Exosome-mediated repair of spinal cord injury: cellular sources, mechanisms of action, and combined therapeutic strategies

Analysis of the characteristics of endometrial fluid samples in recurrent pregnancy loss patients based on 16S rRNA gene sequencing technology

The clinical validity of radiomics-based prediction of molecular subtypes in breast cancer from digital mammary tomosynthesis

Effectiveness of modified clear aligner designs in mesialization of permanent molars: a typodont model study

Sophora tonkinensis enhances activation of cGAS-STING pathway and restrains HBV replication

Climate anxiety impairs sustained attention: objective evidence of a cognitive cost

Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings

Exploring fear in human-robot interaction: a scoping review of older adults’ experiences with social robots

Physical activity partially mediating the social gradient in adolescent mental health

Anomaly detection and early risk identification in digital disaster response-based on deep learning in public health

Emerging therapeutic potential of glucagon-like Peptide-1 receptor agonists in knee osteoarthritis: a systematic review

Exploring molecular characteristics and interactions of blood stasis syndrome in ischemic heart failure by integrated multi-omics

Propolis mitigates busulfan-induced testicular dysfunction in rats: insights into redox stabilization, PCNA modulation, and caspase-3 inhibition

Post-pandemic era: global trends, benefits, and barriers in integrating artificial intelligence into public health education