Dichotomous Outcomes | List of Frontiers open access articles

Mini Review

Published on 16 Nov 2022

The dichotomous outcomes of TNFα signaling in CD4+ T cells

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Nikolaos Skartsis
Leonardo M. R. Ferreira
Qizhi Tang

Frontiers in Immunology

doi 10.3389/fimmu.2022.1042622

12,931 views
6 citations

Original Research

Published on 06 Dec 2023

Dichotomous outcomes vs. survival regression models for identification of predictors of mortality among patients with severe acute respiratory illness during COVID-19 pandemics

in Infectious Diseases: Epidemiology and Prevention

Karen Ingrid Tasca
Camila Gonçalves Alves
Rejane Maria Tommasini Grotto
Leonardo Nazario de Moraes
Patrícia Akemi Assato
Carlos Magno Castelo Branco Fortaleza

Frontiers in Public Health

doi 10.3389/fpubh.2023.1271177

1,997 views

Hypothesis and Theory

Published on 11 Sep 2017

Immunological Control of Viral Infections in Bats and the Emergence of Viruses Highly Pathogenic to Humans

in Comparative Immunology

Tony Schountz
Michelle L. Baker
John Butler
Vincent Munster

Frontiers in Immunology

doi 10.3389/fimmu.2017.01098

29,270 views
137 citations

Original Research

Published on 10 Nov 2017

Odds Ratio or Prevalence Ratio? An Overview of Reported Statistical Methods and Appropriateness of Interpretations in Cross-sectional Studies with Dichotomous Outcomes in Veterinary Medicine

in Veterinary Epidemiology and Economics

Brayan Alexander Fonseca Martinez
Vanessa Bielefeldt Leotti
Gustavo de Sousa e Silva
Luciana Neves Nunes
Gustavo Machado
Luís Gustavo Corbellini

Frontiers in Veterinary Science

doi 10.3389/fvets.2017.00193

140,331 views
196 citations

Systematic Review

Published on 10 May 2023

Effectiveness and safety of multidrug therapy containing clofazimine for paucibacillary leprosy and clarithromycin for rifampicin-resistant leprosy: a systematic review and meta-analysis

in Infectious Diseases: Pathogenesis and Therapy

Thais Montezuma
Sebastian Vernal
Elaine Nascimento Andrade
Jurema Guerrieri Brandão
Gustavo Laine Araújo de Oliveira
Ciro Martins Gomes

Frontiers in Medicine

doi 10.3389/fmed.2023.1139304

6,547 views
6 citations

Systematic Review

Published on 29 Apr 2021

Effect of Huang-Lian Jie-Du Decoction on Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

in Ethnopharmacology

Zhipeng Hu
Maoyi Yang
Ya Liu
Qiyue Yang
Hongyan Xie
Sihan Peng
Juan Gao
Chunguang Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2021.648861

7,264 views
11 citations

Study Protocol

Published on 09 Jun 2023

Association between the development of bronchopulmonary dysplasia and platelet transfusion: a protocol for a systematic review and meta-analysis

in Neonatology

Roberto Chioma
Stefano Ghirardello
Krzysztof Włodarczyk
Joanna Ulan-Drozdowska
Antonio Spagarino
Marta Szumska
Klaudia Krasuska
Joanna Seliga-Siwecka
Roy K. Philip
Niazy Al Assaf

Frontiers in Pediatrics

doi 10.3389/fped.2023.1049014

2,753 views
2 citations

Systematic Review

Published on 07 Nov 2025

The effect of esketamine on postoperative delirium in patients undergoing general anesthesia: a systematic review and meta-analysis

in Neuropharmacology

Chao-Xu
Rui-Jun Tong
Qi-Hong Shen
Jing Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681531

12,893 views

Original Research

Published on 14 Apr 2021

Association of Birth Order With Mental Health Problems, Self-Esteem, Resilience, and Happiness Among Children: Results From A-CHILD Study

in Child and Adolescent Psychiatry

Yoshifumi Fukuya
Takeo Fujiwara
Aya Isumi
Satomi Doi
Manami Ochi

Frontiers in Psychiatry

doi 10.3389/fpsyt.2021.638088

131,912 views
51 citations

Systematic Review

Published on 01 Nov 2021

HIV Protease Inhibitors and Insulin Sensitivity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

in Drugs Outcomes Research and Policies

Violet Dismas Kajogoo
Mary Gorret Atim
Demeke Amare
Melka Geleta
Yilkal Muchie
Hanna Amanuel Tesfahunei
Willyhelmina Olomi
Joan Acam
Tsegahun Manyazewal

Frontiers in Pharmacology

doi 10.3389/fphar.2021.635089

6,521 views
21 citations

Systematic Review

Published on 17 Sep 2025

Perioperative immune checkpoint inhibitors in elderly patients with resectable NSCLC: a systematic review and meta-analysis

in Thoracic Oncology

Yue Cao
Yumeng Tian
Lin Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1589846

2,394 views

Systematic Review

Published on 27 Sep 2024

Atogepant for migraine prevention: a meta-analysis of safety and efficacy in adults

in Headache and Neurogenic Pain

Adarsh Raja
Rabia Asim
Muhammad Hamza Shuja
Sandesh Raja
Tazheen Saleh Muhammad
Simran Bajaj
Abdul Hadi Ansari
Hamza Ali
Iffat Ambreen Magsi
Muhammad Hammad Faridi

Frontiers in Neurology

doi 10.3389/fneur.2024.1468961

13,841 views
5 citations

Original Research

Published on 29 Oct 2021

Quantifying the Impacts of Pre- and Post-Conception TSH Levels on Birth Outcomes: An Examination of Different Machine Learning Models

in Thyroid Endocrinology

Yuantong Sun
Weiwei Zheng
Ling Zhang
Huijuan Zhao
Xun Li
Chao Zhang
Wuren Ma
Dajun Tian
Kun-Hsing Yu
Shuo Xiao

Frontiers in Endocrinology

doi 10.3389/fendo.2021.755364

5,311 views
10 citations

Systematic Review

Published on 04 Feb 2022

Effectiveness of Amiodarone in Preventing the Occurrence of Reperfusion Ventricular Fibrillation After the Release of Aortic Cross-Clamp in Open-Heart Surgery Patients: A Meta-Analysis

in Cardiovascular Surgery

Li-min He
An Zhang
Bin Xiong

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2022.821938

4,389 views
4 citations

Systematic Review

Accepted on 13 Feb 2026

Neoadjuvant Chemoradiotherapy With or Without PD-1 Inhibitors in MMR‑Proficient Non‑Metastatic Rectal Cancer: A Meta-Analysis of Randomized Controlled Trials

in Cancer Immunity and Immunotherapy

Yuegang Li
Chengcheng Han
Jianqiang Tang

Frontiers in Immunology

Systematic Review

Published on 09 Apr 2021

Glucagon-Like Peptide-1 Receptor Agonists for Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: A Meta-Analysis

in Clinical Diabetes

Chloe Wong
Ming Hui Lee
Clyve Yu Leon Yaow
Yip Han Chin
Xin Lei Goh
Cheng Han Ng
Amanda Yuan Ling Lim
Mark Dhinesh Muthiah
Chin Meng Khoo

Frontiers in Endocrinology

doi 10.3389/fendo.2021.609110

19,020 views
81 citations

Articles

The dichotomous outcomes of TNFα signaling in CD4+ T cells

Dichotomous outcomes vs. survival regression models for identification of predictors of mortality among patients with severe acute respiratory illness during COVID-19 pandemics

Immunological Control of Viral Infections in Bats and the Emergence of Viruses Highly Pathogenic to Humans

Odds Ratio or Prevalence Ratio? An Overview of Reported Statistical Methods and Appropriateness of Interpretations in Cross-sectional Studies with Dichotomous Outcomes in Veterinary Medicine

Effectiveness and safety of multidrug therapy containing clofazimine for paucibacillary leprosy and clarithromycin for rifampicin-resistant leprosy: a systematic review and meta-analysis

Effect of Huang-Lian Jie-Du Decoction on Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Association between the development of bronchopulmonary dysplasia and platelet transfusion: a protocol for a systematic review and meta-analysis

The effect of esketamine on postoperative delirium in patients undergoing general anesthesia: a systematic review and meta-analysis

Association of Birth Order With Mental Health Problems, Self-Esteem, Resilience, and Happiness Among Children: Results From A-CHILD Study

HIV Protease Inhibitors and Insulin Sensitivity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Perioperative immune checkpoint inhibitors in elderly patients with resectable NSCLC: a systematic review and meta-analysis

Atogepant for migraine prevention: a meta-analysis of safety and efficacy in adults

Quantifying the Impacts of Pre- and Post-Conception TSH Levels on Birth Outcomes: An Examination of Different Machine Learning Models

Effectiveness of Amiodarone in Preventing the Occurrence of Reperfusion Ventricular Fibrillation After the Release of Aortic Cross-Clamp in Open-Heart Surgery Patients: A Meta-Analysis

Neoadjuvant Chemoradiotherapy With or Without PD-1 Inhibitors in MMR‑Proficient Non‑Metastatic Rectal Cancer: A Meta-Analysis of Randomized Controlled Trials

Glucagon-Like Peptide-1 Receptor Agonists for Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: A Meta-Analysis