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Original Research

Published on 22 Oct 2025

Transcriptomic profiling during normothermic machine perfusion of human kidneys reveals a pro-inflammatory cellular landscape and gene expression signature associated with severe ischemia-reperfusion injury and delayed graft function

in Alloimmunity and Transplantation

  • Harry V. M. Spiers
  • Sarah A. Hosgood
  • Miguel Larraz
  • Lukas J. K. Stadler
  • Ying Zhai
  • Haeun Moon
  • Serena MacMillan
  • Anna Paterson
  • Michael L. Nicholson
  • Irina Mohorianu
Frontiers in Immunology
doi 10.3389/fimmu.2025.1679251
  • 2,166 views