Drug Design And Development | List of Frontiers open access articles

Review

Published on 06 Oct 2025

Immunohistochemistry in intrahepatic cholangiocarcinoma: histological subtyping and drug selection

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Han Wang
Miao-Xia He
Wen-Ming Cong
Hui Dong

Frontiers in Oncology

doi 10.3389/fonc.2025.1653534

852 views

Original Research

Published on 06 Oct 2025

Multiparametric magnetic resonance imaging-based comprehensive model on prediction of lymphovascular space invasion in cervical cancer

in Cancer Imaging and Image-directed Interventions

Tao Yang
Qinqin Yi
Jingshan Gong

Frontiers in Oncology

doi 10.3389/fonc.2025.1578119

646 views

Clinical Trial

Published on 06 Oct 2025

Effect of a community-based lifestyle intervention on predictors of behavior change regarding a healthy plant-based diet—The Healthy Lifestyle Community Program (cohort 2)

in Public Health and Nutrition

Carmen Kettler
Ragna-Marie Weber
Corinna Anand
Sarah Husain
Christian Koeder
Nora Schoch
Maren M. Michaelsen
Tobias Esch
Heike Englert

Frontiers in Public Health

doi 10.3389/fpubh.2025.1560376

875 views

Original Research

Published on 06 Oct 2025

A pseudo-ketogenic sugar-ghee-enriched diet induces metabolic and immune alterations in rats: a model of flawed ketogenic diet practice

in Animal Nutrition and Metabolism

Farah Ismail
Mohammad Khalifeh
Wael Hananeh
Batool Khataybeh
Rasha Al-Azaizeh
Muath Q. Al-Ghadi

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1582086

447 views

Systematic Review

Published on 06 Oct 2025

Clinical efficacy of fecal microbiota transplantation in alleviating depressive symptoms: a meta-analysis of randomized trials

in Mood Disorders

Xiaotao Zhang
Ying Li
Yueyue Guo
Jia Sun
Yang Yang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1656969

481 views

Original Research

Published on 06 Oct 2025

Morning serum cortisol as a predictor of synacthen stimulation test outcomes during corticosteroid withdrawal: a comparative analysis of high-dose and low-dose protocols

in Adrenal Endocrinology

Leonard Saiegh
Balsam Dakwar
Katya Jovanovic
Ilana Rosenblat
Muaweya Mahamed
Mohammad Sheikh Ahmad

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1655146

758 views

Original Research

Published on 06 Oct 2025

Genomic profiles of Pyricularia oryzae in Sub-Saharan Africa: exploring population differences and their evolutionary implications in the region

in Plant Pathogen Interactions

Geoffrey Onaga
Worrawit Suktrakul
Margaret Wanjiku
Ian Lorenzo Quibod
Jean-Baka Domelevo Entfellner
Joseph Bigirimana
Georges Habarugira
Rosemary Murori
Godfrey Asea
Hamidatou Euridice Tella

Frontiers in Plant Science

doi 10.3389/fpls.2025.1650532

456 views

Original Research

Published on 06 Oct 2025

Alpine steppe degradation weakens ecosystem multifunctionality through the decline in climax dominant species on the Qinghai-Tibetan plateau

in Functional Plant Ecology

Xiao-Yun Wang
Yuan-Ming Xiao
Wen-Ying Wang
Xin-Yu Yang
Guo-Ying Zhou

Frontiers in Plant Science

doi 10.3389/fpls.2025.1650352

1,080 views

Original Research

Published on 06 Oct 2025

Futarchy in decentralized science: empirical and simulation evidence for outcome-based conditional markets in DeSci DAOs

in Blockchain Technologies

L. Weidener
S. Shilina

Frontiers in Blockchain

doi 10.3389/fbloc.2025.1650188

527 views

Original Research

Published on 06 Oct 2025

Immune regulatory mechanisms of M2 macrophage polarization and efferocytosis in diabetic kidney disease: an integrated screening study with therapeutic implications

in Renal Endocrinology

Yi Kang
Qian Jin
Mengqi Zhou
Huijuan Zheng
Danwen Li
Xuezhe Wang
Jingwei Zhou
Jie Lv
Yaoxian Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1652402

357 views

Core Concept

Published on 06 Oct 2025

Solving Cystic Fibrosis: From lab Bench to Bedside

in Human Health

Michael J. Welsh
Paul Negulescu

Frontiers for Young Minds

doi 10.3389/frym.2025.1650140

197 views

Original Research

Published on 06 Oct 2025

Generalised machine learning models outperform personalised models for cognitive load classification in real-life settings

in Digital Mental Health

Christoph Anders
Ipsita Bhaduri
Bert Arnrich

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1650085

896 views

Original Research

Published on 06 Oct 2025

Within-reef biomass partitioning in a Mediterranean vermetid reef: a baseline for future monitoring

in Marine Biology

Francesco Paolo Mancuso
Luca Bisanti
Flavio Picone
Renato Chemello

Frontiers in Marine Science

doi 10.3389/fmars.2025.1656826

907 views

Original Research

Published on 06 Oct 2025

Prediction of lymphovascular invasion in non-mass enhancement breast cancer using DCE-MRI and clinical-pathological features

in Breast Cancer

Shiqi Guo
Kai Zhao
Hu Xu
Yujiao Xie
Qingyang Li
Junqing Liang
Siyi Chen
Jiahong Sun
Zhaofeng Gao
Li Zhu

Frontiers in Oncology

doi 10.3389/fonc.2025.1539748

318 views

Systematic Review

Published on 06 Oct 2025

Precision agriculture techniques for optimizing chemical fertilizer use and environmental sustainability: a systematic review

in Agroecological Cropping Systems

Baozhong Cai
Fang Shi
Betelhem A. Geremew
Amsalu K. Addis
Meseret C. Abate
Wubliker Dessie
Tesfaye Bayu

Frontiers in Agronomy

doi 10.3389/fagro.2025.1665444

582 views

Review

Published on 06 Oct 2025

Unspoken words: decoding the dialog between type 2 innate lymphoid cells and T cells

in NK and Innate Lymphoid Cell Biology

Zahra Jamila Ikra
Qiutong Huang
Huiyang Yu
Gabrielle T. Belz
Craig N. Jenne
Nicolas Jacquelot

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677358

3,023 views

Articles

Immunohistochemistry in intrahepatic cholangiocarcinoma: histological subtyping and drug selection

Multiparametric magnetic resonance imaging-based comprehensive model on prediction of lymphovascular space invasion in cervical cancer

Effect of a community-based lifestyle intervention on predictors of behavior change regarding a healthy plant-based diet—The Healthy Lifestyle Community Program (cohort 2)

A pseudo-ketogenic sugar-ghee-enriched diet induces metabolic and immune alterations in rats: a model of flawed ketogenic diet practice

Clinical efficacy of fecal microbiota transplantation in alleviating depressive symptoms: a meta-analysis of randomized trials

Morning serum cortisol as a predictor of synacthen stimulation test outcomes during corticosteroid withdrawal: a comparative analysis of high-dose and low-dose protocols

Genomic profiles of Pyricularia oryzae in Sub-Saharan Africa: exploring population differences and their evolutionary implications in the region

Alpine steppe degradation weakens ecosystem multifunctionality through the decline in climax dominant species on the Qinghai-Tibetan plateau

Futarchy in decentralized science: empirical and simulation evidence for outcome-based conditional markets in DeSci DAOs

Immune regulatory mechanisms of M2 macrophage polarization and efferocytosis in diabetic kidney disease: an integrated screening study with therapeutic implications

Solving Cystic Fibrosis: From lab Bench to Bedside

Generalised machine learning models outperform personalised models for cognitive load classification in real-life settings

Within-reef biomass partitioning in a Mediterranean vermetid reef: a baseline for future monitoring

Prediction of lymphovascular invasion in non-mass enhancement breast cancer using DCE-MRI and clinical-pathological features

Precision agriculture techniques for optimizing chemical fertilizer use and environmental sustainability: a systematic review

Unspoken words: decoding the dialog between type 2 innate lymphoid cells and T cells