Intrusiveness | List of Frontiers open access articles

Original Research

Published on 08 Oct 2025

Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework

in Regulatory Toxicology

Jessica Ryman
Richard A. Becker

Frontiers in Toxicology

doi 10.3389/ftox.2025.1657708

922 views

Review

Published on 08 Oct 2025

Unraveled role of TLR7-mediated interferon signaling activation in COVID-19

in Clinical Infectious Diseases

Junjian Xue
Xiaoyin Wang
Hui Wang
Bin Qiao
Pengfei Gao
Bin Ren
Shushan Yan

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1658249

403 views

Original Research

Published on 08 Oct 2025

Leak detection in water supply networks using inverse transient analysis in time and frequency domain: a comparative investigation

in Water and Built Environment

Hadi Ranginkaman
Amin E. Bakhshipour
Ali Haghighi
Sven O. Krumke
Ulrich Dittmer

Frontiers in Water

doi 10.3389/frwa.2025.1661148

476 views

Original Research

Published on 08 Oct 2025

Integrative clinical and molecular insights into the comorbidity between depression and sleep apnea syndrome

in Behavioral and Psychiatric Genetics

HaiHua Chen
LanMei Zhuang
ZhiJuan Ji
Xing Sun
Ting Zhu
Bo Wang
Jin Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1659330

3,173 views

Original Research

Published on 08 Oct 2025

Hypo-osmotic stress is an anticipatory trigger of heat-resistance in presumptive extraintestinal pathogenic Escherichia coli isolated from treated sewage

in Infectious Agents and Disease

Kanghee Ryu
Daniel Yu
Paul Stothard
Simon J. G. Otto
Michael Gänzle
Norma J. Ruecker
Norman F. Neumann

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1676613

628 views

Original Research

Published on 08 Oct 2025

Stroke rate–stroke length dynamics in elite freestyle swimming: application of kernel density estimation

in Elite Sports and Performance Enhancement

Craig A. Staunton
Jesús J. Ruiz-Navarro
Dennis-Peter Born

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1656633

615 views

Original Research

Published on 08 Oct 2025

Genomic characterisation of the metal tolerance protein gene family and elucidation of functional role in heavy metal tolerance and accumulation in Coptis chinensis

in Plant Abiotic Stress

Yi Zhang
Lili Wang
Jinke Zhang
Chenxi Wang
Yue Fan
Haohao Cao
Huanyu Zhang
Yuchen Ma
Haoyu Wang
Jiaxin Kang

Frontiers in Plant Science

doi 10.3389/fpls.2025.1658134

210 views

Original Research

Published on 08 Oct 2025

EEG synchronization signatures for decoding attentional states during continuous force control

in Brain Imaging Methods

Yilei Zheng
Qiaoxiu Wang
Qianqian Tong
Bohao Tian
Peng Su
Yonghong Xu
Dangxiao Wang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1654827

582 views

Review

Published on 08 Oct 2025

Neuro–immune–tumor axis in gliomas: a review of mechanisms, models, and translational opportunities

in Cancer Immunity and Immunotherapy

Lu Xu
Shuangyu Chen
Yixin Fu
Tingting Zhou
Jianghao Yu
Jiayang Li
Wei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682322

307 views

Original Research

Published on 08 Oct 2025

Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response

in Ethnopharmacology

Tong Luo
Ai Liya
Feng Wang
Wei Yan
Saiyin Chaoketu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682523

276 views

Original Research

Published on 08 Oct 2025

Linking the heart and brain in type 2 diabetes: association between global longitudinal strain and cognitive function

in Clinical Diabetes

Federica Barutta
Alessandro Andreis
Martina Bollati
Arianna Ferro
Stefania Bellini
Giulia Gioiello
Giulio Mengozzi
Matteo Bellettini
Gaetano M. De Ferrari
Gianluca Alunni

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1689792

302 views

Correction

Published on 08 Oct 2025

Correction: Multiple fungi may connect the roots of an orchid (Cypripedium reginae) and ash (Fraxinus nigra) in western Newfoundland

in Fungi-Plant Interactions

Nimalka M. Weerasuriya
Katarina Kukolj
Rebecca Spencer
Dmitry Sveshnikov
R. Greg Thorn

Frontiers in Fungal Biology

doi 10.3389/ffunb.2025.1691090

432 views

Original Research

Published on 08 Oct 2025

Long-term trends and future projections of the burden of diabetic nephropathy in China: a comprehensive analysis of GBD data from 1990 to 2036

in Clinical Diabetes

Yan Zhang
Dong Hou
Zihui Chai
Xizi Li
Chuchu Shan
Yuetong Zhao
Siyuan Song
Ying Tan
Jiangyi Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1681689

251 views

Original Research

Published on 08 Oct 2025

Macrophage PTP1B regulates mitochondrial dynamics via the JAK2/STAT3-OPA1 axis and activates the cGAS/STING signaling pathway

in Inflammation

Xuefeng Lei
Diandian Qian
Wenzheng Zhang
Bin’an Zhao
Yabin Li
Hua Hao
Jing Yuan
Le Zhao
Centao Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644289

438 views

Original Research

Published on 08 Oct 2025

Evaluating observed and perceived experiences of operating room to paediatric critical care unit handoffs: an initial assessment to inform quality improvement

in Pediatric Critical Care

Jacob Davidson
Emily Walser
Evelyn V. Waugh
Claire A. Wilson
Julie Strychowsky
Janice Tijssen
Abhijit Biswas
Jennifer Y. Lam

Frontiers in Pediatrics

doi 10.3389/fped.2025.1644064

547 views

Original Research

Published on 08 Oct 2025

Diagnostic consistency of GLIM criteria and PG-SGA for malnutrition in patients with pancreatic cancer

in Clinical Nutrition

Feifei Wang
Cong Wang
Liwei Zhang
Xiuli Li

Frontiers in Nutrition

doi 10.3389/fnut.2025.1642171

447 views

Articles

Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework

Unraveled role of TLR7-mediated interferon signaling activation in COVID-19

Leak detection in water supply networks using inverse transient analysis in time and frequency domain: a comparative investigation

Integrative clinical and molecular insights into the comorbidity between depression and sleep apnea syndrome

Hypo-osmotic stress is an anticipatory trigger of heat-resistance in presumptive extraintestinal pathogenic Escherichia coli isolated from treated sewage

Stroke rate–stroke length dynamics in elite freestyle swimming: application of kernel density estimation

Genomic characterisation of the metal tolerance protein gene family and elucidation of functional role in heavy metal tolerance and accumulation in Coptis chinensis

EEG synchronization signatures for decoding attentional states during continuous force control

Neuro–immune–tumor axis in gliomas: a review of mechanisms, models, and translational opportunities

Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response

Linking the heart and brain in type 2 diabetes: association between global longitudinal strain and cognitive function

Correction: Multiple fungi may connect the roots of an orchid (Cypripedium reginae) and ash (Fraxinus nigra) in western Newfoundland

Long-term trends and future projections of the burden of diabetic nephropathy in China: a comprehensive analysis of GBD data from 1990 to 2036

Macrophage PTP1B regulates mitochondrial dynamics via the JAK2/STAT3-OPA1 axis and activates the cGAS/STING signaling pathway

Evaluating observed and perceived experiences of operating room to paediatric critical care unit handoffs: an initial assessment to inform quality improvement

Diagnostic consistency of GLIM criteria and PG-SGA for malnutrition in patients with pancreatic cancer