Lead Discovery | List of Frontiers open access articles

Original Research

Published on 16 Feb 2026

Chemogenetic Schwann cell activation impairs early myelination and triggers adult demyelination in the peripheral nervous system

in Cellular Neurophysiology

Jazmin G. Corral
Veronica T. Cheli
Diara A. Santiago-Gonzalez
Karishma G. Kedari
Pablo M. Paez

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2026.1771951

398 views

Original Research

Published on 16 Feb 2026

Transcriptomics and non-targeted metabolomics reveal the mechanisms of leaf color changes in red-leaf cotton under drought stress and rewatering

in Plant Abiotic Stress

Hu Zhang
Jinsheng Wang
Wenju Gao
Xiangyan Ma
Hongbin Wang
Wen Zhang
Qingtao Zeng
Jianping Li
Quanjia Chen
Qin Chen

Frontiers in Plant Science

doi 10.3389/fpls.2026.1766818

197 views

Original Research

Published on 16 Feb 2026

Association between ambulatory blood pressure monitoring parameters and left ventricular hypertrophy in an Ecuadorian population

in Precision Medicine

Patricia Delgado Cedeño
José Espinoza-Plaza
Estefanía Arteaga Herrera
Joao Tumbaco Mite
Killen H. Briones Zamora
Killen H. Briones Claudett

Frontiers in Medicine

doi 10.3389/fmed.2026.1767168

253 views

Editorial

Published on 16 Feb 2026

Editorial: Integrating genetics and proteomics for drug discovery

in Pharmacogenetics and Pharmacogenomics

Karunakaran Kalesh
Liang Xue

Frontiers in Genetics

doi 10.3389/fgene.2026.1806492

331 views

Editorial

Published on 16 Feb 2026

Editorial: Exploration of marine microorganisms for sustainable biotechnology

in Microbiotechnology

Jinwei Zhang
Leonel Pereira
Runying Zeng

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1796375

247 views

Specialty Grand Challenge

Published on 16 Feb 2026

Revisiting the grand challenges: the road travelled and ahead at the frontiers of computer-aided drug design

in In silico Methods and Artificial Intelligence for Drug Discovery

José L. Medina-Franco

Frontiers in Drug Discovery

doi 10.3389/fddsv.2026.1780834

227 views

Perspective

Published on 16 Feb 2026

Chrono-immunotherapy’s current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits

in Cancer Immunity and Immunotherapy

Daiwei Liu
Zhanlin Li
Huijuan Cui
Hua Zhang
Hai Li
Xiaoyuan Wu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1777437

188 views

Mini Review

Published on 16 Feb 2026

Trauma and economic displacement: psychological consequences and interventions among Venezuelan refugees in the Americas

in Public Mental Health

Gabriel Andrade
Maha Dahawi

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1789270

212 views

Editorial

Published on 16 Feb 2026

Editorial: Advances in ecoacoustics, volume II

in Population, Community, and Ecosystem Dynamics

Almo Farina
Tim C. Mullet

Frontiers in Ecology and Evolution

doi 10.3389/fevo.2026.1791557

156 views

Editorial

Published on 16 Feb 2026

Editorial: Women in cardiovascular epidemiology and prevention

in Cardiovascular Epidemiology and Prevention

Stefania Triunfo
Angela Sciacqua

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1791590

151 views

Retraction

Published on 16 Feb 2026

Retraction: Toward a thermodynamic theory of evolution: a theoretical perspective on information entropy reduction and the emergence of complexity

in Complex Systems Theory

Frontiers in Complex Systems

doi 10.3389/fcpxs.2026.1808241

Correction

Published on 16 Feb 2026

Correction: Revealing urban-rural sustainability dynamics based on multi-source data and machine learning: spatio-temporal hotspots, driving mechanisms, and non-linear thresholds in Suzhou, China

in Land Use Dynamics

Wenquan Gan
Haoqi Wang
Pengcheng Li
Jiana Liu
Jinliu Chen

Frontiers in Environmental Science

doi 10.3389/fenvs.2026.1797731

Opinion

Published on 16 Feb 2026

Global regulatory collaboration for the assessment of lenacapavir as a long-acting pre-exposure prophylaxis against HIV infection

in Infectious Diseases: Epidemiology and Prevention

Hendy Kristyanto
María Isabel González-Tomé
Viktor Vlcek
Filip Josephson
Patrick Vrijlandt
Nicholas Perombelon

Frontiers in Public Health

doi 10.3389/fpubh.2026.1760130

386 views

Systematic Review

Published on 16 Feb 2026

The association between early-life respiratory infections and childhood asthma: a meta-analytic perspective

in Pulmonary Medicine

Rong Zhao

Frontiers in Medicine

doi 10.3389/fmed.2026.1751843

245 views

Case Report

Published on 16 Feb 2026

Acute promyelocytic leukemia with a novel TTMV::RARA fusion initially presenting as vertebral myeloid sarcoma: a case report

in Hematologic Malignancies

Li Ruijia
Zhang Qianqian
Li Xiaohong
Yang Sen
Zhang Nan
Li Jing

Frontiers in Oncology

doi 10.3389/fonc.2026.1752011

139 views

Original Research

Published on 16 Feb 2026

Isolation and identification of Pseudoxanthomonas winnipegensis from blood culture by MALDI-MS

in Bacteria and Host

Satomi Takei
Tatsuya Nagasawa
Yuji Sekiguchi
Junya Fujimura
Kanae Teramoto
Mitsuru Wakita
Teruo Kirikae
Yuki Uehara
Tatsuya Tada
Yoko Tabe

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1755501

283 views

Articles

Chemogenetic Schwann cell activation impairs early myelination and triggers adult demyelination in the peripheral nervous system

Transcriptomics and non-targeted metabolomics reveal the mechanisms of leaf color changes in red-leaf cotton under drought stress and rewatering

Association between ambulatory blood pressure monitoring parameters and left ventricular hypertrophy in an Ecuadorian population

Editorial: Integrating genetics and proteomics for drug discovery

Editorial: Exploration of marine microorganisms for sustainable biotechnology

Revisiting the grand challenges: the road travelled and ahead at the frontiers of computer-aided drug design

Chrono-immunotherapy’s current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits

Trauma and economic displacement: psychological consequences and interventions among Venezuelan refugees in the Americas

Editorial: Advances in ecoacoustics, volume II

Editorial: Women in cardiovascular epidemiology and prevention

Retraction: Toward a thermodynamic theory of evolution: a theoretical perspective on information entropy reduction and the emergence of complexity

Correction: Revealing urban-rural sustainability dynamics based on multi-source data and machine learning: spatio-temporal hotspots, driving mechanisms, and non-linear thresholds in Suzhou, China

Global regulatory collaboration for the assessment of lenacapavir as a long-acting pre-exposure prophylaxis against HIV infection

The association between early-life respiratory infections and childhood asthma: a meta-analytic perspective

Acute promyelocytic leukemia with a novel TTMV::RARA fusion initially presenting as vertebral myeloid sarcoma: a case report

Isolation and identification of Pseudoxanthomonas winnipegensis from blood culture by MALDI-MS