Learning Goals | List of Frontiers open access articles

Original Research

Published on 31 Jul 2025

Mechanically induced development and maturation of 3D in-vitro organoid platform: an organotypic heterogeneous microphysiological model of patient-derived organoids with ER/PR/HER2+ breast cancer

in Cancer Immunity and Immunotherapy

Mamta Kumari
Kamare Alam
Anamitra Bhattacharya
Nakka Sharmila Roy
Vaishnavi Madhasu
Bitan Guchhait
Sangita Dan
Soma Sett
Jayanta Chakrabarti
Chandan Mandal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594405

740 views

Original Research

Published on 31 Jul 2025

LiaS gene from two-component system is essential for caries pathogenicity in dual-species biofilms of Streptococcus mutans and Candida albicans

in Microbial Symbioses

Yanfan Cao
Yu Zeng
Yuze Yang
Guowu Gan
Shuai Chen
Xiaojing Huang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1612841

429 views

Original Research

Published on 31 Jul 2025

Deep learning-based time series prediction in multispectral and hyperspectral imaging for cancer detection

in Pathology

Lijun Hao
Changmin Wang
Jinshan Che
Mingming Sun
Yuhong Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1605865

496 views

Original Research

Published on 31 Jul 2025

Multiscale pore damage evolution and self-inhibition mechanism in rock after dynamic impact: a coupled statistical constitutive model integrating loading effects

in Petrology

Haicheng She
Yanxu Liang
Siqi Liu
Zaiqiang Hu

Frontiers in Earth Science

doi 10.3389/feart.2025.1586934

299 views

Original Research

Published on 31 Jul 2025

Enhancing prognostic accuracy in sepsis: a modified SOFA score incorporating lymphocyte count as an immune function marker

in Clinical Infectious Diseases

Zhishan Huang
Ying Cui
Chen Zhang
Huijie Yu
Lina Chen
Xingxing Wang
Jiancang Zhou
Peng Lan

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1593589

317 views

Original Research

Published on 31 Jul 2025

Linking intrinsic brain dysfunction to behavioral outcomes in combat-exposed males with PTSD symptoms

in Anxiety and Stress Disorders

Deborah L. Harrington
Qian Shen
Annemarie Angeles-Quinto
Sharon Nichols
Tao Song
Hayden Hansen
Kate A. Yurgil
Roland R. Lee
Dewleen G. Baker
Ming-Xiong Huang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1591938

245 views

Original Research

Published on 31 Jul 2025

Clinical analysis of 25 cases of infant umbilical granuloma treated with topical application of common salt granules

in Neonatology

Jingfeng Bao
Hailin Li
Donghai Yu
Ling Jiang
Yaqiang Hong

Frontiers in Pediatrics

doi 10.3389/fped.2025.1592198

277 views

Original Research

Published on 31 Jul 2025

Comprehensive data aleatory uncertainty propagation in regression random forest using a Monte Carlo approach: a struggle with incomplete data provision using a case study on probabilistic soil moisture regionalization

in Environmental Informatics and Remote Sensing

Hendrik Paasche
Ségolène Dega
Martin Schrön
Peter Dietrich

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1599320

274 views

Review

Published on 31 Jul 2025

The role of the microbiome on immune homeostasis of the host nervous system

in Microbial Immunology

Shaojuan Zhao
Danlei Fu
Yin Lin
Xiaoya Sun
Xiaokang Wang
Xuanzhen Wu
Xuejiao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609960

332 views

Original Research

Published on 31 Jul 2025

Hydrodynamic activities and lifestyle preferences synergistically drive prokaryotic community assembly processes in the dual fronts system of the Yangtze River Estuary

in Aquatic Microbiology

Han Lu
Zhonglin Ma
Lei Su
Yunfei Du
Kun Zhou
Peng Wang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1610617

556 views

Original Research

Published on 31 Jul 2025

Global, regional, and national burden of multiple myeloma, 1990 to 2021 and predictions to 2035: an analysis of the Global Burden of Disease Study 2021

in Hematology

Xin Miao
ZhaoXian Wang
HanYu Wang
XiaoYu Zeng
JiaHao Wang
Bing Luo
Ye Yang
JiaFu Yang
Lu Zhao

Frontiers in Medicine

doi 10.3389/fmed.2025.1609692

279 views

Original Research

Published on 31 Jul 2025

Plant responses and rhizosphere soil characteristics of sea-buckthorn from different sex combinations in an abandoned lead-zinc mine

in Plant Abiotic Stress

Tingjiang Gan
Zhenxiong Zeng
Wenhao Pei
Qi Jia
Yunxiao He
Juan Chen

Frontiers in Plant Science

doi 10.3389/fpls.2025.1601834

391 views

Brief Research Report

Published on 31 Jul 2025

Effective strategies for teachers to guide children’s art activities: based on a survey of children’s art activities and teacher guidance, and an analysis of their correlation

in Educational Psychology

Han Zhang
Yifan Yang
Jialin Li

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1600401

344 views

Systematic Review

Published on 31 Jul 2025

Exploring the clinical effects of Andrographis paniculata-derived compounds, its extract, or derivatives for the treatment of COVID-19: a systematic review and meta-analysis

in Pharmacology of Infectious Diseases

Peerapong Prabhakornritta
Neti Waranuch
Anjana Fuangchan
Kantapich Srikham
Kansak Boonpattharatthiti
Cindy Barnig
Siwaporn Boonyasuppayakorn
Tasana Pitaksuteepong
Parvapan Bhattarakosol
Brice Moulari

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598255

260 views

Original Research

Published on 31 Jul 2025

Comprehensive measurement of purines in biological samples

in Biomedical Analysis and Diagnostics

Rong Fu
Diane J. Sutcliffe
Ashok R. Dinasarapu
Ellen J. Hess
H. A. Jinnah

Frontiers in Analytical Science

doi 10.3389/frans.2025.1600781

340 views

Original Research

Published on 31 Jul 2025

Reference percentiles for evaluating phase angle using bioelectrical impedance analysis in Chinese children aged 6–11 years

in Clinical Nutrition

Jiongxian Yang
Yue Qian
Xiping Gu
Yue Li
Chenlu Yang
Aimin Liang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1597087

370 views

Articles

Mechanically induced development and maturation of 3D in-vitro organoid platform: an organotypic heterogeneous microphysiological model of patient-derived organoids with ER/PR/HER2+ breast cancer

LiaS gene from two-component system is essential for caries pathogenicity in dual-species biofilms of Streptococcus mutans and Candida albicans

Deep learning-based time series prediction in multispectral and hyperspectral imaging for cancer detection

Multiscale pore damage evolution and self-inhibition mechanism in rock after dynamic impact: a coupled statistical constitutive model integrating loading effects

Enhancing prognostic accuracy in sepsis: a modified SOFA score incorporating lymphocyte count as an immune function marker

Linking intrinsic brain dysfunction to behavioral outcomes in combat-exposed males with PTSD symptoms

Clinical analysis of 25 cases of infant umbilical granuloma treated with topical application of common salt granules

Comprehensive data aleatory uncertainty propagation in regression random forest using a Monte Carlo approach: a struggle with incomplete data provision using a case study on probabilistic soil moisture regionalization

The role of the microbiome on immune homeostasis of the host nervous system

Hydrodynamic activities and lifestyle preferences synergistically drive prokaryotic community assembly processes in the dual fronts system of the Yangtze River Estuary

Global, regional, and national burden of multiple myeloma, 1990 to 2021 and predictions to 2035: an analysis of the Global Burden of Disease Study 2021

Plant responses and rhizosphere soil characteristics of sea-buckthorn from different sex combinations in an abandoned lead-zinc mine

Effective strategies for teachers to guide children’s art activities: based on a survey of children’s art activities and teacher guidance, and an analysis of their correlation

Exploring the clinical effects of Andrographis paniculata-derived compounds, its extract, or derivatives for the treatment of COVID-19: a systematic review and meta-analysis

Comprehensive measurement of purines in biological samples

Reference percentiles for evaluating phase angle using bioelectrical impedance analysis in Chinese children aged 6–11 years

Reference percentiles for evaluating phase angle using bioelectrical impedance analysis in Chinese children aged 6–11 years