Lentiviral Vector | List of Frontiers open access articles

Original Research

Published on 26 Jun 2024

Degradation of specific glycosaminoglycans improves transfection efficiency and vector production in transient lentiviral vector manufacturing processes

in Bioprocess Engineering

Thomas Williams-Fegredo
Lee Davies
Carol Knevelman
Kyriacos Mitrophanous
James Miskin
Qasim A. Rafiq

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1409203

3,877 views
2 citations

Original Research

Published on 13 Nov 2023

Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations

in Primary Immunodeficiencies

Maria Carmina Castiello
Martina Di Verniere
Elena Draghici
Elena Fontana
Sara Penna
Lucia Sereni
Alessandra Zecchillo
Denise Minuta
Paolo Uva
Marco Zahn

Frontiers in Immunology

doi 10.3389/fimmu.2023.1268620

5,874 views
4 citations

Original Research

Published on 15 Nov 2018

Long-Term Labeling of Hippocampal Neural Stem Cells by a Lentiviral Vector

in Neuroplasticity and Development

Hoonkyo Suh
Qi-Gang Zhou
Irene Fernandez-Carasa
Gregory Dane Clemenson
Meritxell Pons-Espinal
Eun Jeoung Ro
Mercè Marti
Angel Raya
Fred H. Gage
Antonella Consiglio

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2018.00415

7,548 views
13 citations

Original Research

Published on 06 Jul 2018

Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15II in Murine Model

in Vaccines and Molecular Therapeutics

Lei Liu
Mengmeng Jin
Qing Tao
Li Yu
Jian Du
Cong Wang
Qingli Luo
Tian Xing
Yuanhong Xu
Jilong Shen

Frontiers in Immunology

doi 10.3389/fimmu.2018.01572

5,768 views
13 citations

Original Research

Published on 05 Feb 2018

Integrase Defective Lentiviral Vector as a Vaccine Platform for Delivering Influenza Antigens

in Vaccines and Molecular Therapeutics

Alessandra Gallinaro
Martina Borghi
Roberta Bona
Felicia Grasso
Laura Calzoletti
Laura Palladino
Serena Cecchetti
Maria Fenicia Vescio
Daniele Macchia
Valeria Morante

Frontiers in Immunology

doi 10.3389/fimmu.2018.00171

8,579 views
46 citations

Original Research

Published on 21 Feb 2025

Transduction of hematopoietic stem and progenitor cells by an MECP2 lentiviral vector improves Rett syndrome phenotypes

in Neurological Drugs

Joseph S. Anderson
Jill L. Silverman
Alyse L. Lodigiani
Camilla M. Barbaduomo
Julie R. Beegle

Frontiers in Drug Discovery

doi 10.3389/fddsv.2025.1545391

2,959 views

Review

Published on 02 Aug 2017

Pseudotyped Lentiviral Vectors for Retrograde Gene Delivery into Target Brain Regions

Kenta Kobayashi
Ken-ichi Inoue
Soshi Tanabe
Shigeki Kato
Masahiko Takada
Kazuto Kobayashi

Frontiers in Neuroanatomy

doi 10.3389/fnana.2017.00065

11,231 views
34 citations

Mini Review

Published on 21 Jun 2016

Recent Advances in Lentiviral Vaccines for HIV-1 Infection

in HIV and AIDS

Thomas D. Norton
Elizabeth A. Miller

Frontiers in Immunology

doi 10.3389/fimmu.2016.00243

9,002 views
20 citations

Original Research

Published on 13 Jul 2023

CRISPR library screening to develop HEK293-derived cell lines with improved lentiviral vector titers

in Genome Editing Tools and Mechanisms

Brian J. Iaffaldano
Michael P. Marino
Jakob Reiser

Frontiers in Genome Editing

doi 10.3389/fgeed.2023.1218328

12,765 views
8 citations

Original Research

Published on 29 Apr 2020

Production of Vesicular Stomatitis Virus Glycoprotein-Pseudotyped Lentiviral Vector Is Enhanced by Ezrin Silencing

in Biomaterials

Mai Izumida
Kei Togawa
Hideki Hayashi
Toshifumi Matsuyama
Yoshinao Kubo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00368

8,703 views
6 citations

Original Research

Published on 27 Jul 2021

Assessment of Lentiviral Vector Mediated CFTR Correction in Mice Using an Improved Rapid in vivo Nasal Potential Difference Measurement Protocol

in Respiratory Pharmacology

P. Cmielewski
J. Delhove
M. Donnelley
D. Parsons

Frontiers in Pharmacology

doi 10.3389/fphar.2021.714452

3,660 views
5 citations

Perspective

Published on 29 May 2025

Challenges in lentiviral vector production: retro-transduction of producer cell lines

in Cell and Gene Therapy

Maximilian Klimpel
Christin Obert
Monica Terrao
Parameswari Singh
Haiyan Wei
Chao-Guang Chen
Andreas Gille
Silke Wissing
Holger Laux

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1569298

7,209 views
5 citations

Original Research

Published on 15 Aug 2014

Aging reduces glial uptake and promotes extracellular accumulation of Aβ from a lentiviral vector

in Alzheimer's Disease and Related Dementias

Wenjuan Zhao
Jiguo Zhang
Elizabeth G. Davis
G. William Rebeck

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00210

10,559 views
24 citations

Original Research

Published on 09 Sep 2024

Correction of osteopetrosis in the neonate oc/oc murine model after lentiviral vector gene therapy and non-genotoxic conditioning

in Bone Research

Sara Penna
Alessandra Zecchillo
Martina Di Verniere
Elena Fontana
Valeria Iannello
Eleonora Palagano
Stefano Mantero
Andrea Cappelleri
Elena Rizzoli
Ludovica Santi

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1450349

3,910 views
3 citations

Original Research

Published on 06 Jun 2025

Transduction of γδ T cells with Baboon envelope pseudotyped lentiviral vector encoding chimeric antigen receptors for translational and clinical applications

in Cancer Immunity and Immunotherapy

Lorraine Pinot
Aylin Saßor
Nina Möker
Congcong Zhang
Els Verhoeyen
José Villacorta Hidalgo
Rimas J. Orentas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1548630

10,639 views
8 citations

Original Research

Published on 27 Jun 2023

Asbestos accelerates disease onset in a genetic model of malignant pleural mesothelioma

in Immunotoxicology

Pooyeh Farahmand
Katarina Gyuraszova
Claire Rooney
Ximena L. Raffo-Iraolagoitia
Geeshath Jayasekera
Ann Hedley
Emma Johnson
Tatyana Chernova
Gaurav Malviya
Holly Hall

Frontiers in Toxicology

doi 10.3389/ftox.2023.1200650

5,740 views
5 citations

Articles

Degradation of specific glycosaminoglycans improves transfection efficiency and vector production in transient lentiviral vector manufacturing processes

Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations

Long-Term Labeling of Hippocampal Neural Stem Cells by a Lentiviral Vector

Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15II in Murine Model

Integrase Defective Lentiviral Vector as a Vaccine Platform for Delivering Influenza Antigens

Transduction of hematopoietic stem and progenitor cells by an MECP2 lentiviral vector improves Rett syndrome phenotypes

Pseudotyped Lentiviral Vectors for Retrograde Gene Delivery into Target Brain Regions

Recent Advances in Lentiviral Vaccines for HIV-1 Infection

CRISPR library screening to develop HEK293-derived cell lines with improved lentiviral vector titers

Production of Vesicular Stomatitis Virus Glycoprotein-Pseudotyped Lentiviral Vector Is Enhanced by Ezrin Silencing

Assessment of Lentiviral Vector Mediated CFTR Correction in Mice Using an Improved Rapid in vivo Nasal Potential Difference Measurement Protocol

Challenges in lentiviral vector production: retro-transduction of producer cell lines

Aging reduces glial uptake and promotes extracellular accumulation of Aβ from a lentiviral vector

Correction of osteopetrosis in the neonate oc/oc murine model after lentiviral vector gene therapy and non-genotoxic conditioning

Transduction of γδ T cells with Baboon envelope pseudotyped lentiviral vector encoding chimeric antigen receptors for translational and clinical applications

Asbestos accelerates disease onset in a genetic model of malignant pleural mesothelioma