Male Factor | List of Frontiers open access articles

Original Research

Published on 16 May 2023

Novel mutations in PLCZ1 lead to early embryonic arrest as a male factor

in Molecular and Cellular Reproduction

Yunying Lin
Yi Huang
Boyu Li
Ting Zhang
Yichao Niu
Shuanggang Hu
Ying Ding
Guangxin Yao
Zhe Wei
Ning Yao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2023.1193248

5,708 views
15 citations

Original Research

Published on 17 Sep 2025

Comparison of conventional ICSI and rescue ICSI in patients without severe male factor and poor oocyte yield

in Reproduction

Mingzhao Li
Wennan Chen
Xia Xue

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1637404

1,525 views
1 citation

Original Research

Published on 07 Oct 2022

Ovarian stimulation in IVF couples with severe male factor infertility: GnRH antagonist versus long GnRH agonist

in Reproduction

Mu Lv
Juanjuan Yu
Peiqin Chen
Qimeng Xiao
Liqun Lou
Yifan Luo
Mu Yuan
Yuan Xu
Youji Feng
Mingzhu Bai

Frontiers in Endocrinology

doi 10.3389/fendo.2022.1037220

4,375 views
4 citations

Original Research

Published on 16 May 2023

Human sperm proteome reveals the effect of environmental borne seminal polyaromatic hydrocarbons exposome in etiology of idiopathic male factor infertility

in Molecular and Cellular Pathology

Jasmine Nayak
Soumya Ranjan Jena
Sugandh Kumar
Sujata Kar
Anshuman Dixit
Luna Samanta

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2023.1117155

5,110 views
16 citations

Study Protocol

Published on 22 Jul 2024

The effect of Chinese herbal medicine on male factor infertility: study protocol for a randomized controlled trial

in Reproduction

Qidan Wen
Huanying Xu
Haoxi Zou
Pei Wang
Xiaoyan Xing
Ying Chen
Qiaoling Zhu
Yu Chen
Minhua Tan
Miaomiao Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1418936

34,949 views
2 citations

General Commentary

Published on 21 Nov 2025

Commentary: Comparison of conventional ICSI and rescue ICSI in patients without severe male factor and poor oocyte yield

in Reproduction

Bangbei Wan
Weiying Lu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1719972

529 views

Original Research

Published on 10 Feb 2026

Machine learning–based prediction of IVF/ICSI outcomes in male factor infertility highlighting couple-level BMI

in Obesity

Hu Li
Jie Gao
Yiran Li

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1772106

325 views

Mini Review

Published on 29 Jan 2020

Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update

in Cell Growth and Division

Alaaeldin Saleh
Junaid Kashir
Angelos Thanassoulas
Bared Safieh-Garabedian
F. Anthony Lai
Michail Nomikos

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.00028

26,180 views
67 citations

Review

Published on 05 Oct 2023

High sperm DNA fragmentation: do we have robust evidence to support antioxidants and testicular sperm extraction to improve fertility outcomes? a narrative review

in Reproduction

Massimo Romano
Federico Cirillo
Daria Spadaro
Andrea Busnelli
Stefano Castellano
Elena Albani
Paolo Emanuele Levi-Setti

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1150951

16,031 views
14 citations

Original Research

Published on 02 Oct 2023

Exploration of the correlation of serum polychlorinated biphenyl levels with luteal phase hormonal parameters and infertility in women with or without polycystic ovary syndrome

in Reproduction

Alexandra E. Butler
Edwina Brennan
Daniel S. Drage
Thozhukat Sathyapalan
Stephen L. Atkin

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1270949

3,258 views
3 citations

Mini Review

Published on 05 Jan 2022

The Impact of Oxidative Stress in Male Infertility

in Molecular Diagnostics and Therapeutics

Amanda Mannucci
Flavia Rita Argento
Eleonora Fini
Maria Elisabetta Coccia
Niccolò Taddei
Matteo Becatti
Claudia Fiorillo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.799294

26,385 views
163 citations

Perspective

Published on 04 Mar 2022

Fertilization, Oocyte Activation, Calcium Release and Epigenetic Remodelling: Lessons From Cancer Models

in Molecular and Cellular Reproduction

Areez Shafqat
Junaid Kashir
Sulaiman Alsalameh
Khaled Alkattan
Ahmed Yaqinuddin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.781953

8,922 views
16 citations

Brief Research Report

Published on 11 Oct 2021

Telomere Signaling and Maintenance Pathways in Spermatozoa of Infertile Men Treated With Antioxidants: An in silico Approach Using Bioinformatic Analysis

in Signaling

Manesh Kumar Panner Selvam
Saradha Baskaran
Suresh C. Sikka

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.768510

3,995 views
8 citations

Original Research

Published on 27 Aug 2025

Mechanisms of c-Fos regulation of mTOR signaling via ERα/β in abnormal lipid metabolism of granulosa cells in PCOS

in Reproduction

Xinyi Chen
Xiaoxue Shen
Shanyue Guan
Yan Liu
Ning Song
Wenyan Song
Haixia Jin

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1587595

2,565 views
1 citation

Brief Research Report

Published on 23 May 2025

Distinct germ-line genetic mutation patterns correlate with reproductive outcomes in ICSI patients: a pilot study

in Human and Medical Genomics

Ting Jiang
Yan Wang
Wandai Wu
Qianru Yang
Sixian Wu
Xueguang Zhang
Wenming Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1610943

2,523 views

Original Research

Published on 28 Feb 2022

Molecular Signatures Correlated With Poor IVF Outcomes: Insights From the mRNA and lncRNA Expression of Endometriotic Granulosa Cells

in Reproduction

Libing Shi
Xianjiang Wei
Bingbing Wu
Chunhui Yuan
Chao Li
Yongdong Dai
Jianmin Chen
Feng Zhou
Xiang Lin
Songying Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2022.825934

5,909 views
12 citations

Articles

Novel mutations in PLCZ1 lead to early embryonic arrest as a male factor

Comparison of conventional ICSI and rescue ICSI in patients without severe male factor and poor oocyte yield

Ovarian stimulation in IVF couples with severe male factor infertility: GnRH antagonist versus long GnRH agonist

Human sperm proteome reveals the effect of environmental borne seminal polyaromatic hydrocarbons exposome in etiology of idiopathic male factor infertility

The effect of Chinese herbal medicine on male factor infertility: study protocol for a randomized controlled trial

Commentary: Comparison of conventional ICSI and rescue ICSI in patients without severe male factor and poor oocyte yield

Machine learning–based prediction of IVF/ICSI outcomes in male factor infertility highlighting couple-level BMI

Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update

High sperm DNA fragmentation: do we have robust evidence to support antioxidants and testicular sperm extraction to improve fertility outcomes? a narrative review

Exploration of the correlation of serum polychlorinated biphenyl levels with luteal phase hormonal parameters and infertility in women with or without polycystic ovary syndrome

The Impact of Oxidative Stress in Male Infertility

Fertilization, Oocyte Activation, Calcium Release and Epigenetic Remodelling: Lessons From Cancer Models

Telomere Signaling and Maintenance Pathways in Spermatozoa of Infertile Men Treated With Antioxidants: An in silico Approach Using Bioinformatic Analysis

Mechanisms of c-Fos regulation of mTOR signaling via ERα/β in abnormal lipid metabolism of granulosa cells in PCOS

Distinct germ-line genetic mutation patterns correlate with reproductive outcomes in ICSI patients: a pilot study

Molecular Signatures Correlated With Poor IVF Outcomes: Insights From the mRNA and lncRNA Expression of Endometriotic Granulosa Cells