Medical Innovation | List of Frontiers open access articles

Original Research

Published on 02 Oct 2025

Early pathological changes in the liver and kidney of non-obese diabetic (NOD) mice: involvement of iron accumulation and ferroptosis

in Diabetes: Molecular Mechanisms

Ana Stancic
Milica Markelic
Nevena Savic
Ksenija Velickovic
Vesna Martinovic
Andjelija Gudelj
Danica Velickovic
Ilijana Grigorov
Vesna Otasevic

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1673012

Original Research

Published on 02 Oct 2025

The relationship between thyroid hormones sensitivity and hyperhomocysteinemia: a cross-sectional study based on Chinese health check-up population

in Thyroid Endocrinology

Rui Gong
Jiao Xie
Lixia Yu
Yan Ling
Shi Wang
Rui Min
Sanping Xu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1634589

395 views

Mini Review

Published on 02 Oct 2025

Ovarian aging: pathophysiology and recent developments in maintaining ovarian reserve

in Endocrinology of Aging

Mana Hirano
Takako Onodera
Kazuki Takasaki
Yuko Takahashi
Takayuki Ichinose
Haruka Nishida
Haruko Hiraike
Kazunori Nagasaka

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1619516

818 views

Original Research

Published on 02 Oct 2025

Economic footprint assessment of storm surge disasters in China based on disastrously-extended input-output analysis

in Marine Affairs and Policy

Rui Han
Kedong Yin
Xin Dai
Huishang Li
Shiwei Zhou

Frontiers in Marine Science

doi 10.3389/fmars.2025.1673928

351 views

Original Research

Published on 02 Oct 2025

Calendar time trends in synchronous metastatic urinary bladder cancer before and after the introduction of immune checkpoint inhibitors: a nation-wide population-based cohort study

in Genitourinary Oncology

Karin Söderkvist
Christel Häggström
Oskar Hagberg
Firas Aljabery
Truls Gårdmark
Lars Holmberg
Abolfazl Hosseini
Tomas Jerlström
Henrik Kjölhede
Per-Uno Malmström

Frontiers in Oncology

doi 10.3389/fonc.2025.1680916

194 views

Original Research

Published on 02 Oct 2025

Changes in retinal vessel oxygen saturation using automated retinal oximetry in patients with significant carotid stenosis

in Neuro-Ophthalmology

Petr Polidar
Barbora Pašková
Marta Karhanová
Martin Šín
Tomáš Mudroch
Tomáš Dorňák
Zuzana Schreiberová
Petra Divišová
Tomáš Veverka
David Franc

Frontiers in Neurology

doi 10.3389/fneur.2025.1600749

1,088 views

Clinical Trial

Published on 02 Oct 2025

Aerobic exercise improves clinical symptoms in people with Parkinson’s disease and its potential mechanism

in Movement Disorders

Quanqing Wei
Hui Wang
Yuning Liu
Fengli Wang
Xin Wu
Chuanying Xu
Guiyun Cui
Jie Xiang

Frontiers in Neurology

doi 10.3389/fneur.2025.1658162

236 views

Systematic Review

Published on 02 Oct 2025

The role of interventional radiology in pain management for multiple myeloma: a literature review

in Blood Cancer

Atlee Witt
Saumya Aujla
Meaghan Dendy Case

Frontiers in Hematology

doi 10.3389/frhem.2025.1649720

399 views

Systematic Review

Published on 02 Oct 2025

Effects of probiotic supplementation on islet β-cell function in subjects with glucose metabolism disorders: a meta-analysis

in Nutrition and Metabolism

Mengyue Xiang
Xingkang Sa
Zemin Tuo
Jiwen Bian
Peng Wang
Xinming Zhang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1668470

329 views

Review

Published on 02 Oct 2025

Mediterranean diet in preeclampsia prevention: mechanisms of action and clinical evidence

in Clinical Nutrition

Dimitris Baroutis
Alexander Papadopoulos
Aikaterini-Gavriela Giannakaki
Eleni Katsianou
Panagiotis Antsaklis
Marianna Theodora
George Daskalakis
Thomas Kotsis

Frontiers in Nutrition

doi 10.3389/fnut.2025.1626022

364 views

Original Research

Published on 02 Oct 2025

Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage polarization

in Inflammation

Maolin Chu
Suna Jiang
Jiawei Xue
Wenjing Li
Guanhua Jing
Hongying Li
Juan Zhang
Wanhai Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658989

312 views

Original Research

Published on 02 Oct 2025

Global burden of four cardiovascular diseases attributable to low fruits and vegetables intake, 1990–2021, with a forecast to 2044

in Nutritional Epidemiology

Xin He
JiaXin Huang
Hua Cao
Zhangbo Cheng

Frontiers in Nutrition

doi 10.3389/fnut.2025.1655651

629 views

Study Protocol

Published on 02 Oct 2025

Sustainable innovation with a method based on peripheral mononuclear cells to screen, monitor and stratify the population at risk of osteoporosis and fractures – a multicenter cross-sectional trial protocol

in Bone Research

Francesca Salamanna
Silvia Brogini
Alberto Di Martino
Nicola Baldini
Agostino Gaudio
Pietro Castellino
Deyanira Contartese
Chiara Di Censo
Gianluca Giavaresi
Cesare Faldini

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1647800

Case Report

Published on 02 Oct 2025

Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

in Pediatric Oncology

Yuxing Sun
Jun Zhou
Jiaojiao Zhu
Ming Li
Shiwu Yang
Songtao Bin
Li Tan

Frontiers in Oncology

doi 10.3389/fonc.2025.1640216

713 views

Original Research

Published on 02 Oct 2025

Acute beetroot juice supplementation enhances judo-specific performance, explosive power, and muscular strength in recreational adolescent judokas: a randomized crossover trial

in Sport and Exercise Nutrition

Abdullah Demirli
Eda Gökçelik
Abdorreza Eghbal Moghanlou
Muhammed Hüseyin Ocak
Merve Terzi
Emre Yamaner
Müjde Atıcı
Ömer Akyüz
Ali Burak Toy

Frontiers in Nutrition

doi 10.3389/fnut.2025.1669799

665 views

Systematic Review

Published on 02 Oct 2025

Mapping the relationship between obesity and endometrial cancer: current research hotspots and future trends (2003-2024)

in Gynecological Oncology

Lei Liang
Chuangxiu Song
Bo Yang
Chun Chang
Shichao Chen
Li Sun

Frontiers in Oncology

doi 10.3389/fonc.2025.1567022

231 views

Articles

Early pathological changes in the liver and kidney of non-obese diabetic (NOD) mice: involvement of iron accumulation and ferroptosis

The relationship between thyroid hormones sensitivity and hyperhomocysteinemia: a cross-sectional study based on Chinese health check-up population

Ovarian aging: pathophysiology and recent developments in maintaining ovarian reserve

Economic footprint assessment of storm surge disasters in China based on disastrously-extended input-output analysis

Calendar time trends in synchronous metastatic urinary bladder cancer before and after the introduction of immune checkpoint inhibitors: a nation-wide population-based cohort study

Changes in retinal vessel oxygen saturation using automated retinal oximetry in patients with significant carotid stenosis

Aerobic exercise improves clinical symptoms in people with Parkinson’s disease and its potential mechanism

The role of interventional radiology in pain management for multiple myeloma: a literature review

Effects of probiotic supplementation on islet β-cell function in subjects with glucose metabolism disorders: a meta-analysis

Mediterranean diet in preeclampsia prevention: mechanisms of action and clinical evidence

Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage polarization

Global burden of four cardiovascular diseases attributable to low fruits and vegetables intake, 1990–2021, with a forecast to 2044

Sustainable innovation with a method based on peripheral mononuclear cells to screen, monitor and stratify the population at risk of osteoporosis and fractures – a multicenter cross-sectional trial protocol

Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

Acute beetroot juice supplementation enhances judo-specific performance, explosive power, and muscular strength in recreational adolescent judokas: a randomized crossover trial

Mapping the relationship between obesity and endometrial cancer: current research hotspots and future trends (2003-2024)