Metreleptin | List of Frontiers open access articles

Case Report

Published on 18 Nov 2025

Case Report: Metreleptin treatment enables successful pregnancy in a female with congenital generalized lipodystrophy

in Clinical Diabetes

Maria Somali
Emmanouil Korakas
Eirini Pizirtzidou
Zoe A. Efstathiadou
Michail Sapranidis
Zadalla Mouslech

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1715799

1,687 views

Case Report

Published on 31 May 2021

Case Report: Metreleptin and SGLT2 Inhibitor Combination Therapy Is Effective for Acquired Incomplete Lipodystrophy

in Obesity

Ayako Nagayama
Kenji Ashida
Miki Watanabe
Kanoko Moritaka
Aya Sonezaki
Yoichiro Kitajima
Hirokazu Takahashi
Satoko Yoshinobu
Shimpei Iwata
Junichi Yasuda

Frontiers in Endocrinology

doi 10.3389/fendo.2021.690996

7,411 views
8 citations

Case Report

Published on 13 May 2026

Case Report: Twenty years of metreleptin therapy in congenital generalized lipodystrophy type 1: the longest reported follow-up to date

in Clinical Diabetes

Elise Van der Borght
Bart Van der Schueren
Roman Vangoitsenhoven
David Cassiman
Baris Akinci
Rebecca J. Brown
Elif A. Oral
Ann Mertens
Pieter-Jan Martens

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1815903

281 views

Case Report

Published on 08 Jun 2021

Case Report: Metreleptin Treatment in a Patient With a Novel Mutation for Familial Partial Lipodystrophy Type 3, Presenting With Uncontrolled Diabetes and Insulin Resistance

in Obesity

Vaia Lambadiari
Aikaterini Kountouri
Eirini Maratou
Stavros Liatis
George D. Dimitriadis
Fredrik Karpe

Frontiers in Endocrinology

doi 10.3389/fendo.2021.684182

6,710 views
16 citations

Case Report

Published on 09 Nov 2023

Case report: Rapid improvements of anorexia nervosa and probable myalgic encephalomyelitis/chronic fatigue syndrome upon metreleptin treatment during two dosing episodes

in Adolescent and Young Adult Psychiatry

Johannes Hebebrand
Jochen Antel
Linda von Piechowski
Cordula Kiewert
Burkhard Stüve
Gertraud Gradl-Dietsch

Frontiers in Psychiatry

doi 10.3389/fpsyt.2023.1267495

6,472 views
5 citations

Review

Published on 17 May 2019

Clinical Trials Required to Assess Potential Benefits and Side Effects of Treatment of Patients With Anorexia Nervosa With Recombinant Human Leptin

in Eating Behavior

Johannes Hebebrand
Gabriella Milos
Martin Wabitsch
Martin Teufel
Dagmar Führer
Judith Bühlmeier
Lars Libuda
Christine Ludwig
Jochen Antel

Frontiers in Psychology

doi 10.3389/fpsyg.2019.00769

15,637 views
64 citations

Mini Review

Published on 04 May 2022

Treatment Options for Lipodystrophy in Children

in Pediatric Endocrinology

Francesca Mainieri
Veronica Maria Tagi
Francesco Chiarelli

Frontiers in Endocrinology

doi 10.3389/fendo.2022.879979

8,452 views
9 citations

Original Research

Published on 21 May 2025

A real-world pharmacovigilance assessment and literature review of lymphoma development in lipodystrophy

in Cancer Endocrinology

Rebecca J. Brown
David Araujo-Vilar
Kelly J. Walkovich
Alexandru Barbarosie
David A. Magee
Baris Akinci
Elif A. Oral

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1582715

5,145 views
1 citation

Articles

Case Report: Metreleptin treatment enables successful pregnancy in a female with congenital generalized lipodystrophy

Case Report: Metreleptin and SGLT2 Inhibitor Combination Therapy Is Effective for Acquired Incomplete Lipodystrophy

Case Report: Twenty years of metreleptin therapy in congenital generalized lipodystrophy type 1: the longest reported follow-up to date

Case Report: Metreleptin Treatment in a Patient With a Novel Mutation for Familial Partial Lipodystrophy Type 3, Presenting With Uncontrolled Diabetes and Insulin Resistance

Case report: Rapid improvements of anorexia nervosa and probable myalgic encephalomyelitis/chronic fatigue syndrome upon metreleptin treatment during two dosing episodes

Clinical Trials Required to Assess Potential Benefits and Side Effects of Treatment of Patients With Anorexia Nervosa With Recombinant Human Leptin

Treatment Options for Lipodystrophy in Children

A real-world pharmacovigilance assessment and literature review of lymphoma development in lipodystrophy