Mixed Methods Research | List of Frontiers open access articles

Original Research

Published on 05 Nov 2025

Pex1 loss-of-function in zebrafish is viable and recapitulates hallmarks of Zellweger spectrum disorders

in Molecular Signalling and Pathways

Ursula Heins-Marroquin
Zlatan Hodzic
Beatriz Soares Carneiro da Silva
Agnes Hendriks
Floriane Gavotto
Marc O. Warmoes
Lisa Schlicker
Samy Omri
Christian Jäger
Enrico Glaab

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1634536

264 views

Case Report

Published on 05 Nov 2025

Case Report: identification of a novel 9.159-kb deletion in a Chinese α-thalassemia family using single molecule real-time technology sequencing

in Genetics of Common and Rare Diseases

Shulin Wu
Zonghui Feng
Fuxiang Jiang
Min Zhao
Peng Jiang
Gang Xiao
Xian Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1669814

174 views

Original Research

Published on 05 Nov 2025

The impact of social support on the quality of sports participation among individuals with disabilities: the chain mediating effects of psychological capital and self-esteem

in Movement Science

Jiahui Peng
Li Cao
Feixuan Li
Deqiao Zhou

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1662636

326 views

Original Research

Published on 05 Nov 2025

The mechanism of digital feedback on health information anxiety among older adults: information processing self-efficacy as a mediating variable

in Aging and Public Health

Yang Zhu
Xin Wang
Xiao Zhang
Yan Li
Yepeng Chen

Frontiers in Public Health

doi 10.3389/fpubh.2025.1676970

376 views

Original Research

Published on 05 Nov 2025

Alterations of lipoprotein subfractions in GH-deficient adults

in Pituitary Endocrinology

Balázs Ratku
Hajnalka Lőrincz
Sára Csiha
Lajos Bíró
Annamária Erdei
Eszter Berta
Dóra Ujvárosy
Miklós Bodor
Endre V. Nagy
Zoltán Szabó

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1696426

298 views

Review

Published on 05 Nov 2025

Overcoming resistance to immune checkpoint inhibitor in non-small cell lung cancer: the promise of combination therapy

in Cancer Immunity and Immunotherapy

Xuebing Shi
Wenxia Deng
Yunlei Pan
Yingchun Chen
Yinke Wang
Jing Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691980

454 views

Review

Published on 05 Nov 2025

Establishing a skills laboratory in a Brazilian University Hospital: introducing clinical simulation for pediatric emergencies

in Healthcare Professions Education

Fernando Belluomini
Andrea de Melo Alexandre Fraga
Fernando Augusto Lima Marson
Lucas Silva Mello
Patrícia Teixeira Costa
Paulo Cesar Massucatto Colbachini
Angélica Maria Bicudo

Frontiers in Medicine

doi 10.3389/fmed.2025.1579250

Original Research

Published on 05 Nov 2025

Exploring the nexus between climate finance, rural–urban disparities, and rural brain drain in Somalia: the mediating role of climate resilience

in Migration and Society

Mohamed Ibrahim Nor

Frontiers in Sociology

doi 10.3389/fsoc.2025.1702333

247 views

Brief Research Report

Published on 05 Nov 2025

Associations between diet quality, food insecurity, physical activity, social connectedness and depressive symptomology in Australian university students: a cross-sectional study

in Nutrition, Psychology and Brain Health

Simone O’Neill
Michelle Minehan
Catherine R. Knight-Agarwal
Vivienne Lewis
David B. Pyne

Frontiers in Nutrition

doi 10.3389/fnut.2025.1692643

352 views

Original Research

Published on 05 Nov 2025

Fram strait—possible key to saving arctic ice

in Climate Adaptation

Detelina Ivanova
Subarna Bhattacharyya
Velimir Mlaker
Anthony Strawa
Leslie Field
Tim Player
Alexander Sholtz

Frontiers in Climate

doi 10.3389/fclim.2025.1569470

389 views

Review

Published on 05 Nov 2025

Legal frameworks and practical challenges: a review of the enduring failure to prevent family separations in armed conflicts

in Pediatric Psychology

Neil Boothby

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1629843

182 views

Original Research

Published on 05 Nov 2025

Reflections on brand image: the influence of donor ideal and perceived charity brand congruence on charitable giving

in Advertising and Marketing Communication

Elizabeth Crisp Crawford
Jeremy Jay Jackson

Frontiers in Communication

doi 10.3389/fcomm.2025.1682863

367 views

Policy and Practice Reviews

Published on 05 Nov 2025

Driving the future of value-based healthcare in the Gulf Cooperation Council: a roadmap for achieving sustainable access to specialty pharmaceuticals

in Public Health Policy

Anas Hamad
Ahmed Al-Jedai
Rita Ojeil
Abdulrazaq Sheikh Al-Jazairi
Adel AlAssy
Yazed S. AlRuthia
Waiel Al Naeem
Hajer Almudaiheem
Mouza Alsaadi
Nada Alagil

Frontiers in Public Health

doi 10.3389/fpubh.2025.1667846

453 views

Clinical Trial

Published on 05 Nov 2025

Combination of remazolam and alfentanil on hemodynamics, postoperative cognitive function, and adverse cardiovascular events in elderly patients undergoing laparoscopic cholecystectomy: a randomized controlled trial

in Translational Pharmacology

Chaolei Liu
Jin Li
Junna He
Jingjing Zhang
Lijun Bo
Jiaojiao Yang
Yuan Ma
Jianzhang Qin
Yanjie Yang
Zhangnan Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1653593

167 views

Original Research

Published on 05 Nov 2025

Correlation between Epstein–Barr virus and anti-cytomegalovirus/-herpes simplex virus/-Toxoplasma gondii antibodies in Chongqing, China: a cross-sectional observational study

in Infectious Diseases: Pathogenesis and Therapy

Youyu Zhang
Shupeng Song
Yilin Wu
Beining Ding
Xuenuo Chen
Qian Li
Yuxia Du
Huiling Liu
Yongguo Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1661969

340 views

Review

Published on 05 Nov 2025

Severe alcohol use and COVID-19: implications for physical and mental health

in Addictive Disorders

Javier Calleja-Conde
Víctor Echeverry-Alzate
Sara Sánchez-Diez
Elena Giné
Kora-Mareen Bühler

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1640207

Articles

Pex1 loss-of-function in zebrafish is viable and recapitulates hallmarks of Zellweger spectrum disorders

Case Report: identification of a novel 9.159-kb deletion in a Chinese α-thalassemia family using single molecule real-time technology sequencing

The impact of social support on the quality of sports participation among individuals with disabilities: the chain mediating effects of psychological capital and self-esteem

The mechanism of digital feedback on health information anxiety among older adults: information processing self-efficacy as a mediating variable

Alterations of lipoprotein subfractions in GH-deficient adults

Overcoming resistance to immune checkpoint inhibitor in non-small cell lung cancer: the promise of combination therapy

Establishing a skills laboratory in a Brazilian University Hospital: introducing clinical simulation for pediatric emergencies

Exploring the nexus between climate finance, rural–urban disparities, and rural brain drain in Somalia: the mediating role of climate resilience

Associations between diet quality, food insecurity, physical activity, social connectedness and depressive symptomology in Australian university students: a cross-sectional study

Fram strait—possible key to saving arctic ice

Legal frameworks and practical challenges: a review of the enduring failure to prevent family separations in armed conflicts

Reflections on brand image: the influence of donor ideal and perceived charity brand congruence on charitable giving

Driving the future of value-based healthcare in the Gulf Cooperation Council: a roadmap for achieving sustainable access to specialty pharmaceuticals

Combination of remazolam and alfentanil on hemodynamics, postoperative cognitive function, and adverse cardiovascular events in elderly patients undergoing laparoscopic cholecystectomy: a randomized controlled trial

Correlation between Epstein–Barr virus and anti-cytomegalovirus/-herpes simplex virus/-Toxoplasma gondii antibodies in Chongqing, China: a cross-sectional observational study

Severe alcohol use and COVID-19: implications for physical and mental health