Normothermic Perfusion | List of Frontiers open access articles

Original Research

Published on 04 Apr 2024

Extending heart preservation to 24 h with normothermic perfusion

in Heart Failure and Transplantation

Brianna L. Spencer
Spencer K. Wilhelm
Christopher Stephan
Kristopher A. Urrea
Daniela Pelaez Palacio
Robert H. Bartlett
Daniel H. Drake
Alvaro Rojas-Pena

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1325169

7,708 views
8 citations

Brief Research Report

Published on 12 Jan 2024

Ex vivo normothermic preservation of a kidney graft from uncontrolled donation after circulatory death over 73 hours

in Tissue Engineering and Regenerative Medicine

Enrique Montagud-Marrahi
Yosu Luque
Ruben Rabadan Ros
Tarek Ajami
Elena Cuadrado-Payan
Hector Estrella
Andres Arancibia
Gerard Sánchez-Etayo
Marc Bohils
Ramsés Marrero

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2023.1330043

4,085 views
9 citations

Original Research

Published on 03 Oct 2025

Ex vivo rat heart normothermic perfusion with intermittent low flow and triiodothyronine

in Heart Failure and Transplantation

Iordanis Mourouzis
Dimitris Anagnostopoulos
Vassiliki Brozou
Dimitris Kounatidis
Dimitris Giannoulis
Athanasios Lourbopoulos
Theodosios Saranteas
Constantinos Pantos

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1607594

1,388 views

Original Research

Published on 26 Jul 2022

Pan-caspase inhibition during normothermic machine perfusion of discarded livers mitigates ex situ innate immune responses

in Alloimmunity and Transplantation

Siavash Raigani
John Santiago
Anders Ohman
Megan Heaney
Sofia Baptista
Taylor M. Coe
Reinier J. de Vries
Ivy Rosales
Angela Shih
James F. Markmann

Frontiers in Immunology

doi 10.3389/fimmu.2022.940094

5,496 views
21 citations

Original Research

Published on 17 Feb 2021

Ex situ Normothermic Split Liver Machine Perfusion: Protocol for Robust Comparative Controls in Liver Function Assessment Suitable for Evaluation of Novel Therapeutic Interventions in the Pre-clinical Setting

in Visceral Surgery

Joseph A. Attard
Daniel-Clement Osei-Bordom
Yuri Boteon
Lorraine Wallace
Vincenzo Ronca
Gary Reynolds
M. T. P. R. Perera
Ye Htun Oo
Hynek Mergental
Darius F. Mirza

Frontiers in Surgery

doi 10.3389/fsurg.2021.627332

5,598 views
15 citations

Mini Review

Published on 21 Oct 2022

Breaking the limits of experimental pancreas transplantation: Working toward the clinical ideal graft

in Organ and Tissue Preservation

Joana Ferrer-Fàbrega
Emma Folch-Puy
Andrea Llaves-López
Rocío García-Pérez
Josep Fuster

Frontiers in Transplantation

doi 10.3389/frtra.2022.1035480

3,367 views
5 citations

Review

Published on 24 Apr 2025

Regulated cell death and DAMPs as biomarkers and therapeutic targets in normothermic perfusion of transplant organs. Part 2: implementation strategies

in Organ and Tissue Preservation

Walter G. Land
Andreas Linkermann

Frontiers in Transplantation

doi 10.3389/frtra.2025.1575703

4,962 views

Case Report

Published on 11 Aug 2023

Case report: Heart retransplant from a donor after circulatory death and extended transport period with normothermic perfusion

in Heart Failure and Transplantation

Patpilai Kasinpila
Chawannuch Ruaengsri
Tiffany Koyano
Yasuhiro Shudo

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2023.1212886

2,041 views
4 citations

Review

Published on 09 Feb 2026

Machine perfusion for liver transplantation: opportunities and challenges for the next generation of transplant surgeons

in Abdominal Transplantation

Cody L. Mullens
Kumaran Shanmugarajah
Glenn K. Wakam

Frontiers in Transplantation

doi 10.3389/frtra.2026.1736191

323 views

Review

Published on 24 Apr 2025

Regulated cell death and DAMPs as biomarkers and therapeutic targets in normothermic perfusion of transplant organs. Part 1: their emergence from injuries to the donor organ

in Organ and Tissue Preservation

Walter G. Land
Andreas Linkermann

Frontiers in Transplantation

doi 10.3389/frtra.2025.1571516

5,437 views
2 citations

Original Research

Published on 28 Feb 2023

Real-time assessment of kidney allografts during HOPE using flavin mononucleotide (FMN) — a preclinical study

in Organ and Tissue Preservation

Richard X. Sousa Da Silva
Tom Darius
Leandro Mancina
Janina Eden
Kendra Wernlé
Ahmed S. Ghoneima
Adam D. Barlow
Pierre-Alain Clavien
Philipp Dutkowski
Philipp Kron

Frontiers in Transplantation

doi 10.3389/frtra.2023.1132673

4,298 views
13 citations

Original Research

Published on 22 Jun 2022

The Immunological Effect of Oxygen Carriers on Normothermic Ex Vivo Liver Perfusion

in Alloimmunity and Transplantation

Heather Jennings
Kristin N. Carlson
Chris Little
Joshua C. Verhagen
Jeevan Nagendran
Yongjun Liu
Bret Verhoven
Weifeng Zeng
Stacey McMorrow
Peter Chlebeck

Frontiers in Immunology

doi 10.3389/fimmu.2022.833243

4,965 views
5 citations

Original Research

Published on 22 Sep 2023

Composition of ex vivo perfusion solutions and kinetics define differential cytokine/chemokine secretion in a porcine cardiac arrest model of lung preservation

in Heart Failure and Transplantation

Lena Radomsky
Achim Koch
Carolin Olbertz
Yongjie Liu
Kerstin Beushausen
Jana Keil
Ursula Rauen
Christine S. Falk
Jenny F. Kühne
Markus Kamler

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2023.1245618

4,114 views
2 citations

Articles

Extending heart preservation to 24 h with normothermic perfusion

Ex vivo normothermic preservation of a kidney graft from uncontrolled donation after circulatory death over 73 hours

Ex vivo rat heart normothermic perfusion with intermittent low flow and triiodothyronine

Pan-caspase inhibition during normothermic machine perfusion of discarded livers mitigates ex situ innate immune responses

Ex situ Normothermic Split Liver Machine Perfusion: Protocol for Robust Comparative Controls in Liver Function Assessment Suitable for Evaluation of Novel Therapeutic Interventions in the Pre-clinical Setting

Breaking the limits of experimental pancreas transplantation: Working toward the clinical ideal graft

Regulated cell death and DAMPs as biomarkers and therapeutic targets in normothermic perfusion of transplant organs. Part 2: implementation strategies

Case report: Heart retransplant from a donor after circulatory death and extended transport period with normothermic perfusion

Machine perfusion for liver transplantation: opportunities and challenges for the next generation of transplant surgeons

Regulated cell death and DAMPs as biomarkers and therapeutic targets in normothermic perfusion of transplant organs. Part 1: their emergence from injuries to the donor organ

Real-time assessment of kidney allografts during HOPE using flavin mononucleotide (FMN) — a preclinical study

The Immunological Effect of Oxygen Carriers on Normothermic Ex Vivo Liver Perfusion

Composition of ex vivo perfusion solutions and kinetics define differential cytokine/chemokine secretion in a porcine cardiac arrest model of lung preservation