Optic Disk | List of Frontiers open access articles

Original Research

Accepted on 12 Nov 2025

Association of Serum miR-99a level and Metabolic dysfunction-associated steatotic liver disease, Serum mTOR levels in Patients with Type 2 Diabetes Mellitus

in Diabetes: Molecular Mechanisms

Yangyang Zhang
Yuqiong Zuo
Qian Chen
Yaqiang Cui
Yanxia Bao
Panpan Jiang
Jing Liu
Jinxing Quan
Juxiang Liu

Frontiers in Endocrinology

109 views

Original Research

Accepted on 12 Nov 2025

Integrating Traditional Omics and AI-Driven Approaches for Discovery and Validation of Novel MicroRNA Biomarkers and Therapeutic Targets in Thyroid Cancer

in Experimental Pharmacology and Drug Discovery

Yi Wan
Dan Xie
Min Zhang
Shiyu Yang
Zhantian Zhang
Xiaomin Fu
Meiling Wang
Yongfu Zhao

Frontiers in Pharmacology

111 views

Systematic Review

Accepted on 12 Nov 2025

Effectiveness of drug-loaded polyethylene glycol-poly lactic acid-co-glycolic acid nanoparticles in the treatment of breast cancer on in vitro studies: a systematic review

in Experimental Pharmacology and Drug Discovery

Cristian Sandoval
Isabella Cárcamo
Paula Lagos
Anaís Muñoz
Francisco Zavala
Valentina Colil
FRANCISCA MARION VILLAGRAN SILVA
Edgar Vásquez-Carrasco
Jordan Hernandez Martinez
Pablo Valdés-Badilla

Frontiers in Pharmacology

121 views

Original Research

Accepted on 12 Nov 2025

Efficacy of sulfonamides targeting malic enzyme in an animal model of Chagas disease

in Experimental Pharmacology and Drug Discovery

Thaís Cristina Ferreira dos Santos
Ramon Borges da Silva
Irene Layane de Souza
Fabrício Fredo Naciuk
Letícia Marchese
Amanda Gonçalves Eufrásio
Angel Eduardo Lobo-Rojas
Renan Marcel Giampauli
Valéria Barbosa de Souza
André Almeida Schenka

Frontiers in Pharmacology

166 views

Original Research

Accepted on 12 Nov 2025

Development and external validation of a nomogram for predicting the risk of developing esophageal cancer based on a questionnaire: a multicenter case-control study

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Zhang Yaling
Tao Sun
Xiaoqi Chen
Dongdong Li
Feifan Feng
Li-han Zhang
Xiaoyu Tang
Jian-Ping Liu
Yuling Zheng

Frontiers in Oncology

Original Research

Accepted on 12 Nov 2025

Survey of Evidence-Based Nursing Practice Readiness for Scoliosis-Specific Rehabilitation Exercise in Orthopedic Nurses

in Healthcare Professions Education

Binglin Li
Ruiman Xu
Shina Cheng
Mingkui Shen
Meng Li
Huawei Li

Frontiers in Medicine

120 views

Original Research

Accepted on 12 Nov 2025

Delivering Emergency Care at the religious mass gathering of India: An amalgamation of technology and spirituality - An institutional experience of managing pilgrims at Mahakumbh Prayagraj

in Disaster and Emergency Medicine

SUYASH SINGH
Kumari Shaloo
Shruti Sinha
Purushottam Kumar
Bhola Nath

Frontiers in Public Health

172 views

Original Research

Accepted on 12 Nov 2025

The Intestinal microbiota of patients with type 2 diabetes is associated with the C-512T polymorphism of the FOXC2 gene

in Clinical Diabetes

Hongjiang Zhou
Lei Liang
xuxiang Zhang
yandan Su
ying Zhao
Xin Nian

Frontiers in Endocrinology

Original Research

Accepted on 12 Nov 2025

cAMP-MFN2 Signaling Suppresses Cochlear Cell Senescence and Age-Related Hearing Loss

in Inflammation

Yu Liu
Jinyuan Cao
Jie Cui
Haitong Chen
Shujing Qin
Qi Li
Zhongwu Su

Frontiers in Immunology

139 views

Case Report

Accepted on 12 Nov 2025

Chlorine gas poisoning by trichloroisocyanuric acid and respiratory failure: A case report of a 49-year-old patient

in Pulmonary Medicine

Yamei Wang
Jun Meng
Xiaowei Tian
Chuihua Sun
Lu Liu
Xiaojuan Sun

Frontiers in Medicine

160 views

Original Research

Accepted on 12 Nov 2025

Mepolizumab treatment alters the functional phenotype of eosinophils in severe eosinophilic asthma

in Inflammation

Pablo Miguéns Suárez
Laura Martelo Vidal
Sara Vázquez Mera
Marina Blanco Aparicio
Uxío Calvo-Álvarez
Coral González Fernández
Mar Mosteiro-Añón
Dolores Corbacho
Tamara Hermida Valverde
Christian Calvo Henríquez

Frontiers in Immunology

111 views

Original Research

Accepted on 12 Nov 2025

Development and validation of a predictive Model for weight loss psychological distress in obese patients:A cross-sectional study

in Public Mental Health

Zhiqiang Cheng
meiling liu
xiaixn li
jiazhen tang
Caihong Huang

Frontiers in Public Health

105 views

Original Research

Accepted on 12 Nov 2025

Pan-Cancer Multi-Omics Characterization of Calcyphosine and Its Revealed 1 Links to the Immune Microenvironment and Regulatory Networks in 2 Endometrial Carcinoma

in Cancer Immunity and Immunotherapy

Xi Chen
Ruiyue Wu
Zijing Wang
Fengfeng Wang
Dan Hu
Xuehan Bi
Xiaolei Liang
Yongxiu Yang

Frontiers in Immunology

Original Research

Accepted on 12 Nov 2025

Universe 2.0: Higgs quantum gravity

in Cosmology

Johannes Böhm-Mäder

Frontiers in Physics

170 views

Case Report

Accepted on 12 Nov 2025

Highly sensitive early-onset Alzheimer's disease: a case report

in Neuropsychology

José Ángel Rubiño
Melania Zapata

Frontiers in Psychology

169 views

Original Research

Accepted on 12 Nov 2025

The influencing factors of postoperative sleep disorders in elderly patients undergoing hip replacement surgery under general anesthesia and the construction and validation of a nomogram prediction model

in Sleep Disorders

Guo Zhou
Jun Chen
Hui Zhang

Frontiers in Neurology

Articles

Association of Serum miR-99a level and Metabolic dysfunction-associated steatotic liver disease, Serum mTOR levels in Patients with Type 2 Diabetes Mellitus

Integrating Traditional Omics and AI-Driven Approaches for Discovery and Validation of Novel MicroRNA Biomarkers and Therapeutic Targets in Thyroid Cancer

Effectiveness of drug-loaded polyethylene glycol-poly lactic acid-co-glycolic acid nanoparticles in the treatment of breast cancer on in vitro studies: a systematic review

Efficacy of sulfonamides targeting malic enzyme in an animal model of Chagas disease

Development and external validation of a nomogram for predicting the risk of developing esophageal cancer based on a questionnaire: a multicenter case-control study

Survey of Evidence-Based Nursing Practice Readiness for Scoliosis-Specific Rehabilitation Exercise in Orthopedic Nurses

Delivering Emergency Care at the religious mass gathering of India: An amalgamation of technology and spirituality - An institutional experience of managing pilgrims at Mahakumbh Prayagraj

The Intestinal microbiota of patients with type 2 diabetes is associated with the C-512T polymorphism of the FOXC2 gene

cAMP-MFN2 Signaling Suppresses Cochlear Cell Senescence and Age-Related Hearing Loss

Chlorine gas poisoning by trichloroisocyanuric acid and respiratory failure: A case report of a 49-year-old patient

Mepolizumab treatment alters the functional phenotype of eosinophils in severe eosinophilic asthma

Development and validation of a predictive Model for weight loss psychological distress in obese patients:A cross-sectional study

Pan-Cancer Multi-Omics Characterization of Calcyphosine and Its Revealed 1 Links to the Immune Microenvironment and Regulatory Networks in 2 Endometrial Carcinoma

Universe 2.0: Higgs quantum gravity

Highly sensitive early-onset Alzheimer's disease: a case report

The influencing factors of postoperative sleep disorders in elderly patients undergoing hip replacement surgery under general anesthesia and the construction and validation of a nomogram prediction model