Pathogenesis Model | List of Frontiers open access articles

Original Research

Accepted on 17 Oct 2025

Immunomodulatory Effect of Betulin and Its Derivatives on IL-6 Expression in Colorectal Cancer Cell Lines and Molecular Docking Insights

in Molecular Diagnostics and Therapeutics

Marcel Madej
Adrianna Halama
Elwira Chrobak
Ewa Bębenek
Joanna Magdalena Gola

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1704804

176 views

Case Report

Accepted on 17 Oct 2025

Case Report: Metachronous pancreatic adenocarcinoma following HER2-positive breast cancer and the implications of non-BRCA germline variants with TP53-mutant disease

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Jing Chen
Hui Chun Zhou
Min Hui Fan
Mei-yao Qin

Frontiers in Oncology

doi 10.3389/fonc.2025.1705199

149 views

Review

Accepted on 17 Oct 2025

Unraveling the complexity of cognitive impairment following high-altitude exposure: from preclinical animal models to human organoids

in Translational Neuroscience

Hong Gong
Yu-Xin Liu
Qing-Lu Xiaoluo
Mei-Feng Gong
Zhi Liu
Sheng-Ru Wu
Zhen-Yang Chen
Tianyao Liu
Jing-Hui Zhao
Lian Wang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1679858

194 views

Original Research

Accepted on 17 Oct 2025

A novel drug that reduces pneumococcal toxicity by targeting pneumolysin (PLY): efficacy of the traditional Chinese medicine Radix Paeoniae Alba

in Pharmacology of Infectious Diseases

Xu Yan
Jing Han
Yonglin Zhou
Liping Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1609457

153 views

Systematic Review

Accepted on 17 Oct 2025

Endocrine Disruption Rewards: Bisphenol-A-Induced Reproductive Toxicity and the Precision Ameliorative Potential of Flavonoids in Preclinical Studies. A Systematic Review and Meta-Analysis

in Developmental and Reproductive Toxicology

Michael Ben Okon
ILEMOBAYO VICTOR FASOGBON
Dominic Terkimbi Swase
Reuben Samson Dangana
Wusa Makena
Vivian Onyinye Ojiakor
Monday Ekom Etukudo
Joan Chebet
Angela Mumbua Musyoka
Sandra Etumah Ifie

Frontiers in Toxicology

doi 10.3389/ftox.2025.1687862

Original Research

Accepted on 17 Oct 2025

"I need to get back to a normal life": using the core DSM-5 Cultural Formulation Interview to explore existential themes shared by adolescents in specialized mental healthcare in Norway

in Psychology for Clinical Settings

Nina Therese Øversveen Svamo
Sigrid Helene Kjørven Haug
Valerie DeMarinis

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1652189

260 views

Systematic Review

Accepted on 17 Oct 2025

Factors Affecting the Effectiveness and Safety of Colistin in Treating Drug-Resistant Gram-Negative Bacterial Infections: A Meta-Analysis

in Pharmacology of Infectious Diseases

Pengfei Li
Shiran Li
Jiao Zhang
Siyu Zeng
Zhimin Li
Jingxian Xie
Yong Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625595

175 views

Perspective

Accepted on 17 Oct 2025

Not Quite a Cure Yet: Unlocking the Unfulfilled Promise of Live Biotherapeutics for Disease Treatment

in Gastrointestinal and Hepatic Pharmacology

Andrea Verdugo-Meza
Han M. Chiang
Emeran A Mayer
Deanna L Gibson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695976

Original Research

Accepted on 17 Oct 2025

Retrospective Analysis of Dietary Fat Quality and Cardiovascular Disease Risk Markers in Middle-Aged Adults

in Nutritional Epidemiology

Yongbo Zhang
Fengling Wang
Bingsen Huang
Miaomiao Li
Changchun Du

Frontiers in Nutrition

doi 10.3389/fnut.2025.1699166

257 views

Original Research

Accepted on 17 Oct 2025

Physical Capacity Modulates Intestinal Barrier Dysfunction in Functional Disorders: Phenotype-Specific Patterns in Fibromyalgia and Irritable Bowel Syndrome

in Gastrointestinal Sciences

Francesco Russo
Antonella Bianco
Laura Prospero
Gaetana Laselva
Marco Grasso
BENEDETTA D'ATTOMA
Nicola Verrelli
Antonia Ignazzi
Isabella Franco
Francesco Goscilo

Frontiers in Physiology

doi 10.3389/fphys.2025.1695163

113 views

Brief Research Report

Accepted on 17 Oct 2025

Predictors of Hematoma Expansion in Intracerebral Hemorrhage Associated with Factor Xa Inhibitors

in Stroke

Yoji Komatsu
Takao Koiso
Tomokazu Sekine
Kazuki Akutagawa
Hiroki Karita
Norie Kikuchi
Tomosato Yamazaki

Frontiers in Neurology

doi 10.3389/fneur.2025.1628563

123 views

Original Research

Accepted on 17 Oct 2025

Transforming Management Education: Blended Learning, International Collaboration, and Pedagogical Innovation – Current Trends and Future Directions

in Digital Learning Innovations

Juergen Bleicher
Emil Velinov
Sunday Adebola

Frontiers in Education

doi 10.3389/feduc.2025.1635715

376 views

Original Research

Accepted on 17 Oct 2025

Caffeine-Augmented Sprint Interval Training Outcomes in Obese Women: An Examination by Inter-Individual Analysis on Physical and Physiological Adaptive Responses

in Sport and Exercise Nutrition

Xinying Zhao
Yang Liu

Frontiers in Nutrition

doi 10.3389/fnut.2025.1655449

204 views

Community Case Study

Accepted on 17 Oct 2025

Partnership for health promotion as a platform to improve public health outcomes in small island developing states: A case study of the Comoros

in Public Health Education and Promotion

Andrea Luciani
Sandrine Abega
Abdoulaye Diarra
Pamela Drameh
Matshidiso Moeti

Frontiers in Public Health

doi 10.3389/fpubh.2025.1666667

155 views

Correction

Accepted on 17 Oct 2025

Diverse economies and food democracy: implications for sustainability from an interdisciplinary perspective

in Social Movements, Institutions and Governance

Andreas Exner
Moya Kneafsey
Andreas Mayer

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1723510

221 views

Original Research

Accepted on 17 Oct 2025

Knowledge-attitude-practice status on ovarian reserve function among women of childbearing age: a latent profile analysis

in Public Health Education and Promotion

Yawen Wang
Fei Sun
Yue Qin
Jue Wang
Aiping Fu
Li Yuan
Xia Lei
Lin Zhou

Frontiers in Public Health

doi 10.3389/fpubh.2025.1660116

165 views

Articles

Immunomodulatory Effect of Betulin and Its Derivatives on IL-6 Expression in Colorectal Cancer Cell Lines and Molecular Docking Insights

Case Report: Metachronous pancreatic adenocarcinoma following HER2-positive breast cancer and the implications of non-BRCA germline variants with TP53-mutant disease

Unraveling the complexity of cognitive impairment following high-altitude exposure: from preclinical animal models to human organoids

A novel drug that reduces pneumococcal toxicity by targeting pneumolysin (PLY): efficacy of the traditional Chinese medicine Radix Paeoniae Alba

Endocrine Disruption Rewards: Bisphenol-A-Induced Reproductive Toxicity and the Precision Ameliorative Potential of Flavonoids in Preclinical Studies. A Systematic Review and Meta-Analysis

"I need to get back to a normal life": using the core DSM-5 Cultural Formulation Interview to explore existential themes shared by adolescents in specialized mental healthcare in Norway

Factors Affecting the Effectiveness and Safety of Colistin in Treating Drug-Resistant Gram-Negative Bacterial Infections: A Meta-Analysis

Not Quite a Cure Yet: Unlocking the Unfulfilled Promise of Live Biotherapeutics for Disease Treatment

Retrospective Analysis of Dietary Fat Quality and Cardiovascular Disease Risk Markers in Middle-Aged Adults

Physical Capacity Modulates Intestinal Barrier Dysfunction in Functional Disorders: Phenotype-Specific Patterns in Fibromyalgia and Irritable Bowel Syndrome

Predictors of Hematoma Expansion in Intracerebral Hemorrhage Associated with Factor Xa Inhibitors

Transforming Management Education: Blended Learning, International Collaboration, and Pedagogical Innovation – Current Trends and Future Directions

Caffeine-Augmented Sprint Interval Training Outcomes in Obese Women: An Examination by Inter-Individual Analysis on Physical and Physiological Adaptive Responses

Partnership for health promotion as a platform to improve public health outcomes in small island developing states: A case study of the Comoros

Diverse economies and food democracy: implications for sustainability from an interdisciplinary perspective

Knowledge-attitude-practice status on ovarian reserve function among women of childbearing age: a latent profile analysis