Periapical Lesion | List of Frontiers open access articles

Systematic Review

Published on 24 Nov 2025

Application and performance of artificial intelligence-based models in the detection, segmentation and classification of periapical lesions: a systematic review

in Periodontics

Ali Alaqla
Sanjeev B. Khanagar
Alzahraa Ibrahim Albelaihi
Oinam Gokulchandra Singh
Abdulmohsen Alfadley

Frontiers in Dental Medicine

doi 10.3389/fdmed.2025.1717343

2,651 views
3 citations

Review

Published on 19 May 2021

Roles of Dental Mesenchymal Stem Cells in the Management of Immature Necrotic Permanent Teeth

in Stem Cell Research

Dixin Cui
Sihan Yu
Xin Zhou
Ying Liu
Lu Gan
Yue Pan
Liwei Zheng
Mian Wan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.666186

11,018 views
18 citations

Mini Review

Published on 05 Sep 2022

Macrophages in periapical lesions: Potential roles and future directions

in Inflammation

Yao Song
Xinying Li
Dingming Huang
Hongjie Song

Frontiers in Immunology

doi 10.3389/fimmu.2022.949102

10,111 views
32 citations

Original Research

Published on 26 Feb 2019

Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis

in Inflammation

Yasir Dilshad Siddiqui
Kazuhiro Omori
Takashi Ito
Keisuke Yamashiro
Shin Nakamura
Kentaro Okamoto
Mitsuaki Ono
Tadashi Yamamoto
Thomas E. Van Dyke
Shogo Takashiba

Frontiers in Immunology

doi 10.3389/fimmu.2019.00307

16,054 views
63 citations

Mini Review

Published on 11 Oct 2018

Platelet-Rich Plasma and Platelet-Rich Fibrin Can Induce Apical Closure More Frequently Than Blood-Clot Revascularization for the Regeneration of Immature Permanent Teeth: A Meta-Analysis of Clinical Efficacy

in Tissue Engineering and Regenerative Medicine

Peter E. Murray

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2018.00139

24,300 views
102 citations

Original Research

Published on 24 Apr 2026

Longitudinal periapical radiographic evaluation of apexification, vital pulpotomy, and revascularization in immature permanent teeth: a retrospective comparative study

in Tissue Engineering and Regenerative Medicine

Xiaona Sun
Kailing Zhu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1792713

569 views

Mini Review

Published on 11 Aug 2022

Revisiting the role of IL-1 signaling in the development of apical periodontitis

in Endodontics

Kento Tazawa
Mariane Maffei Azuma Presse
Hisako Furusho
Philip Stashenko
Hajime Sasaki

Frontiers in Dental Medicine

doi 10.3389/fdmed.2022.985558

5,046 views
22 citations

Original Research

Published on 09 Feb 2024

Sex-specific nociceptor modulation of the apical periodontitis transcriptome

in Cellular Biochemistry

Katherine V. Lillis
Ruta Grinceviciute
Anibal Diogenes

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1338511

3,204 views
3 citations

Original Research

Published on 09 May 2024

Outcomes of root canal treatments with three different sealers for 120 fractured maxillary fourth premolar teeth in small-to medium-sized dogs

in Veterinary Dentistry and Oromaxillofacial Surgery

Daehyun Kwon
Dae Sung Yoo
Seong Soo Kang
Kwangsik Jang
Se Eun Kim

Frontiers in Veterinary Science

doi 10.3389/fvets.2024.1382645

7,045 views
6 citations

Articles

Application and performance of artificial intelligence-based models in the detection, segmentation and classification of periapical lesions: a systematic review

Roles of Dental Mesenchymal Stem Cells in the Management of Immature Necrotic Permanent Teeth

Macrophages in periapical lesions: Potential roles and future directions

Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis

Platelet-Rich Plasma and Platelet-Rich Fibrin Can Induce Apical Closure More Frequently Than Blood-Clot Revascularization for the Regeneration of Immature Permanent Teeth: A Meta-Analysis of Clinical Efficacy

Longitudinal periapical radiographic evaluation of apexification, vital pulpotomy, and revascularization in immature permanent teeth: a retrospective comparative study

Revisiting the role of IL-1 signaling in the development of apical periodontitis

Sex-specific nociceptor modulation of the apical periodontitis transcriptome

Outcomes of root canal treatments with three different sealers for 120 fractured maxillary fourth premolar teeth in small-to medium-sized dogs