Prebiotic Chemistry | List of Frontiers open access articles

Mini Review

Published on 25 Feb 2026

Chemistry of the origins of life: how prebiotic chemistry can be approached by computational quantum methods

in Astrobiology

Ana Luiza Quilici
Marcelo V. P. De Sousa
Ataualpa A. C. Braga

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2026.1736181

595 views

Perspective

Published on 05 Apr 2024

The spark of life: discharge physics as a key aspect of the Miller–Urey experiment

in Interdisciplinary Physics

Savino Longo

Frontiers in Physics

doi 10.3389/fphy.2024.1392578

7,834 views
1 citation

Original Research

Published on 30 Mar 2023

A Proterozoic microbial origin of extant cyanide-hydrolyzing enzyme diversity

in Evolutionary and Genomic Microbiology

Sarah L. Schwartz
L. Thiberio Rangel
Jack G. Payette
Gregory P. Fournier

Frontiers in Microbiology

doi 10.3389/fmicb.2023.1130310

4,140 views
2 citations

Review

Published on 13 Jul 2022

Prebiotic Chemistry: The Role of Trimetaphosphate in Prebiotic Chemical Evolution

in Chemical Biology

Dingwei Gan
Jianxi Ying
Yufen Zhao

Frontiers in Chemistry

doi 10.3389/fchem.2022.941228

5,666 views
22 citations

Original Research

Published on 13 May 2022

Formamide-Based Post-impact Thermal Prebiotic Synthesis in Simulated Craters: Intermediates, Products and Mechanism

in Astrobiology

Martin Ferus
Antonín Knížek
Lukáš Petera
Adam Pastorek
Jana Hrnčířová
Luboš Jankovič
Ondřej Ivanek
Jiří Šponer
Anna Křivková
Homa Saeidfirozeh

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2022.882145

4,082 views
9 citations

Perspective

Published on 21 Nov 2025

The role of magnetite-rich environments in prebiotic chemistry and astrobiology: insights into serpentinization processes on Mars

in Astrobiology

Varsha M. Nair
Sana Hasan Jagmag
Amit Basu Sarbadhikari

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2025.1622043

2,029 views

Original Research

Published on 18 Sep 2020

Reactivity of Cyanide at Water-Ice Interfaces: Implications for the Search for Organics on Icy Worlds

in Astrobiology

Margarita R. Marín-Yaseli
Elena González-Toril
Marta Ruiz-Bermejo

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2020.519017

4,124 views
9 citations

Review

Published on 04 Feb 2026

Prebiotic chemistry and origin of living beings: current state, scientific perspectives and (bio)ethical issues

in Astrobiology

Rodrigo Siqueira-Batista
Ricardo Alves-Ferreira
Rafaela Lacerda Pedra Maroca-de-Avelar
Maria Isabel Cristina Batista Mayrink
Eugênio Silva
Felipe Gómez

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2025.1682489

1,614 views

Original Research

Accepted on 12 Feb 2026

East Meridiani Planum's Karst Geomorphology and Biosignature Preservation Potential: A Multi-Criteria Landing Site Analysis

in Astrobiology

Shaoqiu Wang

Frontiers in Astronomy and Space Sciences

112 views

Review

Published on 05 Jan 2023

Setting the geological scene for the origin of life and continuing open questions about its emergence

in Astrobiology

Frances Westall
André Brack
Alberto G. Fairén
Mitchell D. Schulte

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2022.1095701

26,018 views
32 citations

Review

Published on 05 Dec 2022

Can prebiotic systems survive in the wild? An interference chemistry approach

in Geochemistry

Craig R. Walton
Paul Rimmer
Oliver Shorttle

Frontiers in Earth Science

doi 10.3389/feart.2022.1011717

4,028 views
14 citations

Review

Published on 08 Feb 2024

Inorganic Fe-O and Fe-S oxidoreductases: paradigms for prebiotic chemistry and the evolution of enzymatic activity in biology

in Astrochemistry

Xiao-Lan Huang
Jeffrey R. Harmer
Gerhard Schenk
Gordon Southam

Frontiers in Chemistry

doi 10.3389/fchem.2024.1349020

8,942 views
12 citations

Review

Published on 21 Aug 2024

Observations of phosphorus-bearing molecules in the interstellar medium

in Astrochemistry

Francesco Fontani

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2024.1451127

5,075 views
10 citations

Original Research

Published on 03 Apr 2023

Evaluating the abiotic synthesis potential and the stability of building blocks of life beneath an impact-induced steam atmosphere

in Extreme Microbiology

Zongbin Zhang
Haofan Jiang
Pengcheng Ju
Lu Pan
Joti Rouillard
Gentao Zhou
Fang Huang
Jihua Hao

Frontiers in Microbiology

doi 10.3389/fmicb.2023.1032073

4,744 views
1 citation

Original Research

Published on 08 Jul 2022

Molecular Precursors of the RNA-World in Space: New Nitriles in the G+0.693−0.027 Molecular Cloud

in Astrochemistry

Víctor M. Rivilla
Izaskun Jiménez-Serra
Jesús Martín-Pintado
Laura Colzi
Belén Tercero
Pablo de Vicente
Shaoshan Zeng
Sergio Martín
Juan García de la Concepción
Luca Bizzocchi

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2022.876870

18,313 views
47 citations

Articles

Chemistry of the origins of life: how prebiotic chemistry can be approached by computational quantum methods

The spark of life: discharge physics as a key aspect of the Miller–Urey experiment

A Proterozoic microbial origin of extant cyanide-hydrolyzing enzyme diversity

Prebiotic Chemistry: The Role of Trimetaphosphate in Prebiotic Chemical Evolution

Formamide-Based Post-impact Thermal Prebiotic Synthesis in Simulated Craters: Intermediates, Products and Mechanism

The role of magnetite-rich environments in prebiotic chemistry and astrobiology: insights into serpentinization processes on Mars

Reactivity of Cyanide at Water-Ice Interfaces: Implications for the Search for Organics on Icy Worlds

Prebiotic chemistry and origin of living beings: current state, scientific perspectives and (bio)ethical issues

East Meridiani Planum's Karst Geomorphology and Biosignature Preservation Potential: A Multi-Criteria Landing Site Analysis

Setting the geological scene for the origin of life and continuing open questions about its emergence

Can prebiotic systems survive in the wild? An interference chemistry approach

Inorganic Fe-O and Fe-S oxidoreductases: paradigms for prebiotic chemistry and the evolution of enzymatic activity in biology

Observations of phosphorus-bearing molecules in the interstellar medium

Evaluating the abiotic synthesis potential and the stability of building blocks of life beneath an impact-induced steam atmosphere

Molecular Precursors of the RNA-World in Space: New Nitriles in the G+0.693−0.027 Molecular Cloud