Pyrazole | List of Frontiers open access articles

Original Research

Published on 16 Feb 2024

Choline chloride/urea as a green and efficient deep eutectic solvent in three-component and four-component synthesis of novel pyrazole and pyrano[2,3-c] pyrazole derivatives with antibacterial and antifungal activity

in Organic Chemistry

Israa Habeeb Naser
Hassan Thoulfikar A. Alamir
Ali Hisham Al-Shukarji
Batool Ali Ahmed
Talal Aziz Qassem
Maher Kamal
Tahani M. Almeleebia
Enas R. Alwaily
Eftikhaar Hasan Kadhum
Ahmed Alawadi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1342784

9,385 views
14 citations

Original Research

Published on 07 Oct 2020

Antiparasitic Behavior of Trifluoromethylated Pyrazole 2-Amino-1,3,4-thiadiazole Hybrids and Their Analogues: Synthesis and Structure-Activity Relationship

in Translational Pharmacology

Jeniffer do Nascimento Ascencio Camargo
Karlos Eduardo Pianoski
Mariellen Guilherme dos Santos
Danielle Lazarin-Bidóia
Hélito Volpato
Sidnei Moura
Celso Vataru Nakamura
Fernanda Andreia Rosa

Frontiers in Pharmacology

doi 10.3389/fphar.2020.591570

5,767 views
23 citations

Original Research

Published on 29 Mar 2022

PCW-1001, a Novel Pyrazole Derivative, Exerts Antitumor and Radio-Sensitizing Activities in Breast Cancer

in Breast Cancer

Minsung Kang
Navin Pandit
Ah-Young Kim
Suk Joon Cho
Young-Ju Kwon
Jiyeon Ahn
Kyu Myung Lee
Sangwook Wu
Jeong Su Oh
Kwan-Young Jung

Frontiers in Oncology

doi 10.3389/fonc.2022.835833

7,464 views
8 citations

Original Research

Published on 01 Oct 2024

Copper pyrazole addition regulates soil mineral nitrogen turnover by mediating microbial traits

in Terrestrial Microbiology

Yuming Wang
Wenling Zhong
Xiwen Zhang
Minghui Cao
Zheng Ni
Mengxia Zhang
Jiangye Li
Yan Duan
Lifang Wu

Frontiers in Microbiology

doi 10.3389/fmicb.2024.1433816

2,571 views
2 citations

Mini Review

Published on 10 May 2021

Heterocyclic Compounds: Pharmacology of Pyrazole Analogs From Rational Structural Considerations

in Experimental Pharmacology and Drug Discovery

Rafael Fernades Costa
Larissa Córdova Turones
Keilah Valéria Naves Cavalcante
Ismael Aureliano Rosa Júnior
Carlos Henrique Xavier
Lucimar Pinheiro Rosseto
Hamilton Barbosa Napolitano
Patrícia Ferreira da Silva Castro
Marcos Luiz Ferreira Neto
Gustavo Mota Galvão

Frontiers in Pharmacology

doi 10.3389/fphar.2021.666725

61,069 views
103 citations

Original Research

Published on 28 Jan 2020

NSC 18725, a Pyrazole Derivative Inhibits Growth of Intracellular Mycobacterium tuberculosis by Induction of Autophagy

in Antimicrobials, Resistance and Chemotherapy

Garima Arora
Gagandeep
Assirbad Behura
Tannu Priya Gosain
Ravi P. Shaliwal
Saqib Kidwai
Padam Singh
Shamseer Kulangara Kandi
Rohan Dhiman
Diwan S. Rawat

Frontiers in Microbiology

doi 10.3389/fmicb.2019.03051

9,993 views
28 citations

Original Research

Published on 15 Nov 2021

Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole–Based RalA Inhibitors Against Hepatocellular Carcinoma

in Medicinal and Pharmaceutical Chemistry

Yuting Wang
Mingyao He
Xiang Li
Jinlong Chai
Qinglin Jiang
Cheng Peng
Gu He
Wei Huang

Frontiers in Chemistry

doi 10.3389/fchem.2021.700956

11,740 views
9 citations

Original Research

Published on 17 Apr 2024

Acyl pyrazole sulfonamides as new antidiabetic agents: synthesis, glucosidase inhibition studies, and molecular docking analysis

in Organic Chemistry

Atteeque Ahmed
Sumera Zaib
Mashooq Ahmad Bhat
Aamer Saeed
Muhammad Zain Altaf
Fatima Tuz Zahra
Ghulam Shabir
Nehal Rana
Imtiaz Khan

Frontiers in Chemistry

doi 10.3389/fchem.2024.1380523

10,960 views
16 citations

Original Research

Published on 24 Jan 2020

Novel Anticancer Fused Pyrazole Derivatives as EGFR and VEGFR-2 Dual TK Inhibitors

in Medicinal and Pharmaceutical Chemistry

Nashwa M. Saleh
Marwa G. El-Gazzar
Hala M. Aly
Rana A. Othman

Frontiers in Chemistry

doi 10.3389/fchem.2019.00917

21,698 views
133 citations

Original Research

Published on 24 Feb 2026

Prenatal alcohol exposure induces anxiety and depressive-like behaviors with deficits in growth and food intake in mice

in Embryonic Development

Kamal Smimih
Bilal El-Mansoury
Mohamed Marghich
Chaima Azzouhri
Nadia Zouhairi
Mustapha Agnaou
Morad Guennouni
Naima Fdil
Abdelali Bitar
Mahmoud M. A. Abulmeaty

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1742806

841 views

Original Research

Published on 02 Oct 2024

Optimizing nitrogen fertilization in maize: the impact of nitrification inhibitors, phosphorus application, and microbial interactions on enhancing nutrient efficiency and crop performance

in Plant Nutrition

Ali Malakshahi Kurdestani
Davide Francioli
Reiner Ruser
Alessandro Piccolo
Niels Julian Maywald
Xinping Chen
Torsten Müller

Frontiers in Plant Science

doi 10.3389/fpls.2024.1451573

4,035 views
5 citations

Original Research

Published on 26 Sep 2023

Pyrazole‐promoted synthesis of pyrrolo[3,4‐c] quinoline-1,3‐diones in a novel diketene-based reaction

in Organic Chemistry

Atieh Rezvanian
Zahra Esfandsar

Frontiers in Chemistry

doi 10.3389/fchem.2023.1219986

10,617 views

Review

Published on 09 Sep 2014

Pyrazoles as potential anti-angiogenesis agents: a contemporary overview

in Medicinal and Pharmaceutical Chemistry

Konstantinos M. Kasiotis
Evangelia N. Tzanetou
Serkos A. Haroutounian

Frontiers in Chemistry

doi 10.3389/fchem.2014.00078

10,742 views
67 citations

Original Research

Published on 13 Jun 2023

Synthesis of novel Fe3O4 nanostructures surrounded by Ti-MOF nanostructures as bioactive and efficient catalysts in three-component synthesis of new pyrazole derivatives

in Polymeric and Composite Materials

Balsam Qubais Saeed
Ibrahem Waleed
Hussein Humedy Chlib Alkaaby
Sabrean Farhan Jawad
Usama S. Altimari
Ziyad Shihab Ahmed AL-Sarraj
Ruwaida T. Shbeeb
Salema K. Hadrawi
Muath Suliman
Mohammad Y. Alshahrani

Frontiers in Materials

doi 10.3389/fmats.2023.1156702

3,143 views
9 citations

Original Research

Published on 22 Jun 2022

Synthesis and Bioactivity of Novel Sulfonate Scaffold-Containing Pyrazolecarbamide Derivatives as Antifungal and Antiviral Agents

in Organic Chemistry

Zhi-Wei Lei
Jianmei Yao
Huifang Liu
Chiyu Ma
Wen Yang

Frontiers in Chemistry

doi 10.3389/fchem.2022.928842

6,240 views
11 citations

Original Research

Published on 15 May 2024

Melamine phosphate-modified magnetic chitosan: a novel biocompatible catalyst for the synthesis of biological tetrahydrodipyrazolopyridine and pyrazolopyranopyrimidine derivatives

in Catalytic Reactions and Chemistry

Maryam Mousavi-Ebadi
Javad Safaei-Ghomi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1395008

3,154 views
10 citations

Articles

Choline chloride/urea as a green and efficient deep eutectic solvent in three-component and four-component synthesis of novel pyrazole and pyrano[2,3-c] pyrazole derivatives with antibacterial and antifungal activity

Antiparasitic Behavior of Trifluoromethylated Pyrazole 2-Amino-1,3,4-thiadiazole Hybrids and Their Analogues: Synthesis and Structure-Activity Relationship

PCW-1001, a Novel Pyrazole Derivative, Exerts Antitumor and Radio-Sensitizing Activities in Breast Cancer

Copper pyrazole addition regulates soil mineral nitrogen turnover by mediating microbial traits

Heterocyclic Compounds: Pharmacology of Pyrazole Analogs From Rational Structural Considerations

NSC 18725, a Pyrazole Derivative Inhibits Growth of Intracellular Mycobacterium tuberculosis by Induction of Autophagy

Design, Synthesis, and Biological Evaluation of Pyrano[2,3-c]-pyrazole–Based RalA Inhibitors Against Hepatocellular Carcinoma

Acyl pyrazole sulfonamides as new antidiabetic agents: synthesis, glucosidase inhibition studies, and molecular docking analysis

Novel Anticancer Fused Pyrazole Derivatives as EGFR and VEGFR-2 Dual TK Inhibitors

Prenatal alcohol exposure induces anxiety and depressive-like behaviors with deficits in growth and food intake in mice

Optimizing nitrogen fertilization in maize: the impact of nitrification inhibitors, phosphorus application, and microbial interactions on enhancing nutrient efficiency and crop performance

Pyrazole‐promoted synthesis of pyrrolo[3,4‐c] quinoline-1,3‐diones in a novel diketene-based reaction

Pyrazoles as potential anti-angiogenesis agents: a contemporary overview

Synthesis of novel Fe3O4 nanostructures surrounded by Ti-MOF nanostructures as bioactive and efficient catalysts in three-component synthesis of new pyrazole derivatives

Synthesis and Bioactivity of Novel Sulfonate Scaffold-Containing Pyrazolecarbamide Derivatives as Antifungal and Antiviral Agents

Melamine phosphate-modified magnetic chitosan: a novel biocompatible catalyst for the synthesis of biological tetrahydrodipyrazolopyridine and pyrazolopyranopyrimidine derivatives