Second Order System | List of Frontiers open access articles

Review

Published on 14 May 2026

Metabolic reprogramming in sepsis-associated encephalopathy: emerging mechanisms, candidate biomarkers, and future therapeutic directions

in Precision Medicine

Mei Huang
Weiwei Qian
Daxiu Lin
Yihua Zeng
Yan Zhou
Shurong Zhang
Yaling Luo
Zhi Li
Xiaodong Du

Frontiers in Medicine

doi 10.3389/fmed.2026.1821690

178 views

Original Research

Published on 14 May 2026

Relationship between hemoglobin levels and diabetic retinopathy in Chinese type 2 diabetes mellitus populations: a cross-sectional study

in Clinical Diabetes

Jinghan Zheng
Jingwei Chi
Kui Che
Qidong Zheng
Yangang Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1800238

227 views

Original Research

Published on 14 May 2026

Metabolic effects and pharmacokinetics of oral cannabidiol (CBD) in Connemara ponies following 21 days of treatment

in Veterinary Pharmacology and Toxicology

Kata Wermer
Róbert Berkecz
István Ilisz
Dezső Csupor
Nóra Ágh
Anita Sztojkov-Ivanov
Dániel Cserhalmi
Ákos Jerzsele
Orsolya Korbacska-Kutasi

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1813917

267 views

Original Research

Published on 14 May 2026

Health Resorts as an integrated community healthcare model for fibromyalgia syndrome: a strategic SWOT analysis

in Rheumatology

Gianluca Regazzo
Francesco Piccione
Aristide Roberto Gravina
Stefano Masiero

Frontiers in Medicine

doi 10.3389/fmed.2026.1736755

364 views

Review

Published on 14 May 2026

T-cell exhaustion in tumor immunology: mechanisms, heterogeneity, and therapeutic strategies

in Cancer Immunity and Immunotherapy

Ruoxuan Wang
Yingjie Guo

Frontiers in Immunology

doi 10.3389/fimmu.2026.1841281

538 views

Original Research

Published on 14 May 2026

Characterization of the tumor microenvironment in locally advanced gastric cancer and identification of spatially predictive biomarkers associated with beneficial neoadjuvant immunochemotherapy

in Cancer Immunity and Immunotherapy

Xiaohong Xu
Jun Fan
Li Peng
Zhengkai Xiang
Danju Luo
Chenggong Ma
Bo Huang
Xiu Nie
Xiaochuan Dong

Frontiers in Immunology

doi 10.3389/fimmu.2026.1823308

140 views

Mini Review

Published on 14 May 2026

Antibody targeting of the TNF–TNFR2 axis to overcome tumor immune resistance

in Cancer Immunity and Immunotherapy

Xiaozhen Kang
Xiangmin Tong
Shibing Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1809305

251 views

Policy and Practice Reviews

Published on 14 May 2026

Navigating marine litter governance: loopholes and strategic recommendations for the EU policy framework

in Marine Affairs and Policy

Demetra L. Orthodoxou
Xenia I. Loizidou

Frontiers in Marine Science

doi 10.3389/fmars.2026.1810562

217 views

Case Report

Published on 14 May 2026

MYBPC1-associated congenital myopathy with tremor: further delineation of the clinical and pathological phenotype in the first Italian case

in Genetics of Common and Rare Diseases

Daniele Velardo
Claudia Alberti
Delia Gagliardi
Roberto Del Bo
Patrizia Ciscato
Laura Napoli
Simona Zanotti
Michela Ripolone
Michele Giovanni Croce
Giuseppe Cosentino

Frontiers in Genetics

doi 10.3389/fgene.2026.1809063

344 views

Original Research

Published on 14 May 2026

Association between physical activity and inflammatory bowel disease: a prospective cohort study

in Public Health and Nutrition

Yitian Wei
Binbin He
Ge Zhang
Haitao Chen
Tuojian Li

Frontiers in Public Health

doi 10.3389/fpubh.2026.1819729

295 views

Original Research

Published on 14 May 2026

Migraine as an occupational health risk among nurses in Qassim region, Saudi Arabia: a multicenter study of risk perceptions and associated factors

in Occupational Health and Safety

Shereen Ahmed A. Qalawa
Mohamed Goda Elbqry
Fatma Mohamed Elmansy
Samia Eaid Elgazzar
Fatma S O Ashmieg
Saddam Ahmed Al-Ahdal
Aljoud Abdulrahman Alshitwy

Frontiers in Public Health

doi 10.3389/fpubh.2026.1789630

275 views

Original Research

Published on 14 May 2026

Development and validation of a Vero cell DNA standard for residual DNA measurement suitable for quantitative PCR method

in Microbiotechnology

Danhua Zhao
Yunpeng Wang
Xiaohong Wu
Leitai Shi
Jia Li
Yuhua Li
Shouchun Cao

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1708044

364 views

Original Research

Published on 14 May 2026

Attitudes toward smart sports technologies and artificial intelligence: an examination from cognitive, affective and behavioral dimensions

in Digital Public Health

Irfan Kara
Yunus Sahinler
Mustafa Can Koc
Mustafa Yasar Sahin
Kenan Sebin
Laurentiu-Gabriel Talaghir
Teodora Mihaela Iconomescu
Liliana Nanu
Ștefan Cristian Liușnea
Gabriel Marian Manolache

Frontiers in Public Health

doi 10.3389/fpubh.2026.1830510

277 views

Original Research

Published on 14 May 2026

Cost-effectiveness of 6-year school-based caries preventive interventions in Thailand: a system dynamics modeling study

in Health Economics

Tin Htet Oo
Songchai Thitasomakul
Phongpat Sontamino
Sukanya Tianviwat

Frontiers in Public Health

doi 10.3389/fpubh.2026.1744986

284 views

Original Research

Published on 14 May 2026

Predictive performance of cardiometabolic indices for prediabetes progression to diabetes and reversion to normoglycemia in adults: a cohort study

in Nutrition and Metabolism

Yilin Zhu
Yangxuan He
Shusheng Fang
Hong Chen
Jingshan Jiang
Yunxiang Ming
Song Leng

Frontiers in Nutrition

doi 10.3389/fnut.2026.1784247

140 views

Original Research

Published on 14 May 2026

Probiotic properties of Bacillus subtilis isolates from neonatal meconium

in Food Microbiology

Saurabh Kumar Singh
Sadhana Sathaye
Jayraj Doshi

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1804128

278 views

Articles

Metabolic reprogramming in sepsis-associated encephalopathy: emerging mechanisms, candidate biomarkers, and future therapeutic directions

Relationship between hemoglobin levels and diabetic retinopathy in Chinese type 2 diabetes mellitus populations: a cross-sectional study

Metabolic effects and pharmacokinetics of oral cannabidiol (CBD) in Connemara ponies following 21 days of treatment

Health Resorts as an integrated community healthcare model for fibromyalgia syndrome: a strategic SWOT analysis

T-cell exhaustion in tumor immunology: mechanisms, heterogeneity, and therapeutic strategies

Characterization of the tumor microenvironment in locally advanced gastric cancer and identification of spatially predictive biomarkers associated with beneficial neoadjuvant immunochemotherapy

Antibody targeting of the TNF–TNFR2 axis to overcome tumor immune resistance

Navigating marine litter governance: loopholes and strategic recommendations for the EU policy framework

MYBPC1-associated congenital myopathy with tremor: further delineation of the clinical and pathological phenotype in the first Italian case

Association between physical activity and inflammatory bowel disease: a prospective cohort study

Migraine as an occupational health risk among nurses in Qassim region, Saudi Arabia: a multicenter study of risk perceptions and associated factors

Development and validation of a Vero cell DNA standard for residual DNA measurement suitable for quantitative PCR method

Attitudes toward smart sports technologies and artificial intelligence: an examination from cognitive, affective and behavioral dimensions

Cost-effectiveness of 6-year school-based caries preventive interventions in Thailand: a system dynamics modeling study

Predictive performance of cardiometabolic indices for prediabetes progression to diabetes and reversion to normoglycemia in adults: a cohort study

Probiotic properties of Bacillus subtilis isolates from neonatal meconium

Metabolic effects and pharmacokinetics of oral cannabidiol (CBD) in Connemara ponies following 21 days of treatment