Sphincter Preservation | List of Frontiers open access articles

Original Research

Published on 21 Oct 2022

Quality of life and function after rectal cancer surgery with and without sphincter preservation

in Gastrointestinal Cancers: Colorectal Cancer

Emmanouil P. Pappou
Larissa K. Temple
Sujata Patil
J. Joshua Smith
Iris H. Wei
Garrett M. Nash
José G. Guillem
Maria Widmar
Martin R. Weiser
Philip B. Paty

Frontiers in Oncology

doi 10.3389/fonc.2022.944843

6,961 views
29 citations

Clinical Trial

Published on 07 Nov 2024

Conformal proctectomy with sphincter preservation retains acceptable defecation functions in very low rectal cancer male patients

in Surgical Oncology

Weijie Chen
Xiao Zhang
Xiaoyuan Qiu
Jiaolin Zhou

Frontiers in Oncology

doi 10.3389/fonc.2024.1478467

1,748 views
2 citations

Original Research

Published on 06 Oct 2023

Can neoadjuvant chemoradiotherapy combined with immunotherapy benefit patients with microsatellite stable locally advanced rectal cancer? a pooled and integration analysis

in Gastrointestinal Cancers: Colorectal Cancer

Yumin Yue
Min Cheng
Xiaohui Xi
Quan Wang
Mingtian Wei
Bobo Zheng

Frontiers in Oncology

doi 10.3389/fonc.2023.1280995

2,992 views
4 citations

Systematic Review

Published on 08 Feb 2022

Efficacy and Safety of Sphincter-Preserving Surgery in the Treatment of Complex Anal Fistula: A Network Meta-Analysis

in Visceral Surgery

Hua Huang
Lijiang Ji
Yunfei Gu
Youran Li
Shanshan Xu

Frontiers in Surgery

doi 10.3389/fsurg.2022.825166

7,045 views
47 citations

Case Report

Published on 24 Jan 2025

Long term survival following cryoablation with adjuvant Toripalimab for anorectal malignant melanoma: a case report

in Cancer Immunity and Immunotherapy

Xuejun Jiang
Zujin Ji
Peng Li
Fangjun Yuan
Xinyi Lei
Yong Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1465645

2,205 views
1 citation

Original Research

Published on 26 Jan 2023

Permanent stoma after sphincter preservation for rectal cancer. A situation that occurs more often than you might think

in Gastrointestinal Cancers: Colorectal Cancer

Flavie Thomas
Benjamin Menahem
Gil Lebreton
Karine Bouhier-Leporrier
Olivier Dejardin
Arnaud Alves

Frontiers in Oncology

doi 10.3389/fonc.2022.1056314

3,539 views
11 citations

Original Research

Published on 09 Dec 2025

Efficacy and toxicity of neoadjuvant radiotherapy with concomitant dose escalation for rectal cancer

in Radiation Oncology

Peng Wang
Kai Liu
Xiaoliang Liu
Weiping Wang
Dingchao Liu
Yidi Wang
Shuai Sun
Ke Hu

Frontiers in Oncology

doi 10.3389/fonc.2025.1725405

783 views

Review

Published on 24 Mar 2023

Total neoadjuvant treatment and PD-1/PD-L1 checkpoint inhibitor in locally advanced rectal cancer

in Cancer Immunity and Immunotherapy

Weiwei Xiao
Huilong Luo
Ye Yao
Yaqin Wang
Shuang Liu
Rui Sun
Gong Chen

Frontiers in Immunology

doi 10.3389/fimmu.2023.1149122

9,820 views
12 citations

Original Research

Published on 21 Jan 2026

Robotic evolution from Si to Xi in rectal cancer assessing operative performance and oncological outcomes

in Surgical Oncology

Wenpeng Wang
Shan Gao
Jinghao Huang
Duo Yun
Jiefu Wang

Frontiers in Surgery

doi 10.3389/fsurg.2025.1668213

524 views

Original Research

Published on 14 Jan 2022

Neoadjuvant PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy in Locally Advanced Anal Canal Squamous Cell Carcinoma Patients: Antitumor Efficacy, Safety and Biomarker Analysis

in Cancer Immunity and Immunotherapy

WeiWei Xiao
Yan Yuan
SuiHai Wang
Zhidong Liao
PeiQiang Cai
BaoQing Chen
Rong Zhang
Fang Wang
ZhiFan Zeng
YuanHong Gao

Frontiers in Immunology

doi 10.3389/fimmu.2021.798451

8,593 views
13 citations

Original Research

Published on 05 Feb 2026

Health-related quality of life scores of ultralow rectal cancer patients after conformal sphincter preservation operation compared to newly derived preoperative EORTC QLQ-C30, CR38 reference values and EORTC QLQ-C30 norm

in Gastrointestinal Cancers: Colorectal Cancer

Hai‐bo Ding
Ge Sun
Guan‐yu Yu
Xian‐hua Gao
Zheng Lou
Zheng Kuo
Hai‐feng Gong
Xiao‐ming Zhu
Wei Zhang

Frontiers in Oncology

doi 10.3389/fonc.2026.1724255

456 views

Original Research

Published on 21 Oct 2020

Oncological Outcomes of Robotic-Assisted Surgery With High Dissection and Selective Ligation Technique for Sigmoid Colon and Rectal Cancer

in Surgical Oncology

Tzu-Chieh Yin
Wei-Chih Su
Po-Jung Chen
Tsung-Kun Chang
Yen-Cheng Chen
Ching-Chun Li
Yi-Chien Hsieh
Hsiang-Lin Tsai
Ching-Wen Huang
Jaw-Yuan Wang

Frontiers in Oncology

doi 10.3389/fonc.2020.570376

4,684 views
13 citations

Study Protocol

Published on 08 Aug 2025

Total neoadjuvant chemoradiotherapy plus anti PD-1 for mid-to-low locally advanced rectal cancer: study protocol of a prospective, single arm, phase II study (STARS - RC06)

in Cancer Immunity and Immunotherapy

Meichen Gu
Yuchen Guo
Liang He
Xuan Sun
Tingting Liang
Zhuo Wang
Ying Li
Zheng Liu
Jingyu Wang
Xiang Qiu

Frontiers in Oncology

doi 10.3389/fonc.2025.1594927

3,246 views

Original Research

Published on 08 Dec 2022

Trends of sphincter-preserving surgeries for low lying rectal cancer: A 20-year experience in China

in Gastrointestinal Cancers: Colorectal Cancer

Kuo Zheng
Qingqing Hu
Guanyu Yu
Leqi Zhou
Yuting Yao
Yuan Zhou
Hao Wang
Liqiang Hao
Enda Yu
Zheng Lou

Frontiers in Oncology

doi 10.3389/fonc.2022.996866

5,528 views
14 citations

Original Research

Published on 24 Dec 2024

Total neoadjuvant therapy based on short-course radiotherapy versus standard long-course chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis of randomized controlled trials

in Radiation Oncology

Wenji Pu
Wenqi Chen
Haiman Jing
Jishi Li
Yong Jiang
Shasha Li
Weijie Wen
Zhiyuan Xu
Jing Jin

Frontiers in Oncology

doi 10.3389/fonc.2024.1515756

6,321 views
1 citation

Systematic Review

Published on 26 Jun 2025

Neoadjuvant chemotherapy versus long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis of 5,168 cases

in Gastrointestinal Cancers: Colorectal Cancer

Wenjie Zhou
Xueting Wang
Jie Dan
Minjie Zhu
Qian Liao
Ke Liu
Jiangpeng Li
Xianhong Jiang
Yonghong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1542885

2,479 views
1 citation

Articles

Quality of life and function after rectal cancer surgery with and without sphincter preservation

Conformal proctectomy with sphincter preservation retains acceptable defecation functions in very low rectal cancer male patients

Can neoadjuvant chemoradiotherapy combined with immunotherapy benefit patients with microsatellite stable locally advanced rectal cancer? a pooled and integration analysis

Efficacy and Safety of Sphincter-Preserving Surgery in the Treatment of Complex Anal Fistula: A Network Meta-Analysis

Long term survival following cryoablation with adjuvant Toripalimab for anorectal malignant melanoma: a case report

Permanent stoma after sphincter preservation for rectal cancer. A situation that occurs more often than you might think

Efficacy and toxicity of neoadjuvant radiotherapy with concomitant dose escalation for rectal cancer

Total neoadjuvant treatment and PD-1/PD-L1 checkpoint inhibitor in locally advanced rectal cancer

Robotic evolution from Si to Xi in rectal cancer assessing operative performance and oncological outcomes

Neoadjuvant PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy in Locally Advanced Anal Canal Squamous Cell Carcinoma Patients: Antitumor Efficacy, Safety and Biomarker Analysis

Health-related quality of life scores of ultralow rectal cancer patients after conformal sphincter preservation operation compared to newly derived preoperative EORTC QLQ-C30, CR38 reference values and EORTC QLQ-C30 norm

Oncological Outcomes of Robotic-Assisted Surgery With High Dissection and Selective Ligation Technique for Sigmoid Colon and Rectal Cancer

Total neoadjuvant chemoradiotherapy plus anti PD-1 for mid-to-low locally advanced rectal cancer: study protocol of a prospective, single arm, phase II study (STARS - RC06)

Trends of sphincter-preserving surgeries for low lying rectal cancer: A 20-year experience in China

Total neoadjuvant therapy based on short-course radiotherapy versus standard long-course chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis of randomized controlled trials

Neoadjuvant chemotherapy versus long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis of 5,168 cases