Systems Thinking | List of Frontiers open access articles

Original Research

Accepted on 14 Oct 2025

Construction of EpCAM Overexpression and Knockdown Vectors and Their Implications in Colorectal Cancer Research

in Genome Editing in Cancer and Immunology

Bingping WANG
Jinkai Duan
Jie Zhou
Hulin Ma
Meng Ren
Liangquan Chen
Rina Su
Hao Zhang
Shuang Zhang
Yanwei Gao

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1679698

Perspective

Accepted on 14 Oct 2025

Identifying and addressing the components of extreme physical-oceanographical events for improved risk management in coastal systems

in Marine Biogeochemistry

Eric 'Pieter Achterberg
Fabian Rackelmann
Ananya Ramesh
Jack O'Connor
Ovidio García-Oliva
Saranya Jayachandran
Viktoria Wichert
Xiangyu Li
Kaveh Purkiani
David Michael Needham

Frontiers in Marine Science

doi 10.3389/fmars.2025.1681652

Original Research

Accepted on 14 Oct 2025

Simultaneous Bilateral Intravitreal Anti-Vascular Endothelial Growth Factor Injections from One Vial for Diabetic Macular Edema: A Retrospective Analysis

in Ophthalmology

Yuanmin Dai
Jixian Lou
Jiquan Wen
Guanlu Liang
Jiehui Xu
Juanjuan Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1712378

Original Research

Accepted on 14 Oct 2025

Neuroprotective Mechanisms of Valproic Acid and Alpha-Lipoic Acid in ALS: A Network Pharmacology-Based Investigation

in Neuropharmacology

Dongmei Zhang
Ling Han
Wenmo Zhang
Di Wang
Di Huo
Xingli Tan
Xiaoli Su
Ming Wang
Jing Xu
Jiling Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681929

Opinion

Accepted on 14 Oct 2025

Reimagining the Frailty Review: Meaning, Metrics, and the Missed Opportunity in Global Ageing Care

in Family Medicine and Primary Care

Waseem Jerjes
Daniel Harding
Arnoupe Jhass

Frontiers in Medicine

doi 10.3389/fmed.2025.1620193

Editorial

Accepted on 14 Oct 2025

Editorial: Practices for Gender Equality: Teachers' Sense of Efficacy

in Teacher Education

Tanya Pinkerton
Wendy Peia Oakes
Alexander Kurz
Abdessamad Fatmi
Ying-Chih Chen
Nicole L Thompson
Setrag Hovspeian

Frontiers in Education

doi 10.3389/feduc.2025.1723688

Original Research

Accepted on 14 Oct 2025

Genetically Engineered Pseudomonas aeruginosa with Lipase Regulation for Production of Rhamnolipids from Waste Frying Oil

in Systems Microbiology

Ruijuan Li
Runyu Yang
Yitong Shi
Jinyu Bian
Mengxiao Sun
Junchi Ma
Cailing Ren
Xueyan Feng
Yun Wang
Yuanhui Yang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1691217

Original Research

Accepted on 14 Oct 2025

Multi-Omics Reveals the Regulatory Effects of Chinese Herbal medicine Substrates on Secondary Metabolite Biosynthesis in Inonotus glomeratus

in Microbial Physiology and Metabolism

Chengbo Peng
Meng Meng
Xiaolong Yuan
Jiaojun Yu
Boyi Wang
Li Zhong
Yi Wang
Lu Li
Tingwen He
Yuan Zheng

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1658730

Editorial

Accepted on 14 Oct 2025

Editorial: The Important Role of the Early School Years for Reading, Writing, and Math Development: Assessment and Intervention at School Entry

in Teacher Education

Martin Schöfl
Christoph Weber
Susanne Seifert
Natalie Förster

Frontiers in Education

doi 10.3389/feduc.2025.1720577

Original Research

Accepted on 14 Oct 2025

A Mixed-Methods Investigation for Effects of Built Environments on Older People's Social Interaction in Care Homes

in Aging and Public Health

Chendi Wang
Yujian Pan
Xingjian LI
Shaohua QIANG

Frontiers in Public Health

doi 10.3389/fpubh.2025.1693935

Original Research

Accepted on 14 Oct 2025

The Smooth Transition Autoregressive Models for the Unemployment Rate of Latvia

in Statistics and Probability

Oksana Pavlenko

Frontiers in Applied Mathematics and Statistics

doi 10.3389/fams.2025.1673247

Original Research

Accepted on 14 Oct 2025

Exploring Whether Relationship Mobility and Goal Congruence in Travel Groups Enhance Tourists' Pro-Environmental Behaviors: New Insights from Social Cognitive Theory

in Environmental Psychology

Gao Junxi
Weiwei Deng

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1681160

Original Research

Accepted on 14 Oct 2025

Detecting Environmental Barriers Affecting Elderly Pedestrians via Gramian Angular Field-based CNN of Smartphone Sensor Data

in Aging and Public Health

Sungkook Hong
Hyunsoo Kim

Frontiers in Public Health

doi 10.3389/fpubh.2025.1697589

Review

Accepted on 14 Oct 2025

Immunotherapy of Chimeric Antigen Receptor NK cells: Status and its Promising Future

in Cancer Immunity and Immunotherapy

Fang Wang
Zhaoyuan Huang
Xiaoming Feng
Mingxia Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608277

Original Research

Accepted on 14 Oct 2025

Bacterial community composition, quantification of antibiotic resistance genes and antibiotic residues in wastewater treatment plant and receiving rivers

in Aquatic Microbiology

Karabo Tsholo
Lesego Molale-Tom
Suranie Horn
Cornelius Carlos Bezuidenhout

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1635253

Curriculum, Instruction, and Pedagogy

Accepted on 14 Oct 2025

Professional learning community to facilitate professional development for using digital technology in the classroom: A teacher-based program evaluation

in Teacher Education

Catalina Lomos
Harmen Schaap
J.W. (Hans) Luyten
Frauke Kesting
Filipe Lima da Cunha
Carole Frieseisen
Sibel Telli
Sam Fowler

Frontiers in Education

doi 10.3389/feduc.2025.1611730

Articles

Construction of EpCAM Overexpression and Knockdown Vectors and Their Implications in Colorectal Cancer Research

Identifying and addressing the components of extreme physical-oceanographical events for improved risk management in coastal systems

Simultaneous Bilateral Intravitreal Anti-Vascular Endothelial Growth Factor Injections from One Vial for Diabetic Macular Edema: A Retrospective Analysis

Neuroprotective Mechanisms of Valproic Acid and Alpha-Lipoic Acid in ALS: A Network Pharmacology-Based Investigation

Reimagining the Frailty Review: Meaning, Metrics, and the Missed Opportunity in Global Ageing Care

Editorial: Practices for Gender Equality: Teachers' Sense of Efficacy

Genetically Engineered Pseudomonas aeruginosa with Lipase Regulation for Production of Rhamnolipids from Waste Frying Oil

Multi-Omics Reveals the Regulatory Effects of Chinese Herbal medicine Substrates on Secondary Metabolite Biosynthesis in Inonotus glomeratus

Editorial: The Important Role of the Early School Years for Reading, Writing, and Math Development: Assessment and Intervention at School Entry

A Mixed-Methods Investigation for Effects of Built Environments on Older People's Social Interaction in Care Homes

The Smooth Transition Autoregressive Models for the Unemployment Rate of Latvia

Exploring Whether Relationship Mobility and Goal Congruence in Travel Groups Enhance Tourists' Pro-Environmental Behaviors: New Insights from Social Cognitive Theory

Detecting Environmental Barriers Affecting Elderly Pedestrians via Gramian Angular Field-based CNN of Smartphone Sensor Data

Immunotherapy of Chimeric Antigen Receptor NK cells: Status and its Promising Future

Bacterial community composition, quantification of antibiotic resistance genes and antibiotic residues in wastewater treatment plant and receiving rivers

Professional learning community to facilitate professional development for using digital technology in the classroom: A teacher-based program evaluation