Transcription Factor Activity | List of Frontiers open access articles

Original Research

Published on 14 Mar 2023

Transmission of stimulus-induced epigenetic changes through cell division is coupled to continuous transcription factor activity

in Molecular Innate Immunity

Sarah Sun
Raúl Aguirre-Gamboa
Luis B. Barreiro

Frontiers in Immunology

doi 10.3389/fimmu.2023.1129577

5,010 views
20 citations

Original Research

Published on 04 Dec 2020

Patient Stratification of Clear Cell Renal Cell Carcinoma Using the Global Transcription Factor Activity Landscape Derived From RNA-Seq Data

in Genitourinary Oncology

Yanyan Zhu
Shundong Cang
Bowang Chen
Yue Gu
Miaomiao Jiang
Junya Yan
Fengmin Shao
Xiaoyun Huang

Frontiers in Oncology

doi 10.3389/fonc.2020.526577

3,638 views
12 citations

Original Research

Published on 24 Jun 2021

MDM2 Binding Protein Induces the Resistance of Hepatocellular Carcinoma Cells to Molecular Targeting Agents via Enhancing the Transcription Factor Activity of the Pregnane X Receptor

in Molecular and Cellular Oncology

Qiyu Jiang
Yan Ma
Jingjing Han
Jingdong Chu
Xuemei Ma
Lijun Shen
Bo Liu
Bo-an Li
Jun Hou
Qian Bi

Frontiers in Oncology

doi 10.3389/fonc.2021.715193

3,914 views
19 citations

Review

Published on 22 Apr 2026

Mechanistic insights and molecular therapy for neuroendocrine prostate cancer

in Cancer Molecular Targets and Therapeutics

Yichen Niu
Senyu Zhang
Shouyi Zhang
Jun Tao
Yuyan Zhu

Frontiers in Oncology

doi 10.3389/fonc.2026.1806742

473 views

Original Research

Published on 20 Aug 2025

Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension

in Molecular Diagnostics and Therapeutics

Claudia Desireé Norzagaray-Valenzuela
Marco Antonio Valdez-Flores
Josue Camberos-Barraza
Alberto Kousuke De la Herrán-Arita
Juan Fidel Osuna-Ramos
Javier Magaña-Gómez
Carla Angulo-Rojo
Alma Marlene Guadrón-Llanos
Katia Aviña-Padilla
Loranda Calderón-Zamora

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1621413

3,632 views

Review

Published on 20 Aug 2024

Role of post-translational modifications of Sp1 in cancer: state of the art

in Cancer Cell Biology

Xutao Sun
Chengpu Xiao
Xinyang Wang
Siyu Wu
Zhendong Yang
Bowen Sui
Yunjia Song

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1412461

6,003 views
19 citations

Review

Published on 02 Nov 2021

Transcription Factor Control of Lymphatic Quiescence and Maturation of Lymphatic Neovessels in Development and Physiology

in Vascular Physiology

Zarah B. Tabrizi
Nada S. Ahmed
Joseph L. Horder
Sarah J. Storr
Andrew V. Benest

Frontiers in Physiology

doi 10.3389/fphys.2021.672987

7,026 views
10 citations

Original Research

Published on 08 Nov 2022

Identification of hub genes regulating the cell activity and function of adipose-derived stem cells under oxygen-glucose deprivation

in Molecular Diagnostics and Therapeutics

Zhenyu Yang
Wei Lu
Zuoliang Qi
Xiaonan Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1025690

2,658 views
2 citations

Original Research

Published on 11 Nov 2022

A joint transcriptional regulatory network and protein activity inference analysis identifies clinically associated master regulators for biliary atresia

in Pediatric Gastroenterology, Hepatology and Nutrition

Panpan Sun
Manhuan Xiao
Huadong Chen
Zhihai Zhong
Hong Jiang
Xuyang Feng
Zhenhua Luo

Frontiers in Pediatrics

doi 10.3389/fped.2022.1050326

3,019 views
2 citations

Original Research

Published on 07 Nov 2025

Transcriptome analysis of classical blood cells reveals downregulation of pro-inflammatory genes in the classical monocytes of long COVID patients

in Viral Immunology

Florian Fricke
Franz Mai
Christine Wossidlo
Felix Steinbeck
Wendy Bergmann-Ewert
Marcel Kordt
Karin Kraft
Britta Müller
Emil C. Reisinger
Brigitte Müller-Hilke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1710783

3,401 views
1 citation

Original Research

Published on 02 Apr 2025

Predicting fitness in Mycobacterium tuberculosis with transcriptional regulatory network-informed interpretable machine learning

in Pathogen and Host Biology of Tuberculosis

Ethan Bustad
Edson Petry
Oliver Gu
Braden T. Griebel
Tige R. Rustad
David R. Sherman
Jason H. Yang
Shuyi Ma

Frontiers in Tuberculosis

doi 10.3389/ftubr.2025.1500899

3,692 views
3 citations

Original Research

Published on 30 Nov 2018

Elucidating the Role of Chromatin State and Transcription Factors on the Regulation of the Yeast Metabolic Cycle: A Multi-Omic Integrative Approach

in Epigenomics and Epigenetics

Víctor Sánchez-Gaya
Salvador Casaní-Galdón
Manuel Ugidos
Zheng Kuang
Jane Mellor
Ana Conesa
Sonia Tarazona

Frontiers in Genetics

doi 10.3389/fgene.2018.00578

7,653 views
17 citations

Original Research

Published on 14 Nov 2022

Anthocyanin-rich extract from black beans exerts anti-diabetic effects in rats through a multi-genomic mode of action in adipose tissue

in Nutrigenomics

Karla Damián-Medina
Dragan Milenkovic
Yolanda Salinas-Moreno
Karla Fabiola Corral-Jara
Luis Figueroa-Yáñez
Erika Marino-Marmolejo
Eugenia Lugo-Cervantes

Frontiers in Nutrition

doi 10.3389/fnut.2022.1019259

9,642 views
26 citations

Original Research

Published on 14 Sep 2021

Characterization of Organ-Specific Regulatory B Cells Using Single-Cell RNA Sequencing

in B Cell Biology

Si-Yu Yang
Jie Long
Meng-Xing Huang
Pan-Yue Luo
Zhen-Hua Bian
Ya-Fei Xu
Cheng-Bo Wang
Shu-Han Yang
Liang Li
Carlo Selmi

Frontiers in Immunology

doi 10.3389/fimmu.2021.711980

27,304 views
46 citations

Original Research

Published on 12 May 2020

α-Synuclein Negatively Regulates Nurr1 Expression Through NF-κB-Related Mechanism

in Molecular Signalling and Pathways

Congcong Jia
Hongqian Qi
Cheng Cheng
Xuefei Wu
Zhaofei Yang
Huaibin Cai
Sheng Chen
Weidong Le

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2020.00064

7,507 views
37 citations

Original Research

Published on 09 Jan 2026

Integrative single-cell atlas unveils heterogeneity and prognostic value of cancer-associated fibroblasts in gastric cancer

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Ziyu Jiang
Xiaomei Zhuang
Junkui Guo
Minyi Zhu
Chunhong Hong
Chunhui Sun
Kaiming Wu
Haofan Yin
Cuncan Deng
Ping Jiang

Frontiers in Oncology

doi 10.3389/fonc.2025.1559489

1,609 views
2 citations

Articles

Transmission of stimulus-induced epigenetic changes through cell division is coupled to continuous transcription factor activity

Patient Stratification of Clear Cell Renal Cell Carcinoma Using the Global Transcription Factor Activity Landscape Derived From RNA-Seq Data

MDM2 Binding Protein Induces the Resistance of Hepatocellular Carcinoma Cells to Molecular Targeting Agents via Enhancing the Transcription Factor Activity of the Pregnane X Receptor

Mechanistic insights and molecular therapy for neuroendocrine prostate cancer

Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension

Role of post-translational modifications of Sp1 in cancer: state of the art

Transcription Factor Control of Lymphatic Quiescence and Maturation of Lymphatic Neovessels in Development and Physiology

Identification of hub genes regulating the cell activity and function of adipose-derived stem cells under oxygen-glucose deprivation

A joint transcriptional regulatory network and protein activity inference analysis identifies clinically associated master regulators for biliary atresia

Transcriptome analysis of classical blood cells reveals downregulation of pro-inflammatory genes in the classical monocytes of long COVID patients

Predicting fitness in Mycobacterium tuberculosis with transcriptional regulatory network-informed interpretable machine learning

Elucidating the Role of Chromatin State and Transcription Factors on the Regulation of the Yeast Metabolic Cycle: A Multi-Omic Integrative Approach

Anthocyanin-rich extract from black beans exerts anti-diabetic effects in rats through a multi-genomic mode of action in adipose tissue

Characterization of Organ-Specific Regulatory B Cells Using Single-Cell RNA Sequencing

α-Synuclein Negatively Regulates Nurr1 Expression Through NF-κB-Related Mechanism

Integrative single-cell atlas unveils heterogeneity and prognostic value of cancer-associated fibroblasts in gastric cancer