Validation Methodology | List of Frontiers open access articles

Review

Published on 05 Nov 2025

Cross-generational mechanisms of maternal gut microbiota in modulating offspring autism spectrum disorder risk: from the gut-brain axis to translational challenges in precision interventions

in Neurocognitive Aging and Behavior

Dashuang Zhang
Min Zhou
Yudan Qiu
Hong Xu
Hanmin Liu
Yang Liu
Liang Xie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1642240

295 views

Original Research

Published on 05 Nov 2025

Investigation of the relationship between Fusobacterium nucleatum presence and inflammatory mediator expression in Kazakhstani patients with colorectal cancer

in Infectious Agents and Disease

Gulmira Kulmambetova
Botakoz Kurentay
Alua Gusmaulemova
Dina Bayanbek
Meiram Mamlin
Saule Khamzina
Sanzhar Shalekenov
Arman Kozhakhmetov

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1699745

329 views

Original Research

Published on 05 Nov 2025

Synergistic benefits of melatonin and therapeutic exercise as a unified strategy for managing stroke and doxorubicin-induced cardiotoxicity

in Experimental Therapeutics

Sookyoung Park
Zeeshan Ahmad Khan
Yunkyung Hong
Jinhee Shin
Tserentogtokh Lkhagvasuren
Seunghoon Lee
Yonggeun Hong

Frontiers in Neurology

doi 10.3389/fneur.2025.1567263

130 views

Original Research

Published on 05 Nov 2025

Effects of eculizumab and rituximab on visual function, motor function and social quality in patients with NMOSD: a comparative study

in Multiple Sclerosis and Neuroimmunology

Yihan Liu
Li Meng
Jiyuan Li
Xiao Wang
Xiaoman Zhang
Xiangzeng Kong
Yongzhi Zhang

Frontiers in Neurology

doi 10.3389/fneur.2025.1698950

251 views

Review

Published on 05 Nov 2025

Mylabris: a review of its biological characteristics, chemical composition, pharmacological, toxicology, pharmacokinetics, and marketed drugs

in Ethnopharmacology

Qingqing Cai
Jing Yan
Xinghong Li
Lihua He
Shan Xie
Yaxin Yang
Hongwei Wu
Fangbo Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652857

311 views

Original Research

Published on 05 Nov 2025

Beyond the positive glow: how school climate inadvertently challenges mental health by modifying the relationship between BMI and depression in adolescents

in Health Psychology

Ling Jiang
Qianyun He
Chaonan Chen

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1663969

329 views

Original Research

Published on 05 Nov 2025

Early prediction of sepsis-induced coagulopathy in the ICU using interpretable machine learning: a multi-center retrospective cohort study

in Intensive Care Medicine and Anesthesiology

Tao Sha
Hao Jiang
Lei Feng

Frontiers in Medicine

doi 10.3389/fmed.2025.1681621

355 views

Original Research

Published on 05 Nov 2025

ParaDeep: sequence-based deep learning for residue-level paratope prediction using chain-aware BiLSTM-CNN models

in Protein Bioinformatics

Piyachat Udomwong
Thanathat Pamonsupornwichit
Kanchanok Kodchakorn
Chatchai Tayapiwatana

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1684042

309 views

Case Report

Published on 05 Nov 2025

Case Report: Effective use of eculizumab in treating recurrent atypical HUS following renal transplantation triggered by SARS-CoV-2 infection

in Nephrology

Zhe Yang
Dongdong Chen
Xiaoyu Xu
Xiaoqing Yang
Wenzhi Du
Minrui Zhang
Xianduo Li
Jianning Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1515988

330 views

Perspective

Published on 05 Nov 2025

How the ASCENT model can help optimize exposure therapies for Autistic clients

in Autism

Amara Brook

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1569882

107 views

Original Research

Published on 05 Nov 2025

Variations in phenolic acid metabolites among Forsythia suspensa populations in response to environmental heterogeneity

in Plant Metabolism and Chemodiversity

Shanshan Zhou
Zhengsen Li
Qingyu Wang
Tianyu Cao
Danyang Li
Kailu Li
Jinlan Ji

Frontiers in Plant Science

doi 10.3389/fpls.2025.1683181

179 views

Original Research

Published on 05 Nov 2025

Serum proteomics and machine learning identify PSMD11 as a prognostic biomarker in severe fever with thrombocytopenia syndrome

in Viral Immunology

Chenxi Zhao
Ziruo Ge
Ranran Wang
Yanli Xu
Tingyu Zhang
Zhouling Jiang
Lu Liu
Ling Lin
Zhihai Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693946

386 views

Original Research

Published on 05 Nov 2025

Exploring 4 years of HIV pre-exposure prophylaxis as a statutory health insurance benefit in Germany—a longitudinal claims data analysis

in Infectious Diseases: Epidemiology and Prevention

Sandra Schmischke
Christian Kollan
Ursula Marschall
Daniel Schmidt

Frontiers in Public Health

doi 10.3389/fpubh.2025.1586736

173 views

Review

Published on 05 Nov 2025

Recent advances in Bletilla striata polysaccharide research: extraction methodologies, structural elucidation, pharmacological mechanisms, structure–activity relationships, and therapeutic delivery applications

in Ethnopharmacology

Bo Wang
Chaomeng Wu
Yingjuan Ma
Xiaofen Liu
Lijun Tao
Xuebing Zhou
Limin Jia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1688676

238 views

Original Research

Published on 05 Nov 2025

Bioinformatics insights into TMPO-AS1–let-7b-5p–ESPL1/E2F8 regulatory axis in breast cancer

in Cancer Cell Biology

Rajeev Nema
Prerna Vats
Aditi Singh
Jaya Thilakan
Swagata Brahmachari
Pallavi Kulkarni
Bhavika Baweja
Chainsee Saini
Sudhir K. Goel
Neha Arya

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1635862

569 views

Review

Published on 05 Nov 2025

Engineered cellulose hydrogels: multifunctional platforms for innovative stomatological therapies and precision medicine

in Biomaterials and Bio-Inspired Materials

Junyang Zhang
Rui Zhao
Xiyue Zhang
Fanqiao Dong
Yikun Zhang
Di Liu
Shuyu Meng
Ai Wang
Siyu Liu

Frontiers in Materials

doi 10.3389/fmats.2025.1647024

166 views

Articles

Cross-generational mechanisms of maternal gut microbiota in modulating offspring autism spectrum disorder risk: from the gut-brain axis to translational challenges in precision interventions

Investigation of the relationship between Fusobacterium nucleatum presence and inflammatory mediator expression in Kazakhstani patients with colorectal cancer

Synergistic benefits of melatonin and therapeutic exercise as a unified strategy for managing stroke and doxorubicin-induced cardiotoxicity

Effects of eculizumab and rituximab on visual function, motor function and social quality in patients with NMOSD: a comparative study

Mylabris: a review of its biological characteristics, chemical composition, pharmacological, toxicology, pharmacokinetics, and marketed drugs

Beyond the positive glow: how school climate inadvertently challenges mental health by modifying the relationship between BMI and depression in adolescents

Early prediction of sepsis-induced coagulopathy in the ICU using interpretable machine learning: a multi-center retrospective cohort study

ParaDeep: sequence-based deep learning for residue-level paratope prediction using chain-aware BiLSTM-CNN models

Case Report: Effective use of eculizumab in treating recurrent atypical HUS following renal transplantation triggered by SARS-CoV-2 infection

How the ASCENT model can help optimize exposure therapies for Autistic clients

Variations in phenolic acid metabolites among Forsythia suspensa populations in response to environmental heterogeneity

Serum proteomics and machine learning identify PSMD11 as a prognostic biomarker in severe fever with thrombocytopenia syndrome

Exploring 4 years of HIV pre-exposure prophylaxis as a statutory health insurance benefit in Germany—a longitudinal claims data analysis

Recent advances in Bletilla striata polysaccharide research: extraction methodologies, structural elucidation, pharmacological mechanisms, structure–activity relationships, and therapeutic delivery applications

Bioinformatics insights into TMPO-AS1–let-7b-5p–ESPL1/E2F8 regulatory axis in breast cancer

Engineered cellulose hydrogels: multifunctional platforms for innovative stomatological therapies and precision medicine

Exploring 4 years of HIV pre-exposure prophylaxis as a statutory health insurance benefit in Germany—a longitudinal claims data analysis