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CASE REPORT article

Front. Neurol.
Sec. Experimental Therapeutics
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1356662
This article is part of the Research Topic Review of Hyperbaric Therapy & Hyperbaric Oxygen Therapy in the Treatment of Neurological Disorders According to Dose of Pressure and Hyperoxia View all 12 articles

Case report: dementia sensitivity to altitude changes and effective treatment with hyperbaric air and glutathione precursors

Provisionally accepted
  • University of North Dakota, Grand Forks, United States

The final, formatted version of the article will be published soon.

    A 78-year-old male experienced waxing and waning of dementia symptoms with changes in altitude as he traveled from his home in the Rocky Mountains to lower elevations and back. To replicate the improvement in his symptoms with travel to lower elevations (higher pressure) the patient was treated with a near identical repressurization in a hyperbaric chamber using compressed air. With four one-hour treatments at 1.3 ATA and concurrent administration of lowdose oral glutathione amino acid precursors he recovered speech and improved activities of daily living. Regional broadcast media documented the novel recovery. Nosocomial COVID19 and withdrawal of sustaining hyperbaric therapy led to patient demise seven months after initiation of treatment. It is theorized that hyperbaric air therapy stimulated mitochondrial biochemical and physical changes that led to the clinical improvement.

    Keywords: Hyperbaric, Glutathione, pre-cursors, altitude, Wellness, pandemic, Dementia

    Received: 15 Dec 2023; Accepted: 10 May 2024.

    Copyright: © 2024 Fogarty. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Edward F. Fogarty, University of North Dakota, Grand Forks, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.