ORIGINAL RESEARCH article
Front. Aging Neurosci.
Sec. Neurocognitive Aging and Behavior
Volume 17 - 2025 | doi: 10.3389/fnagi.2025.1554901
This article is part of the Research TopicFrom Vulnerability to Vigor: Innovative Approaches in Frailty and Healthy AgingView all 7 articles
A trajectory study of postoperative frailty and cognitive function in elderly spinal surgery patients:A cohort study in China
Provisionally accepted
- 1Second Affiliated Hospital, Xuzhou Medical University, Xuzhou, China
- 2Chongqing General Hospital, Chongqing, Chongqing, China
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Objective To explore the developmental trajectory of postoperative frailty and cognitive function in elderly spinal surgery patients and the predictive relationship between the two. Methods A total of 266 elderly individuals were selected as the study subjects, and their debilitation and cognitive functions were tracked and investigated at T1 (at the time of discharge from the hospital), T2 (at 3 months postoperatively), and T3 (at 6 months postoperatively), and the data were analyzed using cross-lagged model and latent variable growth model. Results The latent variable growth model showed a decreasing trend in frailty (S=-0.197, P=0.013) and an increasing trend in postoperative cognitive function (S=0.124, P=0.002) from T1 to T3 in elderly spinal surgery patients; at the initial level, frailty was negatively correlated with cognitive function (r=-0.452, P<0.001), and initial levels of frailty negatively predicted the self development rate (β=-0.516, P<0.001), the initial level of frailty negatively predicted the development rate of postoperative cognitive function (β=-0.321, P=0.003), and the initial level of postoperative cognitive function positively predicted the development rate of frailty (β=0.192, P=0.031). Conclusion Elderly spinal surgery patients showed a decreasing trend of postoperative frailty and an increasing trend of postoperative cognitive function, frailty and postoperative cognitive function at the initial level had a mutual predictive effect, the initial level of frailty was able to negatively predict the rate of development of their own and postoperative cognitive function, and the initial level of postoperative cognitive function was able to positively predict the rate of development of frailty.
Keywords: Elderly spinal surgery, debilitation, Cognitive Function, Latent variable growth model, Cross-lag model, Nursing Care
Received: 03 Jan 2025; Accepted: 22 Oct 2025.
Copyright: © 2025 Li, Deng, Peng, Song, Shan, Wang and Jin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Chunyan Jin, 15062100130@163.com
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