Frontiers in Aging Neuroscience

Original Research

Accepted on 24 Apr 2025

Mirodenafil Improves Cognitive Function by Reducing Microglial Activation and Blood-Brain Barrier Permeability in ApoE4 KI Mice

in Alzheimer's Disease and Related Dementias

Yejin Park
Subin Moon
Harry Jung
Songyi Park
Ju Won Kim
Dan-Gyeong Song
Yong-Ho In
Sang Won Han
Jong-Hee Sohn
Chan Hee Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579411

Review

Published on 24 Apr 2025

Neuroprotective effects of electroacupuncture in ischemic stroke: from mechanisms to clinical implications

in Neuroinflammation and Neuropathy

Jinxi Zhu
Xinyi Ge
Yulong Cao
Renjie Xiao
Xiao Deng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562925

Review

Accepted on 23 Apr 2025

Iron Responsive Elements (IREs)-mRNA Regulate Alzheimer's Amyloid Precursor Protein (APP) Translation through Iron Sensing

in Alzheimer's Disease and Related Dementias

Mateen A. Khan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1483913

Original Research

Accepted on 23 Apr 2025

Blood biomarker as surrogate endpoint in Alzheimer's disease research

in Alzheimer's Disease and Related Dementias

Guogen Shan
Hui Li
Yahui Zhang
Guoqiao Wang
Charles Bernick

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1576373

Original Research

Accepted on 23 Apr 2025

Predicting Brain Age for Veterans with Traumatic Brain Injuries and Healthy Controls: An Exploratory Analysis

in Neurocognitive Aging and Behavior

John Philip Coetzee
Xiaojian Kang
victoria Liou-Johnson
Innes Luttenbacher
Srija Seenivasan
Elika Eshghi
Daya Grewal
Siddji Shah
Frank Hillary
Emily L Dennis

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1472207

Systematic Review

Published on 23 Apr 2025

Neural correlates of subjective cognitive decline in Alzheimer’s disease: a systematic review of structural and functional brain changes for early diagnosis and intervention

in Alzheimer's Disease and Related Dementias

Giulia Marafioti
Laura Culicetto
Desirèe Latella
Angela Marra
Angelo Quartarone
Viviana Lo Buono

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1549134

308 views

Original Research

Published on 23 Apr 2025

Machine learning models based on location-radiomics enable the accurate prediction of early neurological function deterioration for acute stroke in elderly patients

in Neurocognitive Aging and Behavior

Xiaoming Fu
Chuanyang Zhang
Hongjie Huang
Changcheng Li
Miaomiao Li
XiaoRan Li
Zhijun Gao
Mingyang Peng
Hui Xu
Wenli Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1582687

279 views

Original Research

Published on 23 Apr 2025

# Language processing characteristics in normal pressure hydrocephalus: insights from eye-tracking analysis of incorrect responses

in Neurocognitive Aging and Behavior

Ji-Yeong Kim
Jiho Lee
Nayeon Kim
Ki-Su Park
Janghyeok Yoon
Kyunghun Kang
Ji-Wan Ha

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1527962

367 views

Original Research

Published on 23 Apr 2025

The synergistic extract of Zophobas atratus and Tenebrio molitor regulates neuroplasticity and oxidative stress in a scopolamine-induced cognitive impairment model

in Cellular and Molecular Mechanisms of Brain-aging

Ngoc Buu Tran
Haesung Lee
Myoung-Geun Ji
Long Ngo Hoang
Sook-Jeong Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1566621

338 views

Review

Published on 23 Apr 2025

The role of quantitative EEG biomarkers in Alzheimer’s disease and mild cognitive impairment: applications and insights

in Alzheimer's Disease and Related Dementias

Yue Yuan
Yang Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522552

343 views

Original Research

Accepted on 22 Apr 2025

Stage-specific Functional Networks Associated with Cognitive Impairment in Parkinson's Disease: A Pilot fNIRS Study

in Neurocognitive Aging and Behavior

Jiarui Zhao
Yulai Gong
Zhenfang Lin
Jie Yang
Jiahuan Zou
Xia He
Yongshen He

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562203

Original Research

Accepted on 22 Apr 2025

Obesity Paradox in Cognitive Function: A Longitudinal Study of BMI and Cognitive Impairment in Elderly Chinese Population

in Neurocognitive Aging and Behavior

Jing Chen
Jun Zhang
Hao Wang
Hong liang Zhu
Jia lin Fu
Chuan wei Li
Qing rong Zhang
Xing zhi Xia
He Ma
Jun jun Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1543501

Brief Research Report

Accepted on 22 Apr 2025

Effectiveness of an exercise and nutrition intervention for older adults with mild cognitive impairment: an open-label double-arm clinical trial

in Neurocognitive Aging and Behavior

Moeko Noguchi-Shinohara
Kunihiko Yokoyama
Junji Komatsu
Kazumi Masuda
Mitsunobu Kouno
Mitsuhiro Yoshita
Kenjiro Ono

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1581400

Original Research

Accepted on 22 Apr 2025

Evaluation of Functional Capacity and Risk of Depression in Older Patients with Cancer as part of the Comprehensive Geriatric Assessment

in Neurocognitive Aging and Behavior

Wiesław Fidecki
Katarzyna Przylepa
Marek Wytrzyszczewski
Mariusz Wysokiński

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1595336

Original Research

Accepted on 22 Apr 2025

Internet Use, Physical Activity, and Cognitive Function in Chinese Older Adults: A Cross-Lagged Panel Analysis

in Neurocognitive Aging and Behavior

Jinfu Wang
Na Zhang
Chenxin Huang
Qinmei Wu
Jin Tong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579874

Study Protocol

Accepted on 22 Apr 2025

Impact of Impaired Intrinsic Capacity on Postoperative Frailty in Elderly Patients Undergoing Colorectal Surgery: Study Protocol for A Single-Center, Prospective, Cohort Study

in Neurocognitive Aging and Behavior

Jirun Wang
Shaoqi Tian
Lei Zhang
Jia Liu
Yuefang Liu
Lei Zhu
Peipei Shan
Ping Zhao
Yang Zhao
Youzhuang Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1523642