Frontiers in Aging Neuroscience

Review

Published on 02 Sep 2025

Associations between peripheral nerve stimulation and cognitive performance: insights from healthy individuals and various disease pathologies

in Neurocognitive Aging and Behavior

Xing Liu
Chenyi Yang
Xinyi Wang
Zixuan Wang
Huihui Liao
Huan Liu
Miao Zhang
Lin Zhang
Haiyun Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1518198

262 views

Original Research

Accepted on 01 Sep 2025

MFN2-A Multifaceted Guardian Against Parkinson's Pathophysiology: Mitochondria, Ferroptosis, Inflammation and Oxidative Stress

in Parkinson’s Disease and Aging-related Movement Disorders

Yan Cheng
Hongjiang Zhai
Yong Liu
Yun-Zhou Yang
Bo Fang
Mingxiang Song
Xiuqin Wang
Ping Zhong

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611958

Review

Accepted on 01 Sep 2025

STING-mediated Neuroinflammation: A Therapeutic Target in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Haoqin Zhang
Ziyang He
Can Yin
Shiyi Yang
Jianqiao Li
Hong Lin
Guishan Hu
Anguo Wu
Dalian Qin
Guangqiang Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1659216

Original Research

Accepted on 01 Sep 2025

Aerobic exercise and gut flora: a key link to improved cognitive impairment in mice with Parkinson's disease

in Parkinson’s Disease and Aging-related Movement Disorders

WenPeng Shan
ShiLei Yan
YuanYuan Guo
HuaKe Yang
JingChun Wang
Xiang Jie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630003

109 views

Original Research

Published on 01 Sep 2025

Dual improvement of cognitive function and auditory ability in elderly patients with hearing impairment by transcranial direct current stimulation-assisted auditory rehabilitation training

in Neurocognitive Aging and Behavior

Ying Zhou
Haolun Han
Xiaoli Zhang
Yiyan Zhang
Wenbo Duan
Liyun Su
Baowei Li
Zhezhe Sun
Lei Wang
Gang Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1591496

402 views

Mini Review

Published on 01 Sep 2025

The estrogen–brain interface in neuroinflammation: a multidimensional mechanistic insight

in Neuroinflammation and Neuropathy

Jie Lu
Tie-Jun Xian
Cheng-Jun Li
Yang Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671552

301 views

Brief Research Report

Accepted on 29 Aug 2025

Beyond Traditional Proxies: the Contribution of Leisure to Cognitive Reserve and Dementia

in Neurocognitive Aging and Behavior

Silvia Ottaviani
Luca Tagliafico
Stefania Peruzzo
Marta Ponzano
Alessio Signori
Alessio Nencioni
Fiammetta Monacelli

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600798

204 views

Review

Accepted on 29 Aug 2025

Biological determinants of blood-based biomarker levels in Alzheimer's Disease: Role of nutrition, inflammation, and metabolic factors

in Alzheimer's Disease and Related Dementias

Aparna Inamdar
Mahesh Palled
Savita Umarani
Chittipolu Manasa
B M Gurupadayya
Parashuram bugadannavar
Preeti Salve
priyanka patil
Himanshu Sharma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1614962

260 views

Original Research

Accepted on 29 Aug 2025

Empathy in Mild Cognitive Impairment: A Preliminary Clinical Comparative Study in Southern Switzerland Using the Interpersonal Reactivity Index (IRI) and the Story-Based Empathy Task (SET)

in Neurocognitive Aging and Behavior

Lisa Arnaud
Lucia Morellini
Laura Rege-Colet
Alberto Pagnamenta
Eleonora Fontana
Marianna Lissi
Rosalba Morese
Leonardo Sacco

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1661172

203 views

Methods

Accepted on 29 Aug 2025

Current Application Status of Non-Invasive Brain Stimulation Techniques in Alzheimer's Disease: A Bibliometric Analysis

in Alzheimer's Disease and Related Dementias

Shan Cong
Meng Wang
Long Yan
Li Sun
Bowen Zheng
Jinying Xie
Yulin Qian
Tao Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1585885

179 views

Original Research

Accepted on 29 Aug 2025

Association Between Cardiovascular Disease Risk, Regional Brain Age Gap, and Cognition in Healthy Adults

in Neurocognitive Aging and Behavior

Sriya Pallapothu
Roger D Newman-Norlund
Nicholas Riccardi
Leonardo Bonilha
Julius Fridriksson
Chris Rorden

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611847

153 views

Original Research

Published on 29 Aug 2025

Abnormal sleep blood pressure patterns are associated with the diffusion tensor imaging along the perivascular space index in cognitively impaired individuals

in Alzheimer's Disease and Related Dementias

Mariateresa Buongiorno
Gonzalo Sánchez-Benavides
Giovanni Caruana
Andrea Elias-Mas
Cristina Artero
Natalia Cullell
Pilar Delgado
Darly Milena Giraldo
Clara Marzal-Espí
Oriol Grau-Rivera

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1578270

651 views

Original Research

Published on 29 Aug 2025

Systemic inflammation versus clinical demographics: patient age surpasses the platelet-to-lymphocyte ratio in differentiating secondary trigeminal neuralgia

in Neuroinflammation and Neuropathy

Zihao Zhang
Qingpei Hao
Tao Wang
Shijun Peng
Xin Chang
Yuepeng Wang
Jia Ouyang
Ruen Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1658854

332 views

Mini Review

Published on 29 Aug 2025

Emerging biomarkers of postoperative delirium at the intersection of neuroinflammation and neurodegeneration

in Neuroinflammation and Neuropathy

Kun Leng
Mervyn Maze
Odmara L. Barreto Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632947

392 views

Mini Review

Published on 29 Aug 2025

Influence of biological sex on neuroinflammatory dynamics in the aging brain

in Neuroinflammation and Neuropathy

Ludmila Müller
Svetlana Di Benedetto
Viktor Müller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1670175

372 views

Original Research

Published on 29 Aug 2025

Association between shift work and brain age gap: a neuroimaging study using MRI-based brain age prediction algorithms

in Neurocognitive Aging and Behavior

Youjin Kim
Joon Yul Choi
Evgeny Petrovskiy
Wanhyung Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1650497

465 views