ORIGINAL RESEARCH article
Front. Aging Neurosci.
Sec. Neurocognitive Aging and Behavior
Volume 17 - 2025 | doi: 10.3389/fnagi.2025.1574275
The correlation between muscle strength, inhibitory function, and cognitive function in older adults with cognitive impairment: Evidence from resting-state electroencephalography
Provisionally accepted
- 1East China University of Political Science and Law, Shanghai, China
- 2Shanghai University of Sport, Shanghai, Shanghai Municipality, China
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Objective: This study explored the associations among muscle strength, inhibitory control, and cognitive function in older adults with cognitive impairment, focusing on related EEG changes. Methods: Among 247 adults aged 70 and above, 120 with cognitive impairment were included. Assessments included the Montreal Cognitive Assessment (MoCA), Stroop task, grip strength, and resting-state EEG. Results: Inhibitory control was significantly related to cognitive function: accuracy in congruent (r = 0.599, p < 0.001) and incongruent (r = 0.474, p < 0.001) conditions correlated positively with MoCA scores, while response times in both conditions showed negative correlations (r = -0.475 and -0.354, respectively, p < 0.001). EEG alpha1 (C3, P3, F7), alpha2 (P3, F8), and beta1 (P3, F7) power were significantly associated with both cognitive and inhibitory performance. Muscle strength was significantly positively correlated with specific EEG indicators, particularly alpha1 power at C4 (r = 0.212, p < 0.05), O2 (r = 0.204, p < 0.05), F8 (r = 0.225, p < 0.05), and T6 (r = 0.206, p < 0.05), as well as alpha2 power at C3 (r = 0.216, p < 0.05), P3 (r = 0.222, p < 0.05), P4 (r = 0.268, p < 0.001), F8 (r = 0.284, p < 0.001), and T5 (r = 0.218, p < 0.05).Conclusion: Muscle strength may support cognitive and inhibitory function by influencing specific EEG activities. These findings highlight the neurophysiological links among muscle strength, cognition, and brain activity, offering potential biomarkers for early detection and intervention in cognitive decline.
Keywords: inhibitory function, Cognitive Function, Muscle Strength, EEG, Older adult
Received: 10 Feb 2025; Accepted: 02 Jun 2025.
Copyright: © 2025 Hu and WANG. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xing WANG, Shanghai University of Sport, Shanghai, 200072, Shanghai Municipality, China
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