Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 10 Dec 2018

Prediction of Autopsy Verified Neuropathological Change of Alzheimer’s Disease Using Machine Learning and MRI

in Alzheimer's Disease and Related Dementias

Alexander Kautzky
Rene Seiger
Andreas Hahn
Peter Fischer
Wolfgang Krampla
Siegfried Kasper
Gabor G. Kovacs
Rupert Lanzenberger

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00406

7,756 views
39 citations

Original Research

Published on 29 Nov 2018

Uncovering Biologically Coherent Peripheral Signatures of Health and Risk for Alzheimer’s Disease in the Aging Brain

in Alzheimer's Disease and Related Dementias

Brandalyn C. Riedel
Madelaine Daianu
Greg Ver Steeg
Adam Mezher
Lauren E. Salminen
Aram Galstyan
Paul M. Thompson
Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00390

9,672 views
30 citations

Original Research

Published on 28 Nov 2018

Blood Markers in Healthy-Aged Nonagenarians: A Combination of High Telomere Length and Low Amyloidβ Are Strongly Associated With Healthy Aging in the Oldest Old

in Alzheimer's Disease and Related Dementias

Gorka Fernández-Eulate
Ainhoa Alberro
Maider Muñoz-Culla
Miren Zulaica
Mónica Zufiría
Myriam Barandiarán
Igone Etxeberria
José Javier Yanguas
Maria Mercedes Gallardo
Nora Soberón

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00380

4,832 views
3 citations

Review

Published on 27 Nov 2018

The Emerging Role of Altered Cerebellar Synaptic Processing in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Eriola Hoxha
Pellegrino Lippiello
Fabio Zurlo
Ilaria Balbo
Rita Santamaria
Filippo Tempia
Maria Concetta Miniaci

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00396

11,758 views
56 citations

Review

Published on 23 Nov 2018

TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism

in Alzheimer's Disease and Related Dementias

Honghua Zheng
Baoying Cheng
Yanfang Li
Xin Li
Xiaofen Chen
Yun-wu Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00395

24,815 views
79 citations

Original Research

Published on 22 Nov 2018

A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology

in Alzheimer's Disease and Related Dementias

Stephen L. P. Lippi
Meghann L. Smith
Jane M. Flinn

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00382

15,218 views
31 citations

Original Research

Published on 20 Nov 2018

Levels of Cortisol in CSF Are Associated With SNAP-25 and Tau Pathology but Not Amyloid-β

in Alzheimer's Disease and Related Dementias

Qing Wang
Wenjun Zhou
Jie Zhang
The Alzheimer’s Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00383

4,370 views
12 citations

Mini Review

Published on 14 Nov 2018

Blood-Based Kinase Assessments in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Jacques Hugon
François Mouton-Liger
Emmanuel Cognat
Julien Dumurgier
Claire Paquet

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00338

7,140 views
14 citations

Review

Published on 13 Nov 2018

The Early Events That Initiate β-Amyloid Aggregation in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Xingyu Zhang
Zhihui Fu
Lanxia Meng
Mingyang He
Zhentao Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00359

19,723 views
120 citations

Original Research

Published on 09 Nov 2018

Early Detection of Alzheimer’s Disease Using Non-invasive Near-Infrared Spectroscopy

in Alzheimer's Disease and Related Dementias

Rihui Li
Guoxing Rui
Wei Chen
Sheng Li
Paul E. Schulz
Yingchun Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00366

20,996 views
96 citations

Systematic Review

Published on 09 Nov 2018

25-Hydroxyvitamin D Levels and the Risk of Dementia and Alzheimer's Disease: A Dose–Response Meta-Analysis

in Alzheimer's Disease and Related Dementias

Hanze Chen
Weishuang Xue
Jinwei Li
Kailei Fu
Han Shi
Beidi Zhang
Weiyu Teng
Li Tian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00368

5,875 views
23 citations

Original Research

Published on 06 Nov 2018

Heme Oxygenase-1 and Brain Oxysterols Metabolism Are Linked to Egr-1 Expression in Aged Mice Cortex, but Not in Hippocampus

in Alzheimer's Disease and Related Dementias

Paolo Rosa
Chiara Zerbinati
Alessio Crestini
Anna-Maria Canudas
Giuseppe Ragona
Annamaria Confaloni
Luigi Iuliano
Antonella Calogero

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00363

4,504 views
14 citations

Original Research

Published on 02 Nov 2018

Anti-inflammatory Effects of Homotaurine in Patients With Amnestic Mild Cognitive Impairment

in Alzheimer's Disease and Related Dementias

Paola Bossù
Francesca Salani
Antonio Ciaramella
Eleonora Sacchinelli
Alessandra Mosca
Nerisa Banaj
Francesca Assogna
Maria Donata Orfei
Carlo Caltagirone
Walter Gianni

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00285

9,502 views
21 citations

Review

Published on 31 Oct 2018

Hyperhomocysteinemia as a Risk Factor for Vascular Contributions to Cognitive Impairment and Dementia

in Alzheimer's Disease and Related Dementias

Brittani R. Price
Donna M. Wilcock
Erica M. Weekman

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00350

16,143 views
116 citations

Original Research

Published on 30 Oct 2018

Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes

in Alzheimer's Disease and Related Dementias

Ana Espinosa
Begoña Hernández-Olasagarre
Sonia Moreno-Grau
Luca Kleineidam
Stefanie Heilmann-Heimbach
Isabel Hernández
Steffen Wolfsgruber
Holger Wagner
Maitée Rosende-Roca
Ana Mauleón

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00340

7,820 views
13 citations

Review

Published on 23 Oct 2018

Phyto-Therapeutic and Nanomedicinal Approaches to Cure Alzheimer’s Disease: Present Status and Future Opportunities

in Alzheimer's Disease and Related Dementias

Muhammad Ovais
Nashmia Zia
Irshad Ahmad
Ali Talha Khalil
Abida Raza
Muhammad Ayaz
Abdul Sadiq
Farhat Ullah
Zabta Khan Shinwari

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00284

20,376 views
132 citations

Review

Published on 19 Oct 2018

Corroboration of a Major Role for Herpes Simplex Virus Type 1 in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Ruth F. Itzhaki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00324

137,232 views
217 citations

Original Research

Published on 15 Oct 2018

Complementary and Alternative Medicine for Idiopathic Parkinson’s Disease: An Evidence-Based Clinical Practice Guideline

in Alzheimer's Disease and Related Dementias

Ki-Ho Cho
Tae-Hun Kim
Seungwon Kwon
Woo-Sang Jung
Sang-Kwan Moon
Chang-Nam Ko
Seung-Yeon Cho
Chan-Yong Jeon
Sang-Ho Lee
Tae Young Choi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00323

12,415 views
13 citations

Correction

Published on 12 Oct 2018

Corrigendum: Evaluation of Metformin on Cognitive Improvement in Patients With Non-dementia Vascular Cognitive Impairment and Abnormal Glucose Metabolism

in Alzheimer's Disease and Related Dementias

Yufeng Lin
Kaiyuan Wang
Chunchao Ma
Xuesong Wang
Zhongying Gong
Rui Zhang
Dawei Zang
Yan Cheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00322

2,784 views
11 citations

Systematic Review

Published on 11 Oct 2018

Changes in Cerebrospinal Fluid Tau and β-Amyloid Levels in Diabetic and Prediabetic Patients: A Meta-Analysis

in Alzheimer's Disease and Related Dementias

Yanhui Lu
Xinjun Jiang
Shuling Liu
Mingzi Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00271

5,441 views
32 citations

Review

Published on 09 Oct 2018

Chlamydia pneumoniae: An Etiologic Agent for Late-Onset Dementia

in Alzheimer's Disease and Related Dementias

Brian J. Balin
Christine J. Hammond
Christopher Scott Little
Susan T. Hingley
Zein Al-Atrache
Denah M. Appelt
Judith A. Whittum-Hudson
Alan P. Hudson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00302

11,845 views
77 citations

Review

Published on 09 Oct 2018

Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Aarti Mishra
Roberta D. Brinton

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00312

14,440 views
66 citations

Perspective

Published on 08 Oct 2018

Predict Disease Progression With Reaction Rate Equation Modeling of Multimodal MRI and PET

in Alzheimer's Disease and Related Dementias

Li Su
Yujing Huang
Yi Wang
James Rowe
John O’Brien

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00306

3,148 views
2 citations

Review

Published on 08 Oct 2018

Clinical PET Imaging of Microglial Activation: Implications for Microglial Therapeutics in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Zhiwei Shen
Xinjie Bao
Renzhi Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00314

12,635 views
71 citations

2,200 articles

articles

Prediction of Autopsy Verified Neuropathological Change of Alzheimer’s Disease Using Machine Learning and MRI

Uncovering Biologically Coherent Peripheral Signatures of Health and Risk for Alzheimer’s Disease in the Aging Brain

Blood Markers in Healthy-Aged Nonagenarians: A Combination of High Telomere Length and Low Amyloidβ Are Strongly Associated With Healthy Aging in the Oldest Old

The Emerging Role of Altered Cerebellar Synaptic Processing in Alzheimer’s Disease

TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism

A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology

Levels of Cortisol in CSF Are Associated With SNAP-25 and Tau Pathology but Not Amyloid-β

Blood-Based Kinase Assessments in Alzheimer’s Disease

The Early Events That Initiate β-Amyloid Aggregation in Alzheimer’s Disease

Early Detection of Alzheimer’s Disease Using Non-invasive Near-Infrared Spectroscopy

25-Hydroxyvitamin D Levels and the Risk of Dementia and Alzheimer's Disease: A Dose–Response Meta-Analysis

Heme Oxygenase-1 and Brain Oxysterols Metabolism Are Linked to Egr-1 Expression in Aged Mice Cortex, but Not in Hippocampus

Anti-inflammatory Effects of Homotaurine in Patients With Amnestic Mild Cognitive Impairment

Hyperhomocysteinemia as a Risk Factor for Vascular Contributions to Cognitive Impairment and Dementia

Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes

Phyto-Therapeutic and Nanomedicinal Approaches to Cure Alzheimer’s Disease: Present Status and Future Opportunities

Corroboration of a Major Role for Herpes Simplex Virus Type 1 in Alzheimer’s Disease

Complementary and Alternative Medicine for Idiopathic Parkinson’s Disease: An Evidence-Based Clinical Practice Guideline

Corrigendum: Evaluation of Metformin on Cognitive Improvement in Patients With Non-dementia Vascular Cognitive Impairment and Abnormal Glucose Metabolism

Changes in Cerebrospinal Fluid Tau and β-Amyloid Levels in Diabetic and Prediabetic Patients: A Meta-Analysis

Chlamydia pneumoniae: An Etiologic Agent for Late-Onset Dementia

Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer’s Disease

Predict Disease Progression With Reaction Rate Equation Modeling of Multimodal MRI and PET

Clinical PET Imaging of Microglial Activation: Implications for Microglial Therapeutics in Alzheimer’s Disease