Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 31 Jul 2018

The Aβ Containing Brain Extracts Having Different Effects in Alzheimer’s Disease Transgenic Caenorhabditis elegans and Mice

in Alzheimer's Disease and Related Dementias

Yufang Yang
Mo Wang
Ping Yang
Zishan Wang
Li Huang
Jing Xu
Wei Wang
Mei Yu
Liping Bu
Jian Fei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00208

6,811 views
3 citations

Clinical Trial

Published on 27 Jul 2018

Evaluation of Metformin on Cognitive Improvement in Patients With Non-dementia Vascular Cognitive Impairment and Abnormal Glucose Metabolism

in Alzheimer's Disease and Related Dementias

Yufeng Lin
Kaiyuan Wang
Chunchao Ma
Xuesong Wang
Zhongying Gong
Rui Zhang
Dawei Zang
Yan Cheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00227

18,599 views
73 citations

Original Research

Published on 24 Jul 2018

Inhibition of Phosphodiesterase-4 Reverses Aβ-Induced Memory Impairment by Regulation of HPA Axis Related cAMP Signaling

in Alzheimer's Disease and Related Dementias

Ying Xu
Naping Zhu
Wen Xu
Han Ye
Kaiping Liu
Feiyan Wu
Meixi Zhang
Yun Ding
Chong Zhang
Hanting Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00204

6,751 views
39 citations

Review

Published on 24 Jul 2018

Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer’s Disease?

in Alzheimer's Disease and Related Dementias

Tamas Fulop
Jacek M. Witkowski
Karine Bourgade
Abdelouahed Khalil
Echarki Zerif
Anis Larbi
Katsuiku Hirokawa
Graham Pawelec
Christian Bocti
Guy Lacombe

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00224

29,613 views
177 citations

Methods

Published on 19 Jul 2018

In Vivo Imaging of Microglia With Multiphoton Microscopy

in Alzheimer's Disease and Related Dementias

Carmen Hierro-Bujalance
Brian J. Bacskai
Monica Garcia-Alloza

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00218

25,955 views
38 citations

Original Research

Published on 18 Jul 2018

Dissociation of Tau Deposits and Brain Atrophy in Early Alzheimer’s Disease: A Combined Positron Emission Tomography/Magnetic Resonance Imaging Study

in Alzheimer's Disease and Related Dementias

Yoko Shigemoto
Daichi Sone
Etsuko Imabayashi
Norihide Maikusa
Nobuyuki Okamura
Shozo Furumoto
Yukitsuka Kudo
Masayo Ogawa
Harumasa Takano
Yuma Yokoi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00223

4,892 views
16 citations

Correction

Published on 17 Jul 2018

Corrigendum: Novel Prehospital Prediction Model of Large Vessel Occlusion Using Artificial Neural Network

in Alzheimer's Disease and Related Dementias

Zhicai Chen
Ruiting Zhang
Feizhou Xu
Xiaoxian Gong
Feina Shi
Meixia Zhang
Min Lou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00222

2,329 views
2 citations

Original Research

Published on 16 Jul 2018

Vitamin K Deficiency Induced by Warfarin Is Associated With Cognitive and Behavioral Perturbations, and Alterations in Brain Sphingolipids in Rats

in Alzheimer's Disease and Related Dementias

Sahar Tamadon-Nejad
Bouchra Ouliass
Joseph Rochford
Guylaine Ferland

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00213

10,473 views
43 citations

Original Research

Published on 16 Jul 2018

Fasudil in Combination With Bone Marrow Stromal Cells (BMSCs) Attenuates Alzheimer’s Disease-Related Changes Through the Regulation of the Peripheral Immune System

in Alzheimer's Disease and Related Dementias

Jiezhong Yu
Yuqing Yan
Qingfang Gu
Gajendra Kumar
Hongqiang Yu
Yijin Zhao
Chunyun Liu
Ye Gao
Zhi Chai
Jasleen Chumber

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00216

5,285 views
16 citations

Original Research

Published on 12 Jul 2018

Predicting Aging of Brain Metabolic Topography Using Variational Autoencoder

in Alzheimer's Disease and Related Dementias

Hongyoon Choi
Hyejin Kang
Dong Soo Lee
The Alzheimer's Disease Neuroimaging Initiative

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00212

6,879 views
31 citations

Perspective

Published on 12 Jul 2018

It’s Never Too Early or Too Late—End the Epidemic of Alzheimer’s by Preventing or Reversing Causation From Pre-birth to Death

in Alzheimer's Disease and Related Dementias

Clement L. Trempe
Thomas J. Lewis

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00205

8,744 views
10 citations

Mini Review

Published on 09 Jul 2018

TREM2-Dependent Effects on Microglia in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Yingyue Zhou
Tyler K. Ulland
Marco Colonna

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00202

29,187 views
78 citations

Original Research

Published on 05 Jul 2018

Long-Term DL-3-n-Butylphthalide Treatment Alleviates Cognitive Impairment Correlate With Improving Synaptic Plasticity in SAMP8 Mice

in Alzheimer's Disease and Related Dementias

Chaonan Lv
Qinying Ma
Bing Han
Jing Li
Yuan Geng
Xiaoman Zhang
Mingwei Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00200

4,678 views
26 citations

Original Research

Published on 03 Jul 2018

EEG Characteristics of Dementia With Lewy Bodies, Alzheimer’s Disease and Mixed Pathology

in Alzheimer's Disease and Related Dementias

Jessica J. van der Zande
Alida A. Gouw
Inger van Steenoven
Philip Scheltens
Cornelis Jan Stam
Afina W. Lemstra

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00190

26,492 views
78 citations

Original Research

Published on 26 Jun 2018

Sex-Based Differences in Gut Microbiota Composition in Response to Tuna Oil and Algae Oil Supplementation in a D-galactose-Induced Aging Mouse Model

in Alzheimer's Disease and Related Dementias

Hongyan Zhang
Zhaoyang Wang
Yanyan Li
Jiaojiao Han
Chenxi Cui
Chenyang Lu
Jun Zhou
Lingzhi Cheong
Ye Li
Tingting Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00187

7,622 views
28 citations

Review

Published on 22 Jun 2018

Potential Utility of Retinal Imaging for Alzheimer’s Disease: A Review

in Alzheimer's Disease and Related Dementias

Huan Liao
Zhuoting Zhu
Ying Peng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00188

17,863 views
60 citations

Review

Published on 21 Jun 2018

Metabolic and Vascular Imaging Biomarkers in Down Syndrome Provide Unique Insights Into Brain Aging and Alzheimer Disease Pathogenesis

in Alzheimer's Disease and Related Dementias

Elizabeth Head
David K. Powell
Frederick A. Schmitt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00191

6,860 views
22 citations

Original Research

Published on 18 Jun 2018

The Relation Between Brain Amyloid Deposition, Cortical Atrophy, and Plasma Biomarkers in Amnesic Mild Cognitive Impairment and Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Ling-Yun Fan
Kai-Yuan Tzen
Ya-Fang Chen
Ta-Fu Chen
Ya-Mei Lai
Ruoh-Fang Yen
Ya-Yao Huang
Chyng-Yann Shiue
Shieh-Yueh Yang
Ming-Jang Chiu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00175

10,386 views
56 citations

Mini Review

Published on 14 Jun 2018

APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction

in Alzheimer's Disease and Related Dementias

Jason A. Brandon
Brandon C. Farmer
Holden C. Williams
Lance A. Johnson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00180

12,712 views
67 citations

Original Research

Published on 12 Jun 2018

Sex Differences in Healthspan Predict Lifespan in the 3xTg-AD Mouse Model of Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Alice E. Kane
Sooyoun Shin
Aimee A. Wong
Emre Fertan
Natalia S. Faustova
Susan E. Howlett
Richard E. Brown

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00172

10,304 views
62 citations

Original Research

Published on 08 Jun 2018

Lower Expression of Ndfip1 Is Associated With Alzheimer Disease Pathogenesis Through Decreasing DMT1 Degradation and Increasing Iron Influx

in Alzheimer's Disease and Related Dementias

Juan Tian
Wei Zheng
Xin-Lu Li
Yuan-Hong Cui
Zhan-You Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00165

5,563 views
20 citations

Original Research

Published on 07 Jun 2018

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology

in Alzheimer's Disease and Related Dementias

Matthias Brendel
Behrooz H. Yousefi
Tanja Blume
Michael Herz
Carola Focke
Maximilian Deussing
Finn Peters
Simon Lindner
Barbara von Ungern-Sternberg
Alexander Drzezga

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00174

7,468 views
23 citations

Original Research

Published on 07 Jun 2018

Using CT Data to Improve the Quantitative Analysis of 18F-FBB PET Neuroimages

in Alzheimer's Disease and Related Dementias

Fermín Segovia
Raquel Sánchez-Vañó
Juan M. Górriz
Javier Ramírez
Pablo Sopena-Novales
Nathalie Testart Dardel
Antonio Rodríguez-Fernández
Manuel Gómez-Río

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00158

3,609 views
5 citations

Original Research

Published on 05 Jun 2018

Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice

in Alzheimer's Disease and Related Dementias

Wenjuan Yang
Keyan Zhou
Yue Zhou
Yuqian An
Tingting Hu
Jing Lu
Shichao Huang
Gang Pei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00169

7,087 views
44 citations

2,201 articles

articles

The Aβ Containing Brain Extracts Having Different Effects in Alzheimer’s Disease Transgenic Caenorhabditis elegans and Mice

Evaluation of Metformin on Cognitive Improvement in Patients With Non-dementia Vascular Cognitive Impairment and Abnormal Glucose Metabolism

Inhibition of Phosphodiesterase-4 Reverses Aβ-Induced Memory Impairment by Regulation of HPA Axis Related cAMP Signaling

Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer’s Disease?

In Vivo Imaging of Microglia With Multiphoton Microscopy

Dissociation of Tau Deposits and Brain Atrophy in Early Alzheimer’s Disease: A Combined Positron Emission Tomography/Magnetic Resonance Imaging Study

Corrigendum: Novel Prehospital Prediction Model of Large Vessel Occlusion Using Artificial Neural Network

Vitamin K Deficiency Induced by Warfarin Is Associated With Cognitive and Behavioral Perturbations, and Alterations in Brain Sphingolipids in Rats

Fasudil in Combination With Bone Marrow Stromal Cells (BMSCs) Attenuates Alzheimer’s Disease-Related Changes Through the Regulation of the Peripheral Immune System

Predicting Aging of Brain Metabolic Topography Using Variational Autoencoder

It’s Never Too Early or Too Late—End the Epidemic of Alzheimer’s by Preventing or Reversing Causation From Pre-birth to Death

TREM2-Dependent Effects on Microglia in Alzheimer’s Disease

Long-Term DL-3-n-Butylphthalide Treatment Alleviates Cognitive Impairment Correlate With Improving Synaptic Plasticity in SAMP8 Mice

EEG Characteristics of Dementia With Lewy Bodies, Alzheimer’s Disease and Mixed Pathology

Sex-Based Differences in Gut Microbiota Composition in Response to Tuna Oil and Algae Oil Supplementation in a D-galactose-Induced Aging Mouse Model

Potential Utility of Retinal Imaging for Alzheimer’s Disease: A Review

Metabolic and Vascular Imaging Biomarkers in Down Syndrome Provide Unique Insights Into Brain Aging and Alzheimer Disease Pathogenesis

The Relation Between Brain Amyloid Deposition, Cortical Atrophy, and Plasma Biomarkers in Amnesic Mild Cognitive Impairment and Alzheimer’s Disease

APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction

Sex Differences in Healthspan Predict Lifespan in the 3xTg-AD Mouse Model of Alzheimer’s Disease

Lower Expression of Ndfip1 Is Associated With Alzheimer Disease Pathogenesis Through Decreasing DMT1 Degradation and Increasing Iron Influx

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology

Using CT Data to Improve the Quantitative Analysis of 18F-FBB PET Neuroimages

Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice