Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 08 Jul 2024

Toward the development of a sporadic model of Alzheimer's disease: comparing pathologies between humanized APP and the familial J20 mouse models

in Alzheimer's Disease and Related Dementias

Peggy Rentsch
Kiruthika Ganesan
Alexander Langdon
Lyndsey M. Konen
Bryce Vissel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1421900

2,692 views
1 citation

Original Research

Published on 05 Jul 2024

Occlusion dysfunction and Alzheimer’s disease: Mendelian randomization study

in Alzheimer's Disease and Related Dementias

Qing Wang
Wenyu Zhen
Rui Hu
Zifei Wang
Yuqiang Sun
Wansu Sun
Chunxia Huang
Jianguang Xu
Hengguo Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1423322

3,201 views
3 citations

Original Research

Published on 04 Jul 2024

ACOT7, a candidate and novel serum biomarker of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Jintao Wang
Yong Feng
Yingni Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1345668

3,983 views

Mini Review

Published on 03 Jul 2024

The emerging role of brain neuroinflammatory responses in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Mandana Amelimojarad
Melika Amelimojarad
Xiaonan Cui

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1391517

4,513 views
16 citations

Original Research

Published on 03 Jul 2024

Time trends in Alzheimer’s disease mortality attributable to metabolic risks and smoking in China from 1990 to 2019: an age-period-cohort analysis

in Alzheimer's Disease and Related Dementias

Simeng Sun
Ting Zhang
Hao Yu
Ting Xia
Yunan Yao
Mengting Sun
Hongmei Liang
Qiaoyu Huang
Weiwei Wang
Huafeng Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1425577

6,110 views
7 citations

Original Research

Published on 28 Jun 2024

Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

in Alzheimer's Disease and Related Dementias

Allen L. Pan
Mickael Audrain
Emmy Sakakibara
Rajeev Joshi
Xiaodong Zhu
Qian Wang
Minghui Wang
Noam D. Beckmann
Eric E. Schadt
Sam Gandy

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1400447

3,535 views
3 citations

Original Research

Published on 26 Jun 2024

Integration of single-cell sequencing with machine learning and Mendelian randomization analysis identifies the NAP1L1 gene as a predictive biomarker for Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Runming Chen
Yujun Xie
Ze Chang
Wenyue Hu
Zhenyun Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1406160

5,227 views
1 citation

Original Research

Published on 26 Jun 2024

Predicting Alzheimer's disease CSF core biomarkers: a multimodal Machine Learning approach

in Alzheimer's Disease and Related Dementias

Anna Michela Gaeta
María Quijada-López
Ferran Barbé
Rafaela Vaca
Montse Pujol
Olga Minguez
Manuel Sánchez-de-la-Torre
Arrate Muñoz-Barrutia
Gerard Piñol-Ripoll

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1369545

5,610 views
10 citations

Original Research

Published on 21 Jun 2024

Changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age

in Alzheimer's Disease and Related Dementias

Melih Tarhan
Tim Hartl
Olena Shchyglo
Jens Colitti-Klausnitzer
Angela Kuhla
Tobias Maximilian Breuer
Denise Manahan-Vaughan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1373477

2,381 views

Original Research

Published on 21 Jun 2024

Enhancing predictive validity of motoric cognitive risk syndrome for incident dementia and all-cause mortality with handgrip strength: insights from a prospective cohort study

in Alzheimer's Disease and Related Dementias

Weimin Bai
Ruizhu Ma
Yanhui Yang
Juan Xu
Lijie Qin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1421656

2,145 views
2 citations

Original Research

Published on 19 Jun 2024

In-vivo neuronal dysfunction by Aβ and tau overlaps with brain-wide inflammatory mechanisms in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Lazaro M. Sanchez-Rodriguez
Ahmed F. Khan
Quadri Adewale
Gleb Bezgin
Joseph Therriault
Jaime Fernandez-Arias
Stijn Servaes
Nesrine Rahmouni
Cécile Tissot
Jenna Stevenson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1383163

4,559 views
5 citations

Editorial

Published on 18 Jun 2024

Editorial: Visualization and assessment of cerebral vasculature, cerebrospinal fluids, and the brain parenchyma in dementia and aging

in Alzheimer's Disease and Related Dementias

Jianpan Huang
Yachao Zhang
Lin Chen
Dengrong Jiang
Zixuan Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1443028

2,072 views

Original Research

Published on 18 Jun 2024

Long-lasting improvements in episodic memory among subjects with mild cognitive impairment who received transcranial direct current stimulation combined with cognitive treatment and telerehabilitation: a multicentre, randomized, active-controlled study

in Alzheimer's Disease and Related Dementias

Rosa Manenti
Francesca Baglio
Ilaria Pagnoni
Elena Gobbi
Elena Campana
Cristina Alaimo
Federica Rossetto
Sonia Di Tella
Chiara Pagliari
Andrea Geviti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1414593

3,925 views
4 citations

Original Research

Published on 17 Jun 2024

Generative AI unlocks PET insights: brain amyloid dynamics and quantification

in Alzheimer's Disease and Related Dementias

Matías Nicolás Bossa
Akshaya Ganesh Nakshathri
Abel Díaz Berenguer
Hichem Sahli

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1410844

3,205 views
2 citations

Review

Published on 13 Jun 2024

The alteration and role of glycoconjugates in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Yue Kang
Qian Zhang
Silu Xu
Yue Yu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1398641

3,817 views
2 citations

Original Research

Published on 12 Jun 2024

Dementia and metabolic syndrome: a bibliometric analysis

in Alzheimer's Disease and Related Dementias

Tao Peng
Yifan Yang
Jingying Ma
Peili Xu
Xinchun Xie
Nan Hu
Yongmei Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1400589

7,435 views
4 citations