Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Review

Published on 21 Sep 2018

Astrocyte Activation and the Calcineurin/NFAT Pathway in Cerebrovascular Disease

in Cellular and Molecular Mechanisms of Brain-aging

Susan D. Kraner
Christopher M. Norris

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00287

7,972 views
31 citations

Original Research

Published on 20 Sep 2018

Age Influences Microglial Activation After Cuprizone-Induced Demyelination

in Cellular and Molecular Mechanisms of Brain-aging

Barbara Klein
Heike Mrowetz
Conor Michael Barker
Simona Lange
Francisco J. Rivera
Ludwig Aigner

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00278

12,040 views
38 citations

Brief Research Report

Published on 07 Sep 2018

p58IPK Is an Endogenous Neuroprotectant for Retinal Ganglion Cells

in Cellular and Molecular Mechanisms of Brain-aging

Todd McLaughlin
Narayan Dhimal
Junhua Li
Joshua Jianxin Wang
Sarah Xin Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00267

4,908 views
15 citations

Original Research

Published on 22 Aug 2018

Both Basal and Acute Restraint Stress-Induced c-Fos Expression Is Influenced by Age in the Extended Amygdala and Brainstem Stress Centers in Male Rats

in Cellular and Molecular Mechanisms of Brain-aging

László Ákos Kovács
Josef Andreas Schiessl
Anna Elisabeth Nafz
Valér Csernus
Balázs Gaszner

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00248

10,388 views
30 citations

Original Research

Published on 21 Aug 2018

Expression Pattern of Myelin-Related Apolipoprotein D in Human Multiple Sclerosis Lesions

in Cellular and Molecular Mechanisms of Brain-aging

Ana Navarro
Beatriz Rioseras
Eva del Valle
Eva Martínez-Pinilla
Aurora Astudillo
Jorge Tolivia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00254

5,541 views
17 citations

Review

Published on 26 Jul 2018

Neuroimaging Biomarkers of mTOR Inhibition on Vascular and Metabolic Functions in Aging Brain and Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Jennifer Lee
Lucille M. Yanckello
David Ma
Jared D. Hoffman
Ishita Parikh
Scott Thalman
Bjoern Bauer
Anika M. S. Hartz
Fahmeed Hyder
Ai-Ling Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00225

18,663 views
21 citations

Original Research

Published on 26 Jul 2018

BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines

in Cellular and Molecular Mechanisms of Brain-aging

Tanja Blume
Severin Filser
Anna Jaworska
Jean-Francois Blain
Gerhard Koenig
Katrin Moschke
Stefan F. Lichtenthaler
Jochen Herms

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00229

6,142 views
34 citations

Mini Review

Published on 23 Jul 2018

MicroRNA Alterations in the Brain and Body Fluids of Humans and Animal Prion Disease Models: Current Status and Perspectives

in Cellular and Molecular Mechanisms of Brain-aging

Eirini Kanata
Katrin Thüne
Konstantinos Xanthopoulos
Isidre Ferrer
Dimitra Dafou
Inga Zerr
Theodoros Sklaviadis
Franc Llorens

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00220

6,289 views
24 citations

Mini Review

Published on 19 Jul 2018

In Vivo Two Photon Imaging of Astrocytic Structure and Function in Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Patricia Kelly
Eloise Hudry
Steven S. Hou
Brian J. Bacskai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00219

12,984 views
18 citations

Review

Published on 17 Jul 2018

Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis

in Cellular and Molecular Mechanisms of Brain-aging

Andrée-Anne Berthiaume
David A. Hartmann
Mark W. Majesky
Narayan R. Bhat
Andy Y. Shih

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00210

15,060 views
99 citations

Original Research

Published on 16 Jul 2018

Low Concentrations of Caffeine and Its Analogs Extend the Lifespan of Caenorhabditis elegans by Modulating IGF-1-Like Pathway

in Cellular and Molecular Mechanisms of Brain-aging

Xiaocui Du
Yun Guan
Qin Huang
Ming Lv
Xiaofang He
Liang Yan
Shuhei Hayashi
Chongye Fang
Xuanjun Wang
Jun Sheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00211

11,992 views
17 citations

Original Research

Published on 13 Jul 2018

Nicotine Modulates Cognitive Function in D-Galactose-Induced Senescence in Mice

in Cellular and Molecular Mechanisms of Brain-aging

Alireza Majdi
Saeed Sadigh-Eteghad
Mahnaz Talebi
Fereshteh Farajdokht
Marjan Erfani
Javad Mahmoudi
Albert Gjedde

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00194

7,276 views
30 citations

Review

Published on 09 Jul 2018

Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Pradoldej Sompol
Christopher M. Norris

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00199

13,674 views
78 citations

Original Research

Published on 29 Jun 2018

Screening for CCNF Mutations in a Chinese Amyotrophic Lateral Sclerosis Cohort

in Cellular and Molecular Mechanisms of Brain-aging

Danyang Tian
Jiao Li
Lu Tang
Nan Zhang
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00185

3,855 views
7 citations

Original Research

Published on 26 Jun 2018

Preventing P-gp Ubiquitination Lowers Aβ Brain Levels in an Alzheimer’s Disease Mouse Model

in Cellular and Molecular Mechanisms of Brain-aging

Anika M. S. Hartz
Yu Zhong
Andrew N. Shen
Erin L. Abner
Björn Bauer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00186

9,994 views
49 citations

General Commentary

Published on 25 Jun 2018

Commentary: Mild endoplasmic reticulum stress ameliorates lpopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization

in Cellular and Molecular Mechanisms of Brain-aging

Sachchida N. Rai
Walia Zahra
Hareram Birla
Saumitra S. Singh
Surya P. Singh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00192

3,255 views
22 citations

Original Research

Published on 08 Jun 2018

Leucine Carboxyl Methyltransferase Downregulation and Protein Phosphatase Methylesterase Upregulation Contribute Toward the Inhibition of Protein Phosphatase 2A by α-Synuclein

in Cellular and Molecular Mechanisms of Brain-aging

Hao Tian
Yongquan Lu
Jia Liu
Weijin Liu
Lingling Lu
Chunli Duan
Ge Gao
Hui Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00173

5,276 views
19 citations

Original Research

Published on 31 May 2018

Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age

in Cellular and Molecular Mechanisms of Brain-aging

Giulia Costa
Annalisa Pinna
Pier Francesca Porceddu
Maria Antonietta Casu
Anna Di Maio
Francesco Napolitano
Alessandro Usiello
Micaela Morelli

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00163

4,439 views
10 citations

Original Research

Published on 23 May 2018

Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex

in Cellular and Molecular Mechanisms of Brain-aging

Thomas E. Chan
Yael S. Grossman
Erik B. Bloss
William G. Janssen
Wendy Lou
Bruce S. McEwen
Dani Dumitriu
John H. Morrison

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00146

9,170 views
20 citations

Original Research

Published on 23 May 2018

DNA Methylation Profiling Reveals the Change of Inflammation-Associated ZC3H12D in Leukoaraiosis

in Cellular and Molecular Mechanisms of Brain-aging

Wen-Qing Huang
Ke-Hui Yi
Zhi Li
Han Wang
Ming-Li Li
Liang-Liang Cai
Hui-Nuan Lin
Qing Lin
Chi-Meng Tzeng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00143

7,110 views
16 citations

Original Research

Published on 18 May 2018

Streptozotocin Impairs Proliferation and Differentiation of Adult Hippocampal Neural Stem Cells in Vitro-Correlation With Alterations in the Expression of Proteins Associated With the Insulin System

in Cellular and Molecular Mechanisms of Brain-aging

Ping Sun
Gabriela Ortega
Yan Tan
Qian Hua
Peter F. Riederer
Jürgen Deckert
Angelika G. Schmitt-Böhrer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00145

9,084 views
28 citations

Review

Published on 15 May 2018

Regulation of MicroRNAs-Mediated Autophagic Flux: A New Regulatory Avenue for Neurodegenerative Diseases With Focus on Prion Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Syed Zahid Ali Shah
Deming Zhao
Tariq Hussain
Naveed Sabir
Lifeng Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00139

8,346 views
34 citations

Review

Published on 14 May 2018

Role of Ionizing Radiation in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Neel K. Sharma
Rupali Sharma
Deepali Mathur
Shashwat Sharad
Gillipsie Minhas
Kulsajan Bhatia
Akshay Anand
Sanchita P. Ghosh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00134

32,459 views
59 citations

Original Research

Published on 09 May 2018

Brain Distribution and Modulation of Neuronal Excitability by Indicaxanthin From Opuntia Ficus Indica Administered at Nutritionally-Relevant Amounts

in Cellular and Molecular Mechanisms of Brain-aging

Giuditta Gambino
Mario Allegra
Pierangelo Sardo
Alessandro Attanzio
Luisa Tesoriere
Maria A. Livrea
Giuseppe Ferraro
Fabio Carletti

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00133

6,725 views
33 citations

747 articles

articles

Astrocyte Activation and the Calcineurin/NFAT Pathway in Cerebrovascular Disease

Age Influences Microglial Activation After Cuprizone-Induced Demyelination

p58IPK Is an Endogenous Neuroprotectant for Retinal Ganglion Cells

Both Basal and Acute Restraint Stress-Induced c-Fos Expression Is Influenced by Age in the Extended Amygdala and Brainstem Stress Centers in Male Rats

Expression Pattern of Myelin-Related Apolipoprotein D in Human Multiple Sclerosis Lesions

Neuroimaging Biomarkers of mTOR Inhibition on Vascular and Metabolic Functions in Aging Brain and Alzheimer’s Disease

BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines

MicroRNA Alterations in the Brain and Body Fluids of Humans and Animal Prion Disease Models: Current Status and Perspectives

In Vivo Two Photon Imaging of Astrocytic Structure and Function in Alzheimer’s Disease

Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis

Low Concentrations of Caffeine and Its Analogs Extend the Lifespan of Caenorhabditis elegans by Modulating IGF-1-Like Pathway

Nicotine Modulates Cognitive Function in D-Galactose-Induced Senescence in Mice

Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases

Screening for CCNF Mutations in a Chinese Amyotrophic Lateral Sclerosis Cohort

Preventing P-gp Ubiquitination Lowers Aβ Brain Levels in an Alzheimer’s Disease Mouse Model

Commentary: Mild endoplasmic reticulum stress ameliorates lpopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization

Leucine Carboxyl Methyltransferase Downregulation and Protein Phosphatase Methylesterase Upregulation Contribute Toward the Inhibition of Protein Phosphatase 2A by α-Synuclein

Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age

Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex

DNA Methylation Profiling Reveals the Change of Inflammation-Associated ZC3H12D in Leukoaraiosis

Streptozotocin Impairs Proliferation and Differentiation of Adult Hippocampal Neural Stem Cells in Vitro-Correlation With Alterations in the Expression of Proteins Associated With the Insulin System

Regulation of MicroRNAs-Mediated Autophagic Flux: A New Regulatory Avenue for Neurodegenerative Diseases With Focus on Prion Diseases

Role of Ionizing Radiation in Neurodegenerative Diseases

Brain Distribution and Modulation of Neuronal Excitability by Indicaxanthin From Opuntia Ficus Indica Administered at Nutritionally-Relevant Amounts