Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 08 May 2018

Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging

in Cellular and Molecular Mechanisms of Brain-aging

David A. Loeffler
Andrea C. Klaver
Mary P. Coffey
Jan O. Aasly

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00130

5,337 views
15 citations

Review

Published on 27 Apr 2018

Mitochondria, Estrogen and Female Brain Aging

in Cellular and Molecular Mechanisms of Brain-aging

Imane Lejri
Amandine Grimm
Anne Eckert

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00124

44,500 views
112 citations

Review

Published on 25 Apr 2018

The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease

in Cellular and Molecular Mechanisms of Brain-aging

Holly M. Brothers
Maya L. Gosztyla
Stephen R. Robinson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00118

49,347 views
278 citations

Review

Published on 25 Apr 2018

Deciphering the Astrocyte Reaction in Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Beatriz G. Perez-Nievas
Alberto Serrano-Pozo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00114

39,148 views
263 citations

Original Research

Published on 24 Apr 2018

Expression of Cyclin-D1 in Astrocytes Varies During Aging

in Cellular and Molecular Mechanisms of Brain-aging

Brigitte Ciapa
Sylvie Granon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00104

5,514 views
8 citations

Original Research

Published on 24 Apr 2018

Sophora flavescens Aiton Decreases MPP+-Induced Mitochondrial Dysfunction in SH-SY5Y Cells

in Cellular and Molecular Mechanisms of Brain-aging

Hee-Young Kim
Hyongjun Jeon
Hyungwoo Kim
Sungtae Koo
Seungtae Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00119

11,513 views
29 citations

Original Research

Published on 12 Apr 2018

The rs696880 Polymorphism in the Nogo-A Receptor Gene (RTN4R) Is Associated With Susceptibility to Sporadic Amyotrophic Lateral Sclerosis in the Chinese Population

in Cellular and Molecular Mechanisms of Brain-aging

Lianping Xu
Jiao Li
Danyang Tian
Lu Chen
Lu Tang
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00108

3,728 views
8 citations

Review

Published on 26 Mar 2018

The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Hongfeng Zhang
Timothy Huang
Yujuan Hong
Weijie Yang
Xian Zhang
Hong Luo
Huaxi Xu
Xin Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00079

24,642 views
88 citations

Original Research

Published on 20 Mar 2018

TRPC1 Deletion Causes Striatal Neuronal Cell Apoptosis and Proteomic Alterations in Mice

in Cellular and Molecular Mechanisms of Brain-aging

Dian Wang
Haitao Yu
Benhong Xu
Hua Xu
Zaijun Zhang
Xiaohu Ren
Jianhui Yuan
Jianjun Liu
Yi Guo
Peter S. Spencer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00072

4,278 views
10 citations

Review

Published on 12 Mar 2018

The Aging of Iron Man

in Cellular and Molecular Mechanisms of Brain-aging

Azhaar Ashraf
Maryam Clark
Po-Wah So

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00065

28,306 views
146 citations

Original Research

Published on 02 Mar 2018

Crossmodal Connections of Primary Sensory Cortices Largely Vanish During Normal Aging

in Cellular and Molecular Mechanisms of Brain-aging

Julia U. Henschke
Frank W. Ohl
Eike Budinger

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00052

6,039 views
13 citations

Original Research

Published on 27 Feb 2018

Tetrathiomolybdate Treatment Leads to the Suppression of Inflammatory Responses through the TRAF6/NFκB Pathway in LPS-Stimulated BV-2 Microglia

in Cellular and Molecular Mechanisms of Brain-aging

Zhuo Wang
Ya-Hong Zhang
Chuang Guo
Hui-Ling Gao
Man-Li Zhong
Ting-Ting Huang
Na-Na Liu
Rui-Fang Guo
Tian Lan
Wei Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00009

8,572 views
30 citations

Original Research

Published on 27 Feb 2018

Urinary 8-oxo-7,8-dihydroguanosine as a Potential Biomarker of Aging

in Cellular and Molecular Mechanisms of Brain-aging

Wei Gan
Xin-Le Liu
Ting Yu
Yuan-Gao Zou
Ting-Ting Li
Shuang Wang
Jin Deng
Lan-Lan Wang
Jian-Ping Cai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00034

27,918 views
61 citations

Original Research

Published on 16 Feb 2018

Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice

in Cellular and Molecular Mechanisms of Brain-aging

Aurel Popa-Wagner
Raluca E. Sandu
Coman Cristin
Adriana Uzoni
Kevin A. Welle
Jennifer R. Hryhorenko
Sina Ghaemmaghami

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00032

6,062 views
23 citations

Original Research

Published on 15 Feb 2018

The Complement System Is Critical in Maintaining Retinal Integrity during Aging

in Cellular and Molecular Mechanisms of Brain-aging

Ryo Mukai
Yoko Okunuki
Deeba Husain
Clifford B. Kim
John D. Lambris
Kip M. Connor

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00015

9,440 views
53 citations

Original Research

Published on 15 Feb 2018

Long-Term Potentiation Enhances Neuronal Differentiation in the Chronic Hypoperfusion Model of Rats

in Cellular and Molecular Mechanisms of Brain-aging

Hayato Takeuchi
Masahiro Kameda
Takao Yasuhara
Tatsuya Sasaki
Atsuhiko Toyoshima
Jun Morimoto
Kyohei Kin
Mihoko Okazaki
Michiari Umakoshi
Ittetsu Kin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00029

4,823 views
7 citations

Mini Review

Published on 06 Feb 2018

Dissecting Endoplasmic Reticulum Unfolded Protein Response (UPRER) in Managing Clandestine Modus Operandi of Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Safikur Rahman
Ayyagari Archana
Arif Tasleem Jan
Rinki Minakshi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00030

9,454 views
32 citations

Original Research

Published on 06 Feb 2018

Plasma Exosomal miRNA-122-5p and miR-300-3p as Potential Markers for Transient Ischaemic Attack in Rats

in Cellular and Molecular Mechanisms of Brain-aging

Dong-Bin Li
Jing-Li Liu
Wei Wang
Xiu-Mei Luo
Xia Zhou
Jin-Pin Li
Xiao-Li Cao
Xiao-Hong Long
Jia-Gui Chen
Chao Qin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00024

9,612 views
65 citations

Original Research

Published on 30 Jan 2018

α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise

in Cellular and Molecular Mechanisms of Brain-aging

Simona Daniele
Deborah Pietrobono
Jonathan Fusi
Annalisa Lo Gerfo
Eugenio Cerri
Lucia Chico
Caterina Iofrida
Lucia Petrozzi
Filippo Baldacci
Chiara Giacomelli

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00017

5,865 views
23 citations

Original Research

Published on 08 Jan 2018

Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides

in Cellular and Molecular Mechanisms of Brain-aging

Shaobin Yang
Sònia Pascual-Guiral
Rebeca Ponce
Lydia Giménez-Llort
María A. Baltrons
Ottavio Arancio
Jose R. Palacio
Victoria M. Clos
Victor J. Yuste
Jose R. Bayascas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2017.00435

8,823 views
38 citations

Original Research

Published on 19 Dec 2017

Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson’s Disease through NF-κB/pAKT Signaling Pathways

in Cellular and Molecular Mechanisms of Brain-aging

Sachchida N. Rai
Hareram Birla
Saumitra S. Singh
Walia Zahra
Ravishankar R. Patil
Jyoti P. Jadhav
Mallikarjuna R. Gedda
Surya P. Singh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2017.00421

41,861 views
153 citations

Original Research

Published on 08 Dec 2017

Multi-Protection of DL0410 in Ameliorating Cognitive Defects in D-Galactose Induced Aging Mice

in Cellular and Molecular Mechanisms of Brain-aging

Wenwen Lian
Hao Jia
Lvjie Xu
Wei Zhou
De Kang
Ailin Liu
Guanhua Du

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2017.00409

8,128 views
27 citations

Original Research

Published on 08 Dec 2017

Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment

in Cellular and Molecular Mechanisms of Brain-aging

Lara Ianov
Matt De Both
Monica K. Chawla
Asha Rani
Andrew J. Kennedy
Ignazio Piras
Jeremy J. Day
Ashley Siniard
Ashok Kumar
J. David Sweatt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2017.00383

10,475 views
53 citations

Review

Published on 07 Dec 2017

Role of Sex Hormones on Brain Mitochondrial Function, with Special Reference to Aging and Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Pauline Gaignard
Philippe Liere
Patrice Thérond
Michael Schumacher
Abdelhamid Slama
Rachida Guennoun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2017.00406

19,751 views
114 citations

747 articles

articles

Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging

Mitochondria, Estrogen and Female Brain Aging

The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease

Deciphering the Astrocyte Reaction in Alzheimer’s Disease

Expression of Cyclin-D1 in Astrocytes Varies During Aging

Sophora flavescens Aiton Decreases MPP+-Induced Mitochondrial Dysfunction in SH-SY5Y Cells

The rs696880 Polymorphism in the Nogo-A Receptor Gene (RTN4R) Is Associated With Susceptibility to Sporadic Amyotrophic Lateral Sclerosis in the Chinese Population

The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases

TRPC1 Deletion Causes Striatal Neuronal Cell Apoptosis and Proteomic Alterations in Mice

The Aging of Iron Man

Crossmodal Connections of Primary Sensory Cortices Largely Vanish During Normal Aging

Tetrathiomolybdate Treatment Leads to the Suppression of Inflammatory Responses through the TRAF6/NFκB Pathway in LPS-Stimulated BV-2 Microglia

Urinary 8-oxo-7,8-dihydroguanosine as a Potential Biomarker of Aging

Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice

The Complement System Is Critical in Maintaining Retinal Integrity during Aging

Long-Term Potentiation Enhances Neuronal Differentiation in the Chronic Hypoperfusion Model of Rats

Dissecting Endoplasmic Reticulum Unfolded Protein Response (UPRER) in Managing Clandestine Modus Operandi of Alzheimer’s Disease

Plasma Exosomal miRNA-122-5p and miR-300-3p as Potential Markers for Transient Ischaemic Attack in Rats

α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise

Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides

Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson’s Disease through NF-κB/pAKT Signaling Pathways

Multi-Protection of DL0410 in Ameliorating Cognitive Defects in D-Galactose Induced Aging Mice

Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment

Role of Sex Hormones on Brain Mitochondrial Function, with Special Reference to Aging and Neurodegenerative Diseases