Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 29 Apr 2020

Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo

in Cellular and Molecular Mechanisms of Brain-aging

Amy R. Nelson
Meghana A. Sagare
Yaoming Wang
Kassandra Kisler
Zhen Zhao
Berislav V. Zlokovic

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00108

9,146 views
73 citations

Review

Published on 17 Apr 2020

Resveratrol Derivatives as Potential Treatments for Alzheimer’s and Parkinson’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Bruno Dutra Arbo
Corinne André-Miral
Raif Gregorio Nasre-Nasser
Lúcia Emanueli Schimith
Michele Goulart Santos
Dennis Costa-Silva
Ana Luiza Muccillo-Baisch
Mariana Appel Hort

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00103

25,579 views
114 citations

Original Research

Published on 15 Apr 2020

Hypertension and Pathogenic hAPP Independently Induce White Matter Astrocytosis and Cognitive Impairment in the Rat

in Cellular and Molecular Mechanisms of Brain-aging

Alexander Levit
Sonny Cheng
Olivia Hough
Qingfan Liu
Yuksel Agca
Cansu Agca
Vladimir Hachinski
Shawn N. Whitehead

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00082

3,540 views
7 citations

Review

Published on 14 Apr 2020

Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia

in Cellular and Molecular Mechanisms of Brain-aging

Maiko T. Uemura
Takakuni Maki
Masafumi Ihara
Virginia M. Y. Lee
John Q. Trojanowski

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00080

38,948 views
188 citations

Review

Published on 09 Apr 2020

Astroglia and Tau: New Perspectives

in Cellular and Molecular Mechanisms of Brain-aging

Gabor G. Kovacs

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00096

15,850 views
97 citations

Original Research

Published on 09 Apr 2020

Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss

in Cellular and Molecular Mechanisms of Brain-aging

Philine Marchetta
Dorit Möhrle
Philipp Eckert
Katrin Reimann
Steffen Wolter
Arianna Tolone
Isabelle Lang
Markus Wolters
Robert Feil
Jutta Engel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00083

7,064 views
11 citations

Brief Research Report

Published on 20 Mar 2020

Endogenous Apelin Is Protective Against Age-Associated Loss of Retinal Ganglion Cells in Mice

in Cellular and Molecular Mechanisms of Brain-aging

Yuki Ishimaru
Akihide Sumino
Fumiya Shibagaki
Akiko Yamamuro
Yasuhiro Yoshioka
Sadaaki Maeda

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00058

4,459 views
5 citations

Review

Published on 06 Mar 2020

Succination of Protein Thiols in Human Brain Aging

in Cellular and Molecular Mechanisms of Brain-aging

Mariona Jové
Irene Pradas
Natalia Mota-Martorell
Rosanna Cabré
Victoria Ayala
Isidre Ferrer
Reinald Pamplona

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00052

6,721 views
14 citations

Brief Research Report

Published on 28 Feb 2020

Impaired Fluid Intake, but Not Sodium Appetite, in Aged Rats Is Mediated by the Cyclooxygenase-Prostaglandin E2 Pathway

in Cellular and Molecular Mechanisms of Brain-aging

Denovan P. Begg
Andrew J. Sinclair
Richard S. Weisinger

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00019

2,952 views
5 citations

Original Research

Published on 11 Feb 2020

The Density of Perineuronal Nets Increases With Age in the Inferior Colliculus in the Fischer Brown Norway Rat

in Cellular and Molecular Mechanisms of Brain-aging

Amir M. Mafi
Lindsay N. Hofer
Matthew G. Russ
Jesse W. Young
Jeffrey G. Mellott

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00027

5,081 views
18 citations

Original Research

Published on 11 Feb 2020

The Interaction of EphA4 With PDGFRβ Regulates Proliferation and Neuronal Differentiation of Neural Progenitor Cells in vitro and Promotes Neurogenesis in vivo

in Cellular and Molecular Mechanisms of Brain-aging

Qingfa Chen
Hao Song
Chuanguo Liu
Jun Xu
Chuanfei Wei
Wei Wang
Fabin Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00007

6,037 views
18 citations

Review

Published on 07 Feb 2020

Microbial BMAA and the Pathway for Parkinson’s Disease Neurodegeneration

in Cellular and Molecular Mechanisms of Brain-aging

Daniela Nunes-Costa
João Duarte Magalhães
Maria G-Fernandes
Sandra Morais Cardoso
Nuno Empadinhas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00026

38,053 views
74 citations

Perspective

Published on 07 Feb 2020

Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals

in Cellular and Molecular Mechanisms of Brain-aging

Jesse R. Poganik
Yimon Aye

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00001

4,819 views
38 citations

Mini Review

Published on 28 Jan 2020

Differences Between Human and Murine Tau at the N-terminal End

in Cellular and Molecular Mechanisms of Brain-aging

Félix Hernández
Jesús Merchán-Rubira
Laura Vallés-Saiz
Alberto Rodríguez-Matellán
Jesús Avila

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2020.00011

15,700 views
49 citations

Original Research

Published on 22 Jan 2020

Effects of Intranasal Orexin-A (Hypocretin-1) Administration on Neuronal Activation, Neurochemistry, and Attention in Aged Rats

in Cellular and Molecular Mechanisms of Brain-aging

Coleman B. Calva
Habiba Fayyaz
Jim R. Fadel

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00362

11,360 views
21 citations

Original Research

Published on 15 Jan 2020

Aging Disrupts the Circadian Patterns of Protein Expression in the Murine Hippocampus

in Cellular and Molecular Mechanisms of Brain-aging

Paula Adler
Cheng-Kang Chiang
Janice Mayne
Zhibin Ning
Xu Zhang
Bo Xu
Hai-Ying Mary Cheng
Daniel Figeys

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00368

8,916 views
30 citations