Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 08 Sep 2014

Reciprocal modulation of Aβ42 aggregation by copper and homocysteine

in Cellular and Molecular Mechanisms of Brain-aging

Salla Keskitalo
Melinda Farkas
Michael Hanenberg
Anita Szodorai
Luka Kulic
Alexander Semmler
Michael Weller
Roger M. Nitsch
Michael Linnebank

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00237

8,250 views
10 citations

Review

Published on 01 Sep 2014

Synchronizing an aging brain: can entraining circadian clocks by food slow Alzheimer’s disease?

in Cellular and Molecular Mechanisms of Brain-aging

Brianne A. Kent

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00234

10,442 views
21 citations

Original Research

Published on 28 Aug 2014

Shorter Telomeres in Peripheral Blood Mononuclear Cells from Older Persons with Sarcopenia: Results from an Exploratory Study

in Cellular and Molecular Mechanisms of Brain-aging

Emanuele Marzetti
Maria Lorenzi
Manuela Antocicco
Stefano Bonassi
Michela Celi
Simona Mastropaolo
Silvana Settanni
Vanessa Valdiglesias
Francesco Landi
Roberto Bernabei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00233

10,269 views
61 citations

Original Research

Published on 25 Aug 2014

Deficiency of prion protein induces impaired autophagic flux in neurons

in Cellular and Molecular Mechanisms of Brain-aging

Hae-Young Shin
Jeong-Ho Park
Richard I. Carp
Eun-Kyoung Choi
Yong-Sun Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00207

11,068 views
12 citations

Original Research

Published on 25 Aug 2014

n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice

in Cellular and Molecular Mechanisms of Brain-aging

Debora Cutuli
Paola De Bartolo
Paola Caporali
Daniela Laricchiuta
Francesca Foti
Maurizio Ronci
Claudia Rossi
Cristina Neri
Gianfranco Spalletta
Carlo Caltagirone

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00220

13,680 views
105 citations

Original Research

Published on 19 Aug 2014

Aggresome–Autophagy Involvement in a Sarcopenic Patient with Rigid Spine Syndrome and a p.C150R Mutation in FHL1 Gene

in Cellular and Molecular Mechanisms of Brain-aging

Patrizia Sabatelli
Silvia Castagnaro
Francesca Tagliavini
Martina Chrisam
Francesca Sardone
Laurence Demay
Pascale Richard
Spartaco Santi
Nadir M. Maraldi
Luciano Merlini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00215

8,719 views
20 citations

Review

Published on 19 Aug 2014

Therapeutic and diagnostic challenges for frontotemporal dementia

in Cellular and Molecular Mechanisms of Brain-aging

Simon D’Alton
Jada Lewis

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00204

12,229 views
22 citations

Review

Published on 11 Aug 2014

The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle

in Cellular and Molecular Mechanisms of Brain-aging

Marta Gonzalez-Freire
Rafael de Cabo
Stephanie A. Studenski
Luigi Ferrucci

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00208

57,142 views
308 citations

Original Research

Published on 11 Aug 2014

SIRT2 enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via apoptotic pathway

in Cellular and Molecular Mechanisms of Brain-aging

Lei Liu
Anirudh Arun
Lakia Ellis
Carina Peritore
Gizem Donmez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00184

8,341 views
58 citations

Original Research

Published on 05 Aug 2014

Structure activity relationship of phenolic acid inhibitors of α-synuclein fibril formation and toxicity

in Cellular and Molecular Mechanisms of Brain-aging

Mustafa T. Ardah
Katerina E. Paleologou
Guohua Lv
Salema B. Abul Khair
Abdulla S. Kazim
Saeed T. Minhas
Taleb H. Al-Tel
Abdulmonem A. Al-Hayani
Mohammed E. Haque
David Eliezer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00197

26,283 views
114 citations

Original Research

Published on 04 Aug 2014

Subtype and Regional-Specific Neuroinflammation in Sporadic Creutzfeldt–Jakob Disease

in Cellular and Molecular Mechanisms of Brain-aging

Franc Llorens
Irene López-González
Katrin Thüne
Margarita Carmona
Saima Zafar
Olivier Andréoletti
Inga Zerr
Isidre Ferrer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00198

9,382 views
66 citations

Original Research

Published on 01 Aug 2014

The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress

in Cellular and Molecular Mechanisms of Brain-aging

Yun-Ching Chang
Wei-Chao Chang
Kuo-Hsuan Hung
Der-Ming Yang
Yung-Hsin Cheng
Yi-Wen Liao
Lin-Chung Woung
Ching-Yao Tsai
Chih-Chien Hsu
Tai-Chi Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00191

16,353 views
76 citations

Review

Published on 23 Jul 2014

The Potential for Transition Metal-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

in Cellular and Molecular Mechanisms of Brain-aging

David B. Lovejoy
Gilles J. Guillemin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00173

12,513 views
63 citations

Review

Published on 21 Jul 2014

β-secretase inhibitor; a promising novel therapeutic drug in Alzheimer’s disease

in Cellular and Molecular Mechanisms of Brain-aging

Kelly Willemijn Menting
Jurgen A. H. R. Claassen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00165

29,770 views
133 citations

Review

Published on 03 Jul 2014

Copper: from neurotransmission to neuroproteostasis

in Cellular and Molecular Mechanisms of Brain-aging

Carlos M. Opazo
Mark A. Greenough
Ashley I. Bush

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00143

26,121 views
146 citations

Original Research

Published on 03 Jul 2014

Laminin α2 Chain-Deficiency is Associated with microRNA Deregulation in Skeletal Muscle and Plasma

in Cellular and Molecular Mechanisms of Brain-aging

Johan Holmberg
Azra Alajbegovic
Kinga Izabela Gawlik
Linda Elowsson
Madeleine Durbeej

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00155

6,400 views
26 citations

Review

Published on 25 Jun 2014

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

in Cellular and Molecular Mechanisms of Brain-aging

Sara M. Hancock
David I. Finkelstein
Paul A. Adlard

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00137

9,574 views
41 citations

Original Research

Published on 20 Jun 2014

Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury

in Cellular and Molecular Mechanisms of Brain-aging

George E. Barreto
Maria Santos-Galindo
Luis Miguel Garcia-Segura

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00132

10,667 views
66 citations

Original Research

Published on 19 Jun 2014

Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system

in Cellular and Molecular Mechanisms of Brain-aging

Josée Coulombe
Prasanna Gamage
Madison T. Gray
Mei Zhang
Matthew Y. Tang
John Woulfe
M. Jill Saffrey
Douglas A. Gray

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00129

10,456 views
37 citations

Original Research

Published on 16 Jun 2014

Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS

in Cellular and Molecular Mechanisms of Brain-aging

Megan W. Bourassa
Hilda H. Brown
David R. Borchelt
Stefan Vogt
Lisa M. Miller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00110

10,670 views
66 citations

Original Research

Published on 03 Jun 2014

SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin

in Cellular and Molecular Mechanisms of Brain-aging

Huiqiang Chen
Xianbao Liu
Wei Zhu
Han Chen
Xinyang Hu
Zhi Jiang
Yinchuan Xu
Lihan Wang
Yu Zhou
Panpan Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00103

16,080 views
112 citations

Review

Published on 22 May 2014

Degeneration of Neuromuscular Junction in Age and Dystrophy

in Cellular and Molecular Mechanisms of Brain-aging

Rüdiger Rudolf
Muzamil Majid Khan
Siegfried Labeit
Michael R. Deschenes

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00099

24,090 views
166 citations

Original Research

Published on 16 May 2014

Alzheimer’s disease causation by copper toxicity and treatment with zinc

in Cellular and Molecular Mechanisms of Brain-aging

George J. Brewer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00092

36,112 views
70 citations

Mini Review

Published on 14 May 2014

Resveratrol and Alzheimer’s disease: message in a bottle on red wine and cognition

in Cellular and Molecular Mechanisms of Brain-aging

Alberto Granzotto
Paolo Zatta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00095

40,023 views
98 citations

747 articles

articles

Reciprocal modulation of Aβ42 aggregation by copper and homocysteine

Synchronizing an aging brain: can entraining circadian clocks by food slow Alzheimer’s disease?

Shorter Telomeres in Peripheral Blood Mononuclear Cells from Older Persons with Sarcopenia: Results from an Exploratory Study

Deficiency of prion protein induces impaired autophagic flux in neurons

n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice

Aggresome–Autophagy Involvement in a Sarcopenic Patient with Rigid Spine Syndrome and a p.C150R Mutation in FHL1 Gene

Therapeutic and diagnostic challenges for frontotemporal dementia

The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle

SIRT2 enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via apoptotic pathway

Structure activity relationship of phenolic acid inhibitors of α-synuclein fibril formation and toxicity

Subtype and Regional-Specific Neuroinflammation in Sporadic Creutzfeldt–Jakob Disease

The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress

The Potential for Transition Metal-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

β-secretase inhibitor; a promising novel therapeutic drug in Alzheimer’s disease

Copper: from neurotransmission to neuroproteostasis

Laminin α2 Chain-Deficiency is Associated with microRNA Deregulation in Skeletal Muscle and Plasma

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury

Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system

Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS

SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin

Degeneration of Neuromuscular Junction in Age and Dystrophy

Alzheimer’s disease causation by copper toxicity and treatment with zinc

Resveratrol and Alzheimer’s disease: message in a bottle on red wine and cognition