Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 11 Aug 2014

SIRT2 enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via apoptotic pathway

in Cellular and Molecular Mechanisms of Brain-aging

Lei Liu
Anirudh Arun
Lakia Ellis
Carina Peritore
Gizem Donmez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00184

7,791 views
56 citations

Original Research

Published on 05 Aug 2014

Structure activity relationship of phenolic acid inhibitors of α-synuclein fibril formation and toxicity

in Cellular and Molecular Mechanisms of Brain-aging

Mustafa T. Ardah
Katerina E. Paleologou
Guohua Lv
Salema B. Abul Khair
Abdulla S. Kazim
Saeed T. Minhas
Taleb H. Al-Tel
Abdulmonem A. Al-Hayani
Mohammed E. Haque
David Eliezer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00197

24,518 views
111 citations

Original Research

Published on 04 Aug 2014

Subtype and Regional-Specific Neuroinflammation in Sporadic Creutzfeldt–Jakob Disease

in Cellular and Molecular Mechanisms of Brain-aging

Franc Llorens
Irene López-González
Katrin Thüne
Margarita Carmona
Saima Zafar
Olivier Andréoletti
Inga Zerr
Isidre Ferrer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00198

8,570 views
64 citations

Original Research

Published on 01 Aug 2014

The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress

in Cellular and Molecular Mechanisms of Brain-aging

Yun-Ching Chang
Wei-Chao Chang
Kuo-Hsuan Hung
Der-Ming Yang
Yung-Hsin Cheng
Yi-Wen Liao
Lin-Chung Woung
Ching-Yao Tsai
Chih-Chien Hsu
Tai-Chi Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00191

15,545 views
75 citations

Review

Published on 23 Jul 2014

The Potential for Transition Metal-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

in Cellular and Molecular Mechanisms of Brain-aging

David B. Lovejoy
Gilles J. Guillemin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00173

11,585 views
59 citations

Review

Published on 21 Jul 2014

β-secretase inhibitor; a promising novel therapeutic drug in Alzheimer’s disease

in Cellular and Molecular Mechanisms of Brain-aging

Kelly Willemijn Menting
Jurgen A. H. R. Claassen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00165

28,212 views
131 citations

Review

Published on 03 Jul 2014

Copper: from neurotransmission to neuroproteostasis

in Cellular and Molecular Mechanisms of Brain-aging

Carlos M. Opazo
Mark A. Greenough
Ashley I. Bush

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00143

23,952 views
136 citations

Original Research

Published on 03 Jul 2014

Laminin α2 Chain-Deficiency is Associated with microRNA Deregulation in Skeletal Muscle and Plasma

in Cellular and Molecular Mechanisms of Brain-aging

Johan Holmberg
Azra Alajbegovic
Kinga Izabela Gawlik
Linda Elowsson
Madeleine Durbeej

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00155

5,883 views
25 citations

Review

Published on 25 Jun 2014

Glia and zinc in ageing and Alzheimer’s disease: a mechanism for cognitive decline?

in Cellular and Molecular Mechanisms of Brain-aging

Sara M. Hancock
David I. Finkelstein
Paul A. Adlard

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00137

8,880 views
39 citations

Original Research

Published on 20 Jun 2014

Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury

in Cellular and Molecular Mechanisms of Brain-aging

George E. Barreto
Maria Santos-Galindo
Luis Miguel Garcia-Segura

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00132

9,997 views
63 citations

Original Research

Published on 19 Jun 2014

Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system

in Cellular and Molecular Mechanisms of Brain-aging

Josée Coulombe
Prasanna Gamage
Madison T. Gray
Mei Zhang
Matthew Y. Tang
John Woulfe
M. Jill Saffrey
Douglas A. Gray

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00129

9,468 views
36 citations

Original Research

Published on 16 Jun 2014

Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS

in Cellular and Molecular Mechanisms of Brain-aging

Megan W. Bourassa
Hilda H. Brown
David R. Borchelt
Stefan Vogt
Lisa M. Miller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00110

9,612 views
62 citations

Original Research

Published on 03 Jun 2014

SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin

in Cellular and Molecular Mechanisms of Brain-aging

Huiqiang Chen
Xianbao Liu
Wei Zhu
Han Chen
Xinyang Hu
Zhi Jiang
Yinchuan Xu
Lihan Wang
Yu Zhou
Panpan Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00103

14,630 views
106 citations

Review

Published on 22 May 2014

Degeneration of Neuromuscular Junction in Age and Dystrophy

in Cellular and Molecular Mechanisms of Brain-aging

Rüdiger Rudolf
Muzamil Majid Khan
Siegfried Labeit
Michael R. Deschenes

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00099

22,591 views
160 citations

Original Research

Published on 16 May 2014

Alzheimer’s disease causation by copper toxicity and treatment with zinc

in Cellular and Molecular Mechanisms of Brain-aging

George J. Brewer

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00092

34,162 views
63 citations

Mini Review

Published on 14 May 2014

Resveratrol and Alzheimer’s disease: message in a bottle on red wine and cognition

in Cellular and Molecular Mechanisms of Brain-aging

Alberto Granzotto
Paolo Zatta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2014.00095

38,483 views
95 citations