Your new experience awaits. Try the new design now and help us make it even better

SYSTEMATIC REVIEW article

Front. Digit. Health

Sec. Health Technology Implementation

Volume 7 - 2025 | doi: 10.3389/fdgth.2025.1560533

This article is part of the Research TopicDigital Health Innovations for Patient-Centered CareView all 27 articles

Electronic Patient-Reported Outcome Systems and Capabilities in Cancer Care: A Systematic Review

Provisionally accepted
Hosna  SalmaniHosna Salmani1Somayeh  NasiriSomayeh Nasiri1*Mahdi  AlemrajabiMahdi Alemrajabi2Maryam  AhmadiMaryam Ahmadi1
  • 1Iran University of Medical Sciences, Tehran, Iran
  • 2Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Tehran, Iran

The final, formatted version of the article will be published soon.

Background: Cancer care increasingly emphasizes patient-centred approaches, leading to the adoption of electronic patient-reported outcome (ePRO) systems for essential patient data collection. Our systematic review investigates the landscape of electronic patient-reported outcome systems and their capability in cancer care, focusing on their potential to enhance patient-centred solutions.We conducted a systematic review, encompassing studies on electronic patient-reported outcomes in cancer. We searched in Scopus, Web of Science, and PubMed using comprehensive Medical Subject Heading (MeSH) terms up to April 2024. Papers were categorized based on nine key aspects, including author, publication year, country/state, objective, participants, cancer type, system name, system capabilities, and type of platform. Eligible studies were appraised using a mixed-methods appraisal tool (MMAT) Results: Analysis of 85 studies indicated a diverse range of electronic Patient-Reported Outcome systems and platforms in cancer care, Notably, PRO-CTCAE and CHES were frequently cited for their roles in data collection and analysis. Moreover, web-based platforms were predominant, followed by mobile-based and computer-based systems. In addition, Symptom assessment and management emerged as significant capabilities in the utilization of these systems for oncology care.Our systematic review of electronic patient-reported outcome (ePRO) systems in cancer care focused on the capabilities of these systems for capturing patient data and improving cancer treatment outcomes. This study emphasized the potential of electronic systems to enhance patient-centred oncology practices and optimize cancer care delivery.

Keywords: electronic patient-reported outcome systems, ePRO, Cancer, patient-centred solutions, capability

Received: 06 Feb 2025; Accepted: 08 Jul 2025.

Copyright: © 2025 Salmani, Nasiri, Alemrajabi and Ahmadi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Somayeh Nasiri, Iran University of Medical Sciences, Tehran, Iran

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.