ORIGINAL RESEARCH article
Front. Digit. Health
Sec. Connected Health
Volume 7 - 2025 | doi: 10.3389/fdgth.2025.1612915
Heart Disease prediction with Feature Sensitized Interpretable Framework for Internet of Medical Sensors
Provisionally accepted- 1Balaji Institute of Modern Management (BIMM), Pune, Maharashtra, India
- 2Loyola College, Chennai, Chennai, Tamil Nadu, India
- 3School of Built Environment, Engineering & Computing, Leeds Beckett University, Leeds, United Kingdom
- 4Leeds Beckett University, Leeds, England, United Kingdom
- 5Symbiosis International University, Pune, Maharashtra, India
- 6Széchenyi István University, Gyor, Gyor-Moson-Sopron, Hungary
- 7The University of Manchester, Manchester, England, United Kingdom
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The central control system of the human body is the heart. The terms pertaining as the heart of the city or the heart of the computer is understood, for the solidity 1 Nallakaruppan et al. Running Title of heart as a part of human conversations. Challenging situations like cholesterol, high blood pressure, stress, obesity, lifestyle, smoking, and drinking challenge the functioning of the heart. The drastic increase in younger people dying of heart failure is the most undesirable and common situation in recent times. Postpandemic, this situation has become common among the age group of 25-40 years, due to the impact of medication and the post pandemic health practices. This enhances the need of the automatic interpretable framework, with feature analysis for the heart disease prediction. The proposed work provides a solution for this early heart failure situation by constantly monitoring the body's vitals through wearable and other Internet of Medical Things (IoMT) sensors and then integrating the data into the cloud. The next step entails extracting the data sets from the cloud to perform classification with the help of machine learning models such as SVM, Random Forest, Decision Tree, and Logistic Regression. The proposed work selects the Random Forest Classification model with the highest accuracy and F1-score compared to all other models with the value of 0.955, with k fold validation. Subsequently, it applies for explainability using LIME in local surrogates and SHAPELY in global surrogates. SHAPELY's decision plot describes classification behavior with the decision and other plots.
Keywords: XAI, Lime, Shapely, random forest, PDP, heart failure prediction, Heart disease
Received: 25 Apr 2025; Accepted: 11 Aug 2025.
Copyright: © 2025 Kailasanathan, Ezhilarasan, Selvarajan, Dhanaraj, Pamucar and Shankar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Shitharth Selvarajan, School of Built Environment, Engineering & Computing, Leeds Beckett University, Leeds, United Kingdom
Dragan Pamucar, Széchenyi István University, Gyor, 9026, Gyor-Moson-Sopron, Hungary
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