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ORIGINAL RESEARCH article

Front. Digit. Health

Sec. Health Informatics

Volume 7 - 2025 | doi: 10.3389/fdgth.2025.1678364

Profile-Aided Distillation Framework for Personalized Sleep Analysis with Compact Models Using LLM-Guided Synthetic Data

Provisionally accepted
  • 1South China University of Technology, Guangzhou, China
  • 2Jinan University, Guangzhou, China
  • 3The First Affiliated Hospital of Jinan University, Guangzhou, China

The final, formatted version of the article will be published soon.

Enabling personalized sleep analysis and interaction directly on edge devices is crucial for providing real-time health insights and tailored guidance, yet remains challenging due to data scarcity and computational constraints. In this study, we propose a novel framework for personalized sleep analysis on edge devices, addressing two critical obstacles: the scarcity of publicly available physiological datasets and the limited capacity of compact models. To mitigate data scarcity, we introduce a Physiologically-Constrained Adaptive Hierarchical Copula approach, which leverages large language model-guided optimization to synthesize diverse and realistic physiological data. To enhance the limited personalized inference capabilities of compact models, we develop a Profile-Aided distillation of expert inference with MoE LoRA, which integrates user-specific information to enhance the performance of edge-deployed models. This strategy enables efficient, individualized inference and decision-making, while overcoming the limitations inherent in standard LoRA fine-tuning. Extensive experiments on both public and in-house datasets demonstrate that our distilled models achieve performance on par with state-of-the-art LLMs, yet operate efficiently within the constraints of edge devices. Overall, this work presents a promising solution for enabling personalized sleep analysis and user interaction in resource-constrained environments.

Keywords: Personalized Sleep Analysis, large language model (LLM), model distillation, Data synthesis, Edge computation

Received: 02 Aug 2025; Accepted: 20 Oct 2025.

Copyright: © 2025 Zheng, Ai, Liu, Xing and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Huimin Zheng, 202210182130@mail.scut.edu.cn

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