TECHNOLOGY AND CODE article
Front. Genet.
Sec. Livestock Genomics
Volume 16 - 2025 | doi: 10.3389/fgene.2025.1573374
EnrichKit: A Multi-Omics Tool for Livestock Research
Provisionally accepted
- Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Florida, United States
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The increasing applications of omics technologies in livestock research highlights the need for tools capable of interpreting preliminary signals, such as mapping genomic coordinates to gene features and annotating gene lists for functional characteristics. These tools should effectively leverage various biological databases for comprehensive analysis. Additionally, the development of user-friendly interfaces is essential to broaden the accessibility and enable a wider range of users to contribute more effectively to the field of livestock genomics. EnrichKit provides friendly graphical user interface and superior efficiency in data management and computational analysis by integrating various public databases and statistical algorithms. Its functionalities are showcased through applications in DNA methylation analysis, gene coexpression network analysis, and differential gene expression analysis. The comparative analysis with existing tools underscores EnrichKit advantages in terms of species-specific geneset libraries and user accessibility. EnrichKit significantly advances the interpretation of omics studies in livestock genomics. Its tailored approach for species-specific analysis, combined with a comprehensive computational framework, positions it as a valuable tool for researchers. The potential of EnrichKit to transform livestock genomics research is evident, opening avenues for future enhancements and broader applications in the livestock omics research field.
Keywords: Software, Overrepresentation analysis, P-value Aggregation, RNA-Seq, WGBS-seq
Received: 08 Feb 2025; Accepted: 24 Apr 2025.
Copyright: © 2025 Peñagaricano and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Francisco Peñagaricano, Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, 32611, Florida, United States
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