Frontiers in Genetics

Original Research

Published on 18 Aug 2026

Comprehensive analysis of SYTL4 differential expression and clinical implications in DLBCL

in Cancer Genetics and Oncogenomics

Yue Li
Qiqi Zhou

Frontiers in Genetics

doi 10.3389/fgene.2026.1908683

205 views

Opinion

Published on 18 Aug 2026

Repositioning candidate gene approaches in the post-GWAS era: a clinical perspective from psychiatric pharmacogenetics

in Pharmacogenetics and Pharmacogenomics

Milica Pjevac
Jurij Bon
Vita Dolžan

Frontiers in Genetics

doi 10.3389/fgene.2026.1828563

584 views

Systematic Review

Published on 18 Aug 2026

Diagnostic accuracy of cell-free DNA-based non-invasive prenatal testing for fetal aneuploidies: a systematic review

in Human and Medical Genomics

Sharif Alhajlah

Frontiers in Genetics

doi 10.3389/fgene.2026.1886738

670 views

Original Research

Published on 18 Aug 2026

NLRP3 inflammasome pathway activation is associated with cardiac remodeling, gut microbiota dysbiosis, and dietary protein restriction in a rat heart failure model: an integrative exploratory analysis

in Human and Medical Genomics

Xiaopeng Li
Chen Yang
Mengmeng Nie
Yong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2026.1852819

247 views

Original Research

Accepted on 17 Aug 2026

Genotype-phenotypic correlation in a Chinese patient with isolated lissencephaly sequence caused by 17p13.3p13.2 chromosomal microdeletion

in Genetics of Common and Rare Diseases

Jiao Tong
Xu Chen
Tao Wang
Shan Ma
Yali Zhao
Dongdong Shi
Xin Wang
Dongmei Yan

Frontiers in Genetics

Case Report

Accepted on 17 Aug 2026

Presymptomatic Risdiplam in Preterm Monozygotic Twins with Co-occurring Spinal Muscular Atrophy and Tuberous Sclerosis Complex

in Genetics of Common and Rare Diseases

Xiaofang zhang
Yanjuan Wang
Si-Xiu Li
Ping Liu
Wenguang Hu

Frontiers in Genetics

Case Report

Accepted on 17 Aug 2026

A Rare De Novo Contiguous 15q11.1-q13.3 Duplication with Tetrasomy (CN=4) and Adjacent Trisomy (CN=3) Associated with Severe Global Developmental Delay, Autism Spectrum Disorder, and Subclinical Epileptiform Discharges: A Case Report and Literature Review

in Genetics of Common and Rare Diseases

Xinyu Zhou
HongYan Xie
Haoyan Yu
Zhiyuan Zhang
Yangfan Qi
Kai Jiang
Shungzhu Lin

Frontiers in Genetics

Original Research

Accepted on 17 Aug 2026

Yield of Actionable Variants From High-Risk Cancer Gene Panel Testing in Guideline-Eligible and Ineligible Individuals

in Cancer Genetics and Oncogenomics

Sarah S. Lee
Jingwen Zhang
Sara L. Bristow
Susan Rojahn
Mia Mackall
Meenakshi Malhotra
Youbao Sha
Eileen Hoffman
Vivienne Souter
Minetta C Liu

Frontiers in Genetics

Original Research

Accepted on 17 Aug 2026

A methodological framework for developing bioinformatics databases: A case study on the Boesenbergia rotunda genome database

in Computational Genomics

Sarinder Kaur Dhillon
Wai Shi Pang
Chee How Teo
V R Naresh Mutha
Jennifer Ann Harikrishna

Frontiers in Genetics

Original Research

Accepted on 17 Aug 2026

The Expressions and m⁶A Methylation Modification Patterns of mRNAs and lncRNAs in Major Depressive Disorder

in Epigenetics and Genome Architecture

Liang Liu
Zhaonan Yang
Kunru Tan
Shuhao Xu
Jia Xu
Jinbao Niu
Xiuxian Yang

Frontiers in Genetics

Case Report

Accepted on 17 Aug 2026

Adult presentation of SLC29A3-related disorder spectrum with marked hypogammaglobulinemia due to a recurrent homozygous pathogenic variant (G437R): a case report

in Genetics of Common and Rare Diseases

Mohammad Ameen Ishqair
Abbas K. H. Masalma
Mohanad Saleh
Fawaz Awad
ALiaa Khalili
Anas Ameen Ishqair
Somaya Salah
Abed-Rahman N. Saleh

Frontiers in Genetics

Original Research

Accepted on 17 Aug 2026

Missingness-aware machine learning using routine laboratory data for distinguishing hepatitis from cirrhosis

in Computational Genomics

Yang Qin
Xueri Hu
Tinjun Zhang
Qirong Zhu
Chengxing Yin
Zhihui Ren
Jiayi Feng
Cangjie Xue
Juanjuan Kang
Fengjun Liu

Frontiers in Genetics

Original Research

Accepted on 17 Aug 2026

Integrating Single-Cell Multi-Omics for Precision Radiotherapy Stratification in Hypopharyngeal Squamous Cell Carcinoma

in Cancer Genetics and Oncogenomics

Weishi Zhang
Mei Yao

Frontiers in Genetics

Original Research

Accepted on 17 Aug 2026

Genetic diversity, population structure, and linkage disequilibrium among tropical quality protein maize (QPM) lines assessed with high-density SNP markers

in Genomics of Plants and Plant-Associated Organisms

MacDonald Bright Jumbo
SITONIK CHELANG'AT
Dan Makumbi
Manje S Gowda
Boddupalli M Prasanna

Frontiers in Genetics

Editorial

Accepted on 17 Aug 2026

Editorial: Nutrigenetics and Nutrigenomics in Livestock

in Livestock Genomics

Guilherme Henrique Gebim Polizel
Wellison J. S. Diniz
Luiz F. Brito
Miguel HA Santana

Frontiers in Genetics

Original Research

Accepted on 17 Aug 2026

Genomic Analysis Identifies Candidate Supergene Architecture for Host-Feeding Behavior in Wild Aedes aegypti Dengue Vector Mosquitoes

in Applied Genetic Epidemiology

Devojit Kumar Sarma
Sudeesh Warkare
Sweta Mishra
DEEPANKER DAS
Lokendra Rathod
Dr Manoj Kumawat
Siddharth Singh Tomar
Samradhi Singh
MANOJ KUMAR
Rajnarayan R Tiwari

Frontiers in Genetics

Original Research

Accepted on 17 Aug 2026

HSTXGB: a hyperparameter self-tuning XGBoost method integrating pre-and post-processing for gene regulatory network inference

in Computational Genomics

Mingqing Huang
Shun Guo
Fengze Jiang
Yingnan Xiong
Xu Chen

Frontiers in Genetics

Original Research

Published on 17 Aug 2026

Cross-cancer transcriptomic analysis reveals conserved developmental, ferroptosis, and immune remodeling modules in Wilms tumor and oral cancer

in Cancer Genetics and Oncogenomics

Guijun Li
Jinhong Bai
Sai Hu
Xiuli Gao
Fang Wang
Song Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1861806

392 views

Review

Published on 17 Aug 2026

Integrating single-cell transcriptomics with deep learning for glioblastoma treatment

in Computational Genomics

Marybeth G. Yonk
Mainak Mustafi
Megan A. Lim
Kimberly B. Hoang
William H. Delaney
Charee M. Thompson
Thais Federici
Yuhong Du
Nicholas M. Boulis
Antonina Mitrofanova

Frontiers in Genetics

doi 10.3389/fgene.2026.1813369

323 views

Hypothesis and Theory

Accepted on 14 Aug 2026

A Methodological Framework for Real-World Performance Studies of Clinical Variant Classification Platforms at Early Organizational Stages

in Human and Medical Genomics

Vladimir Mitev

Frontiers in Genetics

145 views

Original Research

Accepted on 14 Aug 2026

Development and validation of a machine learning scoring system based on multi-dimensional metabolic signatures for invasive examination triage in intestinal diseases

in Cancer Genetics and Oncogenomics

Jintao He
Jiaorong Chen
Yingbo Rao
Yong Zhang
Mengning He
Mingli Zhu

Frontiers in Genetics

166 views

Review

Accepted on 14 Aug 2026

Plant Stress Memory: Epigenetic Mechanisms for Abiotic Stress Acclimation

in Genomics of Plants and Plant-Associated Organisms

APURBA PAL
AWADHESH KUMAR PAL
Rajendragouda Patil
Sudip Das
Ajay Bhardwaj
Anil Kumar Singh
Duniya Ram Singh

Frontiers in Genetics

160 views

Technology and Code

Published on 14 Aug 2026

FastqCA: an effective FASTQ compressor through 2D spatial redundancy reduction

in Statistical Genetics and Methodology

Shiyang Long
Qingting Wei
Yanni Zou
Yirui Zhou
Jie Lei
Jiaxu Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1827471

405 views

Original Research

Published on 14 Aug 2026

Genetic analysis of Behçet’s disease using whole-exome sequencing and bioinformatics analysis in Korean patients

in Genetics of Common and Rare Diseases

Enkhjargal Bayarsaikhan
Hyunsoo Ahn
Sanguk Kim
Yong-Beom Park
Jae Hoon Lee

Frontiers in Genetics

doi 10.3389/fgene.2026.1787087

502 views

17,056 articles

articles

Comprehensive analysis of SYTL4 differential expression and clinical implications in DLBCL

Repositioning candidate gene approaches in the post-GWAS era: a clinical perspective from psychiatric pharmacogenetics

Diagnostic accuracy of cell-free DNA-based non-invasive prenatal testing for fetal aneuploidies: a systematic review

NLRP3 inflammasome pathway activation is associated with cardiac remodeling, gut microbiota dysbiosis, and dietary protein restriction in a rat heart failure model: an integrative exploratory analysis

Genotype-phenotypic correlation in a Chinese patient with isolated lissencephaly sequence caused by 17p13.3p13.2 chromosomal microdeletion

Presymptomatic Risdiplam in Preterm Monozygotic Twins with Co-occurring Spinal Muscular Atrophy and Tuberous Sclerosis Complex

A Rare De Novo Contiguous 15q11.1-q13.3 Duplication with Tetrasomy (CN=4) and Adjacent Trisomy (CN=3) Associated with Severe Global Developmental Delay, Autism Spectrum Disorder, and Subclinical Epileptiform Discharges: A Case Report and Literature Review

Yield of Actionable Variants From High-Risk Cancer Gene Panel Testing in Guideline-Eligible and Ineligible Individuals

A methodological framework for developing bioinformatics databases: A case study on the Boesenbergia rotunda genome database

The Expressions and m⁶A Methylation Modification Patterns of mRNAs and lncRNAs in Major Depressive Disorder

Adult presentation of SLC29A3-related disorder spectrum with marked hypogammaglobulinemia due to a recurrent homozygous pathogenic variant (G437R): a case report

Missingness-aware machine learning using routine laboratory data for distinguishing hepatitis from cirrhosis

Integrating Single-Cell Multi-Omics for Precision Radiotherapy Stratification in Hypopharyngeal Squamous Cell Carcinoma

Genetic diversity, population structure, and linkage disequilibrium among tropical quality protein maize (QPM) lines assessed with high-density SNP markers

Editorial: Nutrigenetics and Nutrigenomics in Livestock

Genomic Analysis Identifies Candidate Supergene Architecture for Host-Feeding Behavior in Wild Aedes aegypti Dengue Vector Mosquitoes

HSTXGB: a hyperparameter self-tuning XGBoost method integrating pre-and post-processing for gene regulatory network inference

Cross-cancer transcriptomic analysis reveals conserved developmental, ferroptosis, and immune remodeling modules in Wilms tumor and oral cancer

Integrating single-cell transcriptomics with deep learning for glioblastoma treatment

A Methodological Framework for Real-World Performance Studies of Clinical Variant Classification Platforms at Early Organizational Stages

Development and validation of a machine learning scoring system based on multi-dimensional metabolic signatures for invasive examination triage in intestinal diseases

Plant Stress Memory: Epigenetic Mechanisms for Abiotic Stress Acclimation

FastqCA: an effective FASTQ compressor through 2D spatial redundancy reduction

Genetic analysis of Behçet’s disease using whole-exome sequencing and bioinformatics analysis in Korean patients