Frontiers in Genetics

Original Research

Published on 10 Aug 2026

Transcriptomic landscape of human circular RNAs: unveiling molecular mechanisms in high-altitude adaptation

in Human and Medical Genomics

Buhe Bao
Mingxuan Yu
Wei Pang
Ruilin Wang
Wenbin Dong
Ying Bai
Rui Shi
Renjie Wang

Frontiers in Genetics

doi 10.3389/fgene.2026.1823611

215 views

Original Research

Published on 10 Aug 2026

Reduced IQGAP2 promotes esophageal squamous cell carcinoma by regulating MEK/ERK MAPK pathway

in Cancer Genetics and Oncogenomics

Liangcheng Zhao

Frontiers in Genetics

doi 10.3389/fgene.2026.1815586

414 views

Case Report

Published on 10 Aug 2026

A novel TRPC6 variant (c.131C>T, p.(Pro44Leu)) associated with focal segmental glomerulosclerosis: a case report

in Genetics of Common and Rare Diseases

Fan Yang
Xiaoqi Wang
Yan Li
Kaijie Su
Ran Ding
Linlin Wu
Guorong Ma
Jianjie Yang
Zhongxin Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1913168

193 views

Editorial

Published on 10 Aug 2026

Editorial: Cancer cell metabolism and tumor microenvironment remodel

in Cancer Genetics and Oncogenomics

Katsuhiro Yoshimura
Daniela B. Rodriguez-Perera
Rongzhang Dou
Johannes Fahrmann

Frontiers in Genetics

doi 10.3389/fgene.2026.1921001

429 views

Original Research

Published on 10 Aug 2026

Clinical application of long-read sequencing in newborn genetic screening for congenital adrenal hyperplasia

in Genetics of Common and Rare Diseases

Peiran Zhao
Xiaolong Qiu
Qingying Lin
Ting Huang
Yinglin Zeng
Jinfu Zhou
Liangpu Xu

Frontiers in Genetics

doi 10.3389/fgene.2026.1894466

198 views

Original Research

Accepted on 07 Aug 2026

Shared Molecular Mechanisms Between Colorectal Cancer and Cardiovascular Disease Drive Perioperative Neurological Vulnerability

in Human and Medical Genomics

Ling Jiang
Mingqian Yang
Yan Yang
Li Yang
Liyang Xu

Frontiers in Genetics

Original Research

Accepted on 07 Aug 2026

Ultrasound radiomics integrated with an immune-related gene signature for predicting response and resistance to immune checkpoint inhibitors in cutaneous melanoma: a retrospective radiogenomic study with biological validation

in Cancer Genetics and Oncogenomics

Jinyu Peng
Bowen Dai
Kan Ze
Jie Yang

Frontiers in Genetics

393 views

Original Research

Accepted on 07 Aug 2026

Clinical and Genomic Characterization of Corpus Callosum Abnormalities (CCA) in 107 Tunisian Patients Using a Stepwise Diagnostic Approach

in Human and Medical Genomics

Bochra Khadija
Hamza Hadj Abdallah
Wafa slimani
Ayda Bennour
Sarra Dimassi
Najla Soyah
Amira Benzarti
khouloud Rjiba
Wafa Dahleb
Molka Kammoun

Frontiers in Genetics

Original Research

Published on 07 Aug 2026

Confusion, communication, and consent: ELSI barriers to genomics-enhanced remediation in Alberta’s oil sands

in ELSI in Science and Genetics

Michelle Tilford-Shaw
Max Pospisil
Lori Bradford
Graham Strickert
Diane Dupont

Frontiers in Genetics

doi 10.3389/fgene.2026.1889489

482 views

Original Research

Published on 07 Aug 2026

Genetic associations and candidate functional genes linking depression and obesity: a multi-omics integrative study

in Behavioral and Psychiatric Genetics

Xingpei Li
Chunlin Chen
Huibing Li
Yiru He
Kailang Tang
Guanqiao Lai
Ziyang Yang
Wushu Chen
Huihui Yang

Frontiers in Genetics

doi 10.3389/fgene.2026.1855173

476 views

Original Research

Published on 07 Aug 2026

Next‐generation SNPs from lignin biosynthesis gene and transcription factors reveal a hidden teak (Tectona grandis L. f.) lineage: implications for plantation resilience and forest management

in Evolutionary, Population, and Conservation Genetics

Nuzhat Bano
Naseer Mohammad
Shamim Akhtar Ansari

Frontiers in Genetics

doi 10.3389/fgene.2026.1842536

446 views

Review

Published on 07 Aug 2026

Chromatin remodeling and epigenetic regulation of mesenchymal stem/stromal cells in osteoarthritis

in Epigenetics and Genome Architecture

Mo Wu
Cenzhuo Sheng
Hanhao Zhang
Yuxin Chen
Tianyou Ma
Yirui Tong
Pengchao Xu
Peijian Tong
Hanting Xia

Frontiers in Genetics

doi 10.3389/fgene.2026.1877252

440 views

Mini Review

Published on 07 Aug 2026

Human papillomavirus infection and atherosclerotic cardiovascular disease: a comprehensive review of epidemiological evidence, molecular mechanisms, and vaccination-mediated protection

in Human and Medical Genomics

Yiming Meng
Jing Sun
Cuicui Kong
Yushu Ma
Tao Yu

Frontiers in Genetics

doi 10.3389/fgene.2026.1865685

641 views

Original Research

Accepted on 06 Aug 2026

Genome-wide identification of WOX transcription factors and functional characterization of WOX4 and WOX13 involved in cold stress response in Malus baccata

in Genomics of Plants and Plant-Associated Organisms

Tian Yanting
Hao Liu
Fei Wang
Lifang Yang
Xuhong Zhang
Huanyong Li
Xin Qi
Jing Guo

Frontiers in Genetics

Case Report

Accepted on 06 Aug 2026

Glycogen Storage Disease Type VII (Tarui Disease): a case report presenting a PFKM Variant Previously Described Only in Canine Models

in Genetics of Common and Rare Diseases

Mariapia Griffo
Nicola Molitierno
Laura Maria Napoli
Michela Ripolone
Simona Zanotti
Francesco Fortunato
Gabriele Tumminello
Maurizio Moggio
Marco Locatelli
Stefania Corti

Frontiers in Genetics

Editorial

Published on 06 Aug 2026

Editorial: Insights in RNA: 2025

in RNA

Hassan Dastsooz
Naoyuki Kataoka
Nicoletta Potenza

Frontiers in Genetics

doi 10.3389/fgene.2026.1947303

298 views

Case Report

Published on 06 Aug 2026

Case Report: Functional validation of a PKD1 c.7489 + 5G>A variant in an ADPKD family

in Genetics of Common and Rare Diseases

Qiong Pan
Yuefang Liu
Xueping Sun
Shoulian Lu
Lingling Li
Jiandong Shen

Frontiers in Genetics

doi 10.3389/fgene.2026.1850997

390 views

Original Research

Published on 06 Aug 2026

The complete chloroplast genome of Hedera helix (Araliaceae): comparative plastome analyses reveal divergence hotspots, selective constraints, and phylogenetic placement

in Genomics of Plants and Plant-Associated Organisms

Dujuan Zhan
Yaqi Fang
Hao Li
Chencheng Zheng
Jin Jiang
Jie Chen

Frontiers in Genetics

doi 10.3389/fgene.2026.1855347

363 views

Case Report

Accepted on 05 Aug 2026

Differential outcomes associated with the same pathogenic variant: long-term follow-up of a CHARGE syndrome case with a nonsense mutation c.6292C>T in the CHD gene

in Genetics of Common and Rare Diseases

Qiong-yu Wang
Jing-jing Huang
Fu-chun Wang
Jing-wei He

Frontiers in Genetics

Original Research

Published on 05 Aug 2026

Identification and prenatal diagnosis of a novel likely pathogenic ANOS1 variant in a large Chinese Kallmann syndrome family

in Genetics of Common and Rare Diseases

Xiulan Hao
Yanchou Ye
Mancheng Liu
Zhechao Zhang
Haofeng Ning
Xiaonan Wang
Fangchao Tao
Xiujing Huang
Jingran Du
Tian Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1870344

518 views

Original Research

Published on 05 Aug 2026

Risk factors and early warning scoring system for chronic postsurgical pain following video-assisted thoracoscopic surgery in elderly lung cancer patients: a retrospective cohort study

in Cancer Genetics and Oncogenomics

Degui Wang
Weichen Pan
Qinghua Shi
Yuhong Liu

Frontiers in Genetics

doi 10.3389/fgene.2026.1879530

528 views

Review

Published on 05 Aug 2026

From markers to mechanisms: a comprehensive review of major genes and quantitative trait loci shaping the modern sheep (Ovis aries)

in Livestock Genomics

Mostafa Ghaderi-Zefrehei
Effat Nasre Esfahani
Hassan Amini Pozveh
Mohammadreza Hashemi
Parisa Dolati
Sonia Zakizadeh
Maryam Montazeri
Mustafa Muhaghegh Dolatabady
Ikhide Godwin Imumorin
Mohammad Hossein Banabazi

Frontiers in Genetics

doi 10.3389/fgene.2026.1865980

603 views

Hypothesis and Theory

Accepted on 04 Aug 2026

Economic impact of biomarker-based aging interventions on healthcare costs and individual value

in Epigenetics and Genome Architecture

Federico Felizzi

Frontiers in Genetics

Original Research

Published on 04 Aug 2026

Preimplantation genetic testing and prenatal diagnosis of TANGO2 deficiency disorder with biallelic pathogenic variants using single-nucleotide polymorphism-based haplotyping and gap-polymerase chain reaction

in Genetics of Common and Rare Diseases

Wanna Ke
Xiaojun Wen
Zhanhui Ou
Xiaowu Fang
Junye Huo
Xiufeng Lin
Xubin Zhang
Zhiming Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1832329

414 views

17,034 articles

articles

Transcriptomic landscape of human circular RNAs: unveiling molecular mechanisms in high-altitude adaptation

Reduced IQGAP2 promotes esophageal squamous cell carcinoma by regulating MEK/ERK MAPK pathway

A novel TRPC6 variant (c.131C>T, p.(Pro44Leu)) associated with focal segmental glomerulosclerosis: a case report

Editorial: Cancer cell metabolism and tumor microenvironment remodel

Clinical application of long-read sequencing in newborn genetic screening for congenital adrenal hyperplasia

Shared Molecular Mechanisms Between Colorectal Cancer and Cardiovascular Disease Drive Perioperative Neurological Vulnerability

Ultrasound radiomics integrated with an immune-related gene signature for predicting response and resistance to immune checkpoint inhibitors in cutaneous melanoma: a retrospective radiogenomic study with biological validation

Clinical and Genomic Characterization of Corpus Callosum Abnormalities (CCA) in 107 Tunisian Patients Using a Stepwise Diagnostic Approach

Confusion, communication, and consent: ELSI barriers to genomics-enhanced remediation in Alberta’s oil sands

Genetic associations and candidate functional genes linking depression and obesity: a multi-omics integrative study

Next‐generation SNPs from lignin biosynthesis gene and transcription factors reveal a hidden teak (Tectona grandis L. f.) lineage: implications for plantation resilience and forest management

Chromatin remodeling and epigenetic regulation of mesenchymal stem/stromal cells in osteoarthritis

Human papillomavirus infection and atherosclerotic cardiovascular disease: a comprehensive review of epidemiological evidence, molecular mechanisms, and vaccination-mediated protection

Genome-wide identification of WOX transcription factors and functional characterization of WOX4 and WOX13 involved in cold stress response in Malus baccata

Glycogen Storage Disease Type VII (Tarui Disease): a case report presenting a PFKM Variant Previously Described Only in Canine Models

Editorial: Insights in RNA: 2025

Case Report: Functional validation of a PKD1 c.7489 + 5G>A variant in an ADPKD family

The complete chloroplast genome of Hedera helix (Araliaceae): comparative plastome analyses reveal divergence hotspots, selective constraints, and phylogenetic placement

Differential outcomes associated with the same pathogenic variant: long-term follow-up of a CHARGE syndrome case with a nonsense mutation c.6292C>T in the CHD gene

Identification and prenatal diagnosis of a novel likely pathogenic ANOS1 variant in a large Chinese Kallmann syndrome family

Risk factors and early warning scoring system for chronic postsurgical pain following video-assisted thoracoscopic surgery in elderly lung cancer patients: a retrospective cohort study

From markers to mechanisms: a comprehensive review of major genes and quantitative trait loci shaping the modern sheep (Ovis aries)

Economic impact of biomarker-based aging interventions on healthcare costs and individual value

Preimplantation genetic testing and prenatal diagnosis of TANGO2 deficiency disorder with biallelic pathogenic variants using single-nucleotide polymorphism-based haplotyping and gap-polymerase chain reaction