Frontiers in Genetics

Mini Review

Published on 01 Apr 2026

Federated, governed, and interoperable? The emerging architecture of public human genomic data infrastructures: a European perspective

in Computational Genomics

Marco Antonio Tangaro
Matteo Chiara
Graziano Pesole
Federico Zambelli

Frontiers in Genetics

doi 10.3389/fgene.2026.1819270

Original Research

Published on 01 Apr 2026

Serum tumor markers combined with HRCT for malignancy risk assessment of solitary pulmonary nodules: a retrospective study

in Cancer Genetics and Oncogenomics

Yong Zhou
Shuitang Wang
Yongqiu Zhang

Frontiers in Genetics

doi 10.3389/fgene.2026.1731395

Original Research

Published on 01 Apr 2026

Genetic association of LOC100130476 rs80213143 with susceptibility and renal involvement in systemic lupus erythematosus

in Genetics of Common and Rare Diseases

Xiao-Xue Zhang
Jun-Peng You
Yong-Chun Li
Hong-De Xu
Xin-Yi Chen
Kai-Le Feng
Zhi-Qiu He
Zhan-Zheng Zhao
Yuan-Yuan Qi

Frontiers in Genetics

doi 10.3389/fgene.2026.1609849

Original Research

Published on 01 Apr 2026

TTN variants in pediatric cardiomyopathy: a retrospective cohort study

in Genetics of Common and Rare Diseases

Yu Qiu
Lei Liu
Kaiyu Zhou
Yifei Li
Yimin Hua

Frontiers in Genetics

doi 10.3389/fgene.2026.1758524

Editorial

Accepted on 31 Mar 2026

Editorial: Chromatin Modifications and Gene Expression: From Mechanisms to Therapeutic Implications in Disease

in Epigenomics and Epigenetics

Liliana Burlibasa
Giovanni Nassa
Anca Botezatu
Annamaria Salvati

Frontiers in Genetics

Case Report

Accepted on 31 Mar 2026

X-linked Recessive Ichthyosis with X-linked Retinoschisis in Two Brothers: A Case Report

in Genetics of Common and Rare Diseases

Kou Liu
Xiaojun Du
Xiaohan Yang
Chunli Chen

Frontiers in Genetics

Original Research

Accepted on 31 Mar 2026

Clinical outcomes of preimplantation genetic testing for structural rearrangements in couples with chromosomal inversions: a retrospective analysis

in Genetics of Common and Rare Diseases

Yutong Li
Yuezhi Keqie
Cui-Ting Peng
Han Chen
Jun Ren
Hong Yang
Zhushu Liu
Wei Fan
Shan Luo
XUEMEI ZHANG

Frontiers in Genetics

Original Research

Accepted on 31 Mar 2026

Lipid metabolism-driven gene expression predicts prognostic outcomes in lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Xianyong Li
Qianqian Tang
Xuankai Wang
Na Liu
Jianjun Xu

Frontiers in Genetics

Case Report

Accepted on 31 Mar 2026

Case Report:Co-inheritance of Familial Lecithin-Cholesterol Acyltransferase Deficiency and α0-Thalassemia

in Genetics of Common and Rare Diseases

Yinbing Zhu
Chunya Liu
Wenxun Tang
Yi Jiang
Lingling Mao
Min Huang

Frontiers in Genetics

Review

Accepted on 31 Mar 2026

Long noncoding RNAs, microRNAs, and circular RNAs landscape in hypertensive disorders of pregnancy: Progress, challenges, and perspectives

in Epigenomics and Epigenetics

Ting Xu
Xi Yu
Bingyu Ji
Yueming Zhang
Ruiqing Tong
Qinqin Gao

Frontiers in Genetics

Brief Research Report

Accepted on 31 Mar 2026

Application of Integrated Nested Laplace Approximation to identify hotspots of methylation heterogeneity in healthy individuals from the MAMELI cohort

in Computational Genomics

Tiago Nardi
Eva Dariol
Rachele Matsagani
Donya Zojaji
Stefano Gustincich
Luca Pandolfini
Elia Mario Biganzoli
Valentina Bollati

Frontiers in Genetics

Original Research

Accepted on 31 Mar 2026

Evaluation of the contribution of trio-exome sequencing in selected prenatal indications

in Genetics of Common and Rare Diseases

Manon CHRETIEN
Julien OSOUF
Carine ABEL
Alexandra AFENJAR
Tania ATTIE-BITACH
Elise BRISCHOUX-BOUCHER
Lydie BURGLEN
Nadege Calmels
Nicolas CHASSAING
Thomas Courtin

Frontiers in Genetics

Data Report

Published on 31 Mar 2026

A single-cell multi-omics atlas of human eyelid skin

in Computational Genomics

Weiguang Ma
Yanwen Xu
Junjie Chen
Yue Yuan
Xiaoyu Wei
Qiuting Deng
Ruikang Li
Jiaxin Du
Zhongjin Zhang
Zhentao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2026.1780660

160 views

Original Research

Published on 31 Mar 2026

Genomic and transcriptomic insights into aflatoxin-induced intrahepatic cholangiocarcinoma: an integrated pathway and meta-analysis study

in Computational Genomics

Fengping Li
Yuanyang Ma
Yan Cheng
Shanshan Zou

Frontiers in Genetics

doi 10.3389/fgene.2026.1785259

Original Research

Accepted on 30 Mar 2026

Clinical variant interpretation comparing two saturation genome editing-based functional studies for BRCA2

in Cancer Genetics and Oncogenomics

Ju Hyeon Shin
KYUNG SUN PARK
Young-gon Kim
Mi-Ae Jang
Ja-Hyun Jang
Jong-Won Kim

Frontiers in Genetics

Original Research

Accepted on 30 Mar 2026

Identification and molecular functional analysis of genes associated with addiction using integrated genetic web-based programs and databases

in Behavioral and Psychiatric Genetics

Waheeda A Hossain
Merlin G. Butler

Frontiers in Genetics

Original Research

Accepted on 30 Mar 2026

Sez6l promotes neuropathic pain via Wnt5a/Ca²⁺ pathways in dorsal root ganglion

in Neurogenomics

junjie chen
limin hu

Frontiers in Genetics

Original Research

Accepted on 30 Mar 2026

Prevalence of GSTM1 and GSTT1 Null Polymorphisms in an Admixed Healthy Venezuelan Population: Implications for Pharmacogenetic Baselines

in Cancer Genetics and Oncogenomics

Mercedes Teresita Fernandez Mestre
Eva Salazar-Alcalá
Juan Bautista De Sanctis
Dolores Moreno
Jenny Garmendia
Oriana Regalado-Gutiérrez
María Johanna Peña

Frontiers in Genetics

Systematic Review

Accepted on 30 Mar 2026

Development and research trends of stay-green biology in legumes: A bibliometric and visual analysis over three decades

in Genomics of Plants and Plant-Associated Organisms

Shubh Pravat Singh Yadav
Upama Adhikari
James Myers
Lyle Wallace

Frontiers in Genetics

Original Research

Published on 30 Mar 2026

Expanding the clinical and mutational spectrum of hereditary spastic paraplegia type 4 in a cohort of patients from central China

in Genetics of Common and Rare Diseases

Jun Fu
Jia Song
Gang Li
Mi Pang
Jiewen Zhang
Mingming Ma

Frontiers in Genetics

doi 10.3389/fgene.2026.1800987

Original Research

Published on 30 Mar 2026

Raloxifene ameliorates cartilage and subchondral bone microstructural degeneration in the ovariectomy-induced spontaneous postmenopausal osteoarthritis

in Evolutionary, Population, and Conservation Genetics

Ya-Ping Xiao
Mu-Wei Dai
Fa-Ming Tian
Li-Tao Shao
Ming-Jian Bei
Liu Zhang
Zhang-Hua Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1795443

Brief Research Report

Published on 30 Mar 2026

Pharmacist workforce training in pharmacogenomics with a focus on rural and underserved areas

in Pharmacogenetics and Pharmacogenomics

Moataz Mohamed
Pamala A. Jacobson
Alyssa Johnson
Jacob Tyler Brown

Frontiers in Genetics

doi 10.3389/fgene.2026.1794122

189 views

Case Report

Published on 30 Mar 2026

Case Report: Prenatal genetic analysis of a rare fetus with 45, X/46, X, dic r (Y; Y)/46, X, r(Y) karyotype

in Genetics of Common and Rare Diseases

Guosheng Deng
Xiafei Liang
Yuqing Lai
Jujie Song
Jinjie Pan
Yinghong Lu
Lili Li
Yunning Liang

Frontiers in Genetics

doi 10.3389/fgene.2026.1758508

Brief Research Report

Published on 30 Mar 2026

Renpenning syndrome caused by the c.459_462delAGAG mutation in PQBP1: a case report and literature review

in Human and Medical Genomics

Mengting Zhang
Mengli Liu
Rongrong Wang
Fuxiang Ma
Guoshun Mao

Frontiers in Genetics

doi 10.3389/fgene.2026.1642438

351 views

16,688 articles

articles

Federated, governed, and interoperable? The emerging architecture of public human genomic data infrastructures: a European perspective

Serum tumor markers combined with HRCT for malignancy risk assessment of solitary pulmonary nodules: a retrospective study

Genetic association of LOC100130476 rs80213143 with susceptibility and renal involvement in systemic lupus erythematosus

TTN variants in pediatric cardiomyopathy: a retrospective cohort study

Editorial: Chromatin Modifications and Gene Expression: From Mechanisms to Therapeutic Implications in Disease

X-linked Recessive Ichthyosis with X-linked Retinoschisis in Two Brothers: A Case Report

Clinical outcomes of preimplantation genetic testing for structural rearrangements in couples with chromosomal inversions: a retrospective analysis

Lipid metabolism-driven gene expression predicts prognostic outcomes in lung adenocarcinoma

Case Report:Co-inheritance of Familial Lecithin-Cholesterol Acyltransferase Deficiency and α0-Thalassemia

Long noncoding RNAs, microRNAs, and circular RNAs landscape in hypertensive disorders of pregnancy: Progress, challenges, and perspectives

Application of Integrated Nested Laplace Approximation to identify hotspots of methylation heterogeneity in healthy individuals from the MAMELI cohort

Evaluation of the contribution of trio-exome sequencing in selected prenatal indications

A single-cell multi-omics atlas of human eyelid skin

Genomic and transcriptomic insights into aflatoxin-induced intrahepatic cholangiocarcinoma: an integrated pathway and meta-analysis study

Clinical variant interpretation comparing two saturation genome editing-based functional studies for BRCA2

Identification and molecular functional analysis of genes associated with addiction using integrated genetic web-based programs and databases

Sez6l promotes neuropathic pain via Wnt5a/Ca²⁺ pathways in dorsal root ganglion

Prevalence of GSTM1 and GSTT1 Null Polymorphisms in an Admixed Healthy Venezuelan Population: Implications for Pharmacogenetic Baselines

Development and research trends of stay-green biology in legumes: A bibliometric and visual analysis over three decades

Expanding the clinical and mutational spectrum of hereditary spastic paraplegia type 4 in a cohort of patients from central China

Raloxifene ameliorates cartilage and subchondral bone microstructural degeneration in the ovariectomy-induced spontaneous postmenopausal osteoarthritis

Pharmacist workforce training in pharmacogenomics with a focus on rural and underserved areas

Case Report: Prenatal genetic analysis of a rare fetus with 45, X/46, X, dic r (Y; Y)/46, X, r(Y) karyotype

Renpenning syndrome caused by the c.459_462delAGAG mutation in PQBP1: a case report and literature review