ORIGINAL RESEARCH article
Front. Genet.
Sec. Livestock Genomics
Volume 16 - 2025 | doi: 10.3389/fgene.2025.1576125
This article is part of the Research TopicAdvances in Livestock Genetics: Enhancing Breeding Practices and Improving Animal HealthView all 12 articles
Inbreeding Patterns and Genetic Diversity Under Selection in Teha Sheep
Provisionally accepted
- 1Xinjiang Academy of Animal Science, Ürümqi, China
- 2Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, China
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Background Inbreeding and genetic diversity are critical factors influencing the adaptability, productivity, and sustainability of livestock populations. Teha sheep, a crossbred line between Texel and Kazakh sheep, are an important meat-producing breed in China, yet their genetic structure and inbreeding status remain underexplored.This study aims to evaluate inbreeding coefficients, genetic diversity, and selection signatures in Teha sheep by integrating pedigree and genomic data.Analysis of pedigree data from 2,652 individuals revealed a low inbreeding coefficient (FPED = 0.001), while genomic data from 1,271 individuals indicated slightly higher inbreeding coefficients, with the FROH averaging 0.044. Genetic diversity metrics, including Ho = 0.347 and PIC = 0.345, confirmed moderate variability within the population. A significant region of ROH hotspot was identified on chromosome 2 (112.01-119.89 Mb), encompassing genes such as MSTN, TUBGCP5, and NIPA2, which are associated with muscle growth, fat metabolism,
Keywords: ARHGEF4, ASNSD1, BIN1, C2H2, C CDC115, COL3A1, Col5a2, CYFIP1
Received: 13 Feb 2025; Accepted: 28 May 2025.
Copyright: © 2025 Wang, Liang, Ziyayiding, Jiao, Kasimu, He and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Sangang He, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310000, Zhejiang, China
Mingjun Liu, Xinjiang Academy of Animal Science, Ürümqi, China
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