Frontiers in Genetics | Statistical Genetics and Methodology

Original Research

Published on 21 Jun 2019

Identification via Numerical Computation of Transcriptional Determinants of a Cell Phenotype Decision Making

in Statistical Genetics and Methodology

Marilisa Cortesi
Alice Pasini
Simone Furini
Emanuele Giordano

Frontiers in Genetics

doi 10.3389/fgene.2019.00575

2,384 views
11 citations

Original Research

Published on 19 Jun 2019

metaFARVAT: An Efficient Tool for Meta-Analysis of Family-Based, Case-Control, and Population-Based Rare Variant Association Studies

in Statistical Genetics and Methodology

Longfei Wang
Sungyoung Lee
Dandi Qiao
Michael H. Cho
Edwin K. Silverman
Christoph Lange
Sungho Won

Frontiers in Genetics

doi 10.3389/fgene.2019.00572

3,255 views
3 citations

Original Research

Published on 06 Jun 2019

Microbial Networks in SPRING - Semi-parametric Rank-Based Correlation and Partial Correlation Estimation for Quantitative Microbiome Data

in Statistical Genetics and Methodology

Grace Yoon
Irina Gaynanova
Christian L. Müller

Frontiers in Genetics

doi 10.3389/fgene.2019.00516

12,478 views
93 citations

Review

Published on 04 Jun 2019

Review of Causal Discovery Methods Based on Graphical Models

in Statistical Genetics and Methodology

Clark Glymour
Kun Zhang
Peter Spirtes

Frontiers in Genetics

doi 10.3389/fgene.2019.00524

169,695 views
613 citations

Original Research

Published on 29 May 2019

Systems Chemical Genetics-Based Drug Discovery: Prioritizing Agents Targeting Multiple/Reliable Disease-Associated Genes as Drug Candidates

in Statistical Genetics and Methodology

Yuan Quan
Zhi-Hui Luo
Qing-Yong Yang
Jiang Li
Qiang Zhu
Ye-Mao Liu
Bo-Min Lv
Ze-Jia Cui
Xuan Qin
Yan-Hua Xu

Frontiers in Genetics

doi 10.3389/fgene.2019.00474

6,521 views
14 citations

Original Research

Published on 22 May 2019

Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells

in Statistical Genetics and Methodology

Emma Jonasson
Salim Ghannoum
Emma Persson
Joakim Karlsson
Thomas Kroneis
Erik Larsson
Göran Landberg
Anders Ståhlberg

Frontiers in Genetics

doi 10.3389/fgene.2019.00500

13,242 views
28 citations

Methods

Published on 21 May 2019

Learning Causal Biological Networks With the Principle of Mendelian Randomization

in Statistical Genetics and Methodology

Md. Bahadur Badsha
Audrey Qiuyan Fu

Frontiers in Genetics

doi 10.3389/fgene.2019.00460

11,632 views
49 citations

Original Research

Published on 17 May 2019

Considering Genetic Heterogeneity in the Association Analysis Finds Genes Associated With Nicotine Dependence

in Statistical Genetics and Methodology

Xuefen Zhang
Tongtong Lan
Tong Wang
Wei Xue
Xiaoran Tong
Tengfei Ma
Guifen Liu
Qing Lu

Frontiers in Genetics

doi 10.3389/fgene.2019.00448

3,056 views
5 citations

Original Research

Published on 17 May 2019

Multi-Omic Analysis of the Microbiome and Metabolome in Healthy Subjects Reveals Microbiome-Dependent Relationships Between Diet and Metabolites

in Statistical Genetics and Methodology

Zheng-Zheng Tang
Guanhua Chen
Qilin Hong
Shi Huang
Holly M. Smith
Rachana D. Shah
Matthew Scholz
Jane F. Ferguson

Frontiers in Genetics

doi 10.3389/fgene.2019.00454

41,432 views
122 citations

Methods

Published on 16 May 2019

A Distance-Based Kernel Association Test Based on the Generalized Linear Mixed Model for Correlated Microbiome Studies

in Statistical Genetics and Methodology

Hyunwook Koh
Yutong Li
Xiang Zhan
Jun Chen
Ni Zhao

Frontiers in Genetics

doi 10.3389/fgene.2019.00458

7,493 views
45 citations

Original Research

Published on 24 Apr 2019

An Adaptive Multivariate Two-Sample Test With Application to Microbiome Differential Abundance Analysis

in Statistical Genetics and Methodology

Kalins Banerjee
Ni Zhao
Arun Srinivasan
Lingzhou Xue
Steven D. Hicks
Frank A. Middleton
Rongling Wu
Xiang Zhan

Frontiers in Genetics

doi 10.3389/fgene.2019.00350

10,258 views
13 citations

Original Research

Published on 24 Apr 2019

A Log-Ratio Biplot Approach for Exploring Genetic Relatedness Based on Identity by State

in Statistical Genetics and Methodology

Jan Graffelman
Iván Galván Femenía
Rafael de Cid
Carles Barceló Vidal

Frontiers in Genetics

doi 10.3389/fgene.2019.00341

4,669 views
3 citations

Methods

Published on 16 Apr 2019

Family-Based Haplotype Estimation and Allele Dosage Correction for Polyploids Using Short Sequence Reads

in Statistical Genetics and Methodology

Ehsan Motazedi
Chris Maliepaard
Richard Finkers
Richard Visser
Dick de Ridder

Frontiers in Genetics

doi 10.3389/fgene.2019.00335

6,623 views
12 citations

Review

Published on 22 Mar 2019

Bayesian Inference for Mixed Model-Based Genome-Wide Analysis of Expression Quantitative Trait Loci by Gibbs Sampling

in Statistical Genetics and Methodology

Chaeyoung Lee

Frontiers in Genetics

doi 10.3389/fgene.2019.00199

7,047 views
5 citations

Original Research

Published on 14 Mar 2019

Factors Affecting the Accuracy of Genomic Selection for Agricultural Economic Traits in Maize, Cattle, and Pig Populations

in Statistical Genetics and Methodology

Haohao Zhang
Lilin Yin
Meiyue Wang
Xiaohui Yuan
Xiaolei Liu

Frontiers in Genetics

doi 10.3389/fgene.2019.00189

20,282 views
141 citations

Hypothesis and Theory

Published on 05 Mar 2019

Orthogonal Decomposition of the Genetic Variance for Epistatic Traits Under Linkage Disequilibrium—Applications to the Analysis of Bateson-Dobzhansky-Müller Incompatibilities and Sign Epistasis

in Statistical Genetics and Methodology

José M. Álvarez-Castro
Rosa M. Crujeiras

Frontiers in Genetics

doi 10.3389/fgene.2019.00054

3,565 views
7 citations