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CASE REPORT article

Front. Glob. Women’s Health

Sec. Quality of Life

Avoiding Soy Foods and Certain Nuts and Seed Foods in the Management of Severe Cyclical Mastalgia: A Case Report

Provisionally accepted
Kaifeng  DengKaifeng Deng*Qiaoyun  ZHangQiaoyun ZHangRuzhen  WeiRuzhen Wei
  • The Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, 545005, China, Liuzhou, China

The final, formatted version of the article will be published soon.

Severe cyclical mastalgia is a common condition that can substantially impair women's daily activities and quality of life. Pharmacological treatments are often used, but non-pharmacological strategies remain underexplored. We report a case of a 28-year-old woman with long-standing severe cyclical mastalgia and hyperprolactinemia, who achieved symptom resolution through strict avoidance of soy foods and certain nuts, while maintaining her usual lifestyle and diet otherwise. Hormonal measurements indicated decreases in premenstrual prolactin, progesterone and estradiol levels, and even minimal intake of these foods provoked mild breast discomfort. This case suggests a potential link between soy consumption and cyclical mastalgia in susceptible individuals and highlights the possibility of non-pharmacological dietary management. Further research is needed to assess the efficacy, safety, and broader applicability of this approach.

Keywords: soy, Nut, seed, Cyclical mastalgia, case report, hormone analogs

Received: 01 Jul 2025; Accepted: 08 Dec 2025.

Copyright: © 2025 Deng, ZHang and Wei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Kaifeng Deng

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