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BRIEF RESEARCH REPORT article

Front. Hum. Neurosci.

Sec. Brain Imaging and Stimulation

Lumbar Enlargement Spinal Cord Stimulation for Severe Spasticity and Motor Function Improvement After Traumatic Brain Injury: A Case Report

Provisionally accepted
Di  WuDi Wu1Yaping  WangYaping Wang1Bo  HongBo Hong2*
  • 1Department of Pain Management, Second Xiangya Hospital, Central South University, Changsha, China
  • 2Yueyang Traditional Chinese Medicine Hospital, Yue yang, China

The final, formatted version of the article will be published soon.

This case report describes the successful use of epidural spinal cord stimulation (SCS) in managing severe, refractory spasticity in a 58-year-old male following traumatic brain injury. Despite nearly eight months of conventional pharmacotherapy and rehabilitation for his tetraplegia, his lower-limb spasticity persisted at Modified Ashworth Scale (MAS) grade 3, severely impeding functional recovery. After implantation of a trial and subsequently permanent SCS system at the lumbar enlargement, muscle tone decreased to MAS grade 2 within 48 hours, alongside improvements in muscle strength. Over six months, stimulation led to a marked reduction in the frequency and severity of spastic episodes. This spasticity relief fundamentally improved the patient's sleep quality and enabled significant functional gains, including assisted standing and pedal stepping. This case demonstrates the positive effect of SCS for a condition often resistant to standard treatments. The results support re-evaluating SCS's therapeutic potential for refractory spasticity caused by TBI and other central nervous system disorders, potentially through mechanisms involving the modulation of spinal cord excitability.

Keywords: case report, Refractory, Spasticity, Spinal Cord Stimulation, Traumatic Brain Injury

Received: 04 Dec 2025; Accepted: 16 Feb 2026.

Copyright: © 2026 Wu, Wang and Hong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Bo Hong

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