Frontiers in Medical Technology | Pharmaceutical Innovation

Mini Review

Published on 11 Dec 2020

Mode-of-Action of Antimicrobial Peptides: Membrane Disruption vs. Intracellular Mechanisms

in Pharmaceutical Innovation

Aurélie H. Benfield
Sónia Troeira Henriques

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.610997

50,925 views
315 citations

Original Research

Published on 03 Dec 2020

Enhanced Immune Responses and Protective Immunity to Zika Virus Induced by a DNA Vaccine Encoding a Chimeric NS1 Fused With Type 1 Herpes Virus gD Protein

in Pharmaceutical Innovation

Lennon Ramos Pereira
Rúbens Prince dos Santos Alves
Natiely Silva Sales
Robert Andreata-Santos
Aléxia Adrianne Venceslau-Carvalho
Samuel Santos Pereira
Maria Fernanda Castro-Amarante
Mônica Josiane Rodrigues-Jesus
Marianna Teixeira de Pinho Favaro
Rosa Maria Chura-Chambi

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.604160

4,888 views
5 citations

Review

Published on 30 Nov 2020

Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury

in Pharmaceutical Innovation

Christopher R. Cox
Stephen Lynch
Christopher Goldring
Parveen Sharma

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.611913

15,333 views
46 citations

Correction

Published on 27 Nov 2020

Corrigendum: Protective Immunity to Dengue Virus Induced by DNA Vaccines Encoding Nonstructural Proteins in a Lethal Challenge Immunocompetent Mouse Model

in Pharmaceutical Innovation

Rúbens Prince dos Santos Alves
Robert Andreata-Santos
Carla Longo de Freitas
Lennon Ramos Pereira
Denicar Lina Nascimento Fabris-Maeda
Mônica Josiane Rodrigues-Jesus
Samuel Santos Pereira
Alexia Adrianne Venceslau Brito Carvalho
Natiely Silva Sales
Jean Pierre Schatzmann Peron

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.626114

1,747 views
4 citations

Original Research

Published on 17 Nov 2020

Design of a Multi-Control Objective Rescue Mechanical Ventilation System (Linshomator)

in Pharmaceutical Innovation

Aritra Roy
Pushpak Singh
Simran Saha
Arvil Sen
Mayukh Ray
Samarpan Deb Majumder
Sagnik Dutta
Shubho Chowdhuri
Raghav Mundhra

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.575964

4,768 views

Brief Research Report

Published on 17 Nov 2020

Structure-Based Modeling of SARS-CoV-2 Peptide/HLA-A02 Antigens

in Pharmaceutical Innovation

Santrupti Nerli
Nikolaos G. Sgourakis

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.553478

7,336 views
21 citations

Review

Published on 16 Nov 2020

In vitro Studies of Transendothelial Migration for Biological and Drug Discovery

in Pharmaceutical Innovation

Alec T. Salminen
Zahra Allahyari
Shayan Gholizadeh
Molly C. McCloskey
Raquel Ajalik
Renee N. Cottle
Thomas R. Gaborski
James L. McGrath

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.600616

17,322 views
36 citations

Original Research

Published on 30 Oct 2020

Protective Immunity to Dengue Virus Induced by DNA Vaccines Encoding Nonstructural Proteins in a Lethal Challenge Immunocompetent Mouse Model

in Pharmaceutical Innovation

Rúbens Prince dos Santos Alves
Robert Andreata-Santos
Carla Longo de Freitas
Lennon Ramos Pereira
Denicar Lina Nascimento Fabris-Maeda
Mônica Josiane Rodrigues-Jesus
Samuel Santos Pereira
Alexia Adrianne Venceslau Brito Carvalho
Natiely Silva Sales
Jean Pierre Schatzmann Peron

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.558984

4,053 views
5 citations

Mini Review

Published on 21 Oct 2020

Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases

in Pharmaceutical Innovation

Ziyang Xu
Ami Patel
Nicholas J. Tursi
Xizhou Zhu
Kar Muthumani
Daniel W. Kulp
David B. Weiner

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.571030

30,897 views
40 citations

Original Research

Published on 22 Sep 2020

The 100 Most Influential Studies in Chimeric Antigen Receptor T-Cell: A Bibliometric Analysis

in Pharmaceutical Innovation

Beomjun Seo
Seungwook Kim
Jeeyoon Kim

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.00003

6,298 views
4 citations

Methods

Published on 07 Aug 2020

Robust Formation of an Epithelial Layer of Human Intestinal Organoids in a Polydimethylsiloxane-Based Gut-on-a-Chip Microdevice

in Pharmaceutical Innovation

Woojung Shin
Yoko M. Ambrosini
Yong Cheol Shin
Alexander Wu
Soyoun Min
Domin Koh
Sowon Park
Seung Kim
Hong Koh
Hyun Jung Kim

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.00002

12,193 views
27 citations

Specialty Grand Challenge

Published on 09 Jan 2020

Pharmaceutical Innovations: The Grand Challenges Ahead

in Pharmaceutical Innovation

Rita I. Aroeira
Miguel A. R. B. Castanho

Frontiers in Medical Technology

doi 10.3389/fmedt.2019.00003

9,805 views
1 citation

60 articles

articles

Mode-of-Action of Antimicrobial Peptides: Membrane Disruption vs. Intracellular Mechanisms

Enhanced Immune Responses and Protective Immunity to Zika Virus Induced by a DNA Vaccine Encoding a Chimeric NS1 Fused With Type 1 Herpes Virus gD Protein

Current Perspective: 3D Spheroid Models Utilizing Human-Based Cells for Investigating Metabolism-Dependent Drug-Induced Liver Injury

Corrigendum: Protective Immunity to Dengue Virus Induced by DNA Vaccines Encoding Nonstructural Proteins in a Lethal Challenge Immunocompetent Mouse Model

Design of a Multi-Control Objective Rescue Mechanical Ventilation System (Linshomator)

Structure-Based Modeling of SARS-CoV-2 Peptide/HLA-A02 Antigens

In vitro Studies of Transendothelial Migration for Biological and Drug Discovery

Protective Immunity to Dengue Virus Induced by DNA Vaccines Encoding Nonstructural Proteins in a Lethal Challenge Immunocompetent Mouse Model

Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases

The 100 Most Influential Studies in Chimeric Antigen Receptor T-Cell: A Bibliometric Analysis

Robust Formation of an Epithelial Layer of Human Intestinal Organoids in a Polydimethylsiloxane-Based Gut-on-a-Chip Microdevice

Pharmaceutical Innovations: The Grand Challenges Ahead